Role of DNA methylation in the regulation of the RANKL-OPG system in human bone

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Denosumab improves density and strength parameters as measured by QCT of the radius in postmenopausal women with low bone mineral density

(2010) H.K. Genant et al.   BONE

Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry

(2010) María Berdasco et al.   DEVELOPMENTAL CELL

Function of OPG as a traffic regulator for RANKL is crucial for controlled osteoclastogenesis

(2010) Shigeki Aoki et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone and bone marrow pro-osteoclastogenic cytokines are up-regulated in osteoporosis fragility fractures

(2010) P. D’Amelio et al.   OSTEOPOROSIS INTERNATIONAL

Genetic and epigenetic regulation of aging

(2009) Mario F Fraga   CURRENT OPINION IN IMMUNOLOGY

DNA methylation and histone modification regulate silencing of OPG during tumor progression

(2009) Tung-Ying Lu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Functions of RANKL/RANK/OPG in bone modeling and remodeling

(2008) Brendan F. Boyce et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development

(2008) Samir Kumar Patra et al.   CANCER AND METASTASIS REVIEWS

Effects of Denosumab on Bone Mineral Density and Bone Turnover in Postmenopausal Women

(2008) Henry G. Bone et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE