SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart

Transcriptional and Cellular Diversity of the Human Heart

(2020) Nathan R. Tucker et al.   CIRCULATION

Neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo

(2020) Ivan-Maximiliano Kur et al.   PLOS BIOLOGY

ARHGAP24 inhibits cell proliferation and cell cycle progression and induces apoptosis of lung cancer via a STAT6-WWP2-p27 axis

(2019) Lei Wang et al.   CARCINOGENESIS

RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling

(2018) Maarten M. G. van den Hoogenhof et al.   CIRCULATION

Plasma Circulating Extracellular RNAs in Left Ventricular Remodeling Post-Myocardial Infarction

(2018) Kirsty M. Danielson et al.   EBioMedicine

Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts

(2018) Peng Hu et al.   GENES & DEVELOPMENT

Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

(2018) Mary E. Sweet et al.   BMC GENOMICS

Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease

(2018) Matthew Ackers-Johnson et al.   Nature Communications

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Extracellular Vesicles: Unique Intercellular Delivery Vehicles

(2017) Sybren L.N. Maas et al.   TRENDS IN CELL BIOLOGY

Current Perspectives on In Vivo Noninvasive Tracking of Extracellular Vesicles with Molecular Imaging

(2017) Prakash Gangadaran et al.   Biomed Research International

From Erythroblasts to Mature Red Blood Cells: Organelle Clearance in Mammals

(2017) Martina Moras et al.   Frontiers in Physiology

Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson’s disease?

(2017) Junichi Matsumoto et al.   Acta Neuropathologica Communications

A comparative strategy for single-nucleus and single-cell transcriptomes confirms accuracy in predicted cell-type expression from nuclear RNA

(2017) Blue B. Lake et al.   Scientific Reports

Cardiac Remodeling: Concepts, Clinical Impact, Pathophysiological Mechanisms and Pharmacologic Treatment

(2016) Paula S. Azevedo et al.   Arquivos Brasileiros de Cardiologia

A Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse HeartNovelty and Significance

(2016) Matthew Ackers-Johnson et al.   CIRCULATION RESEARCH

Plasma-derived Extracellular Vesicles Contain Predictive Biomarkers and Potential Therapeutic Targets for Myocardial Ischemic (MI) Injury

(2016) Esther Sok Hwee Cheow et al.   MOLECULAR & CELLULAR PROTEOMICS

Monocyte-mediated activation of endothelial cells occurs only after binding to extracellular vesicles from red blood cell products, a process mediated by β-integrin

(2016) Marleen Straat et al.   TRANSFUSION

Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria

(2016) Pierre-Yves Mantel et al.   Nature Communications

Diurnal Variations of Circulating Extracellular Vesicles Measured by Nano Flow Cytometry

(2016) Kirsty M. Danielson et al.   PLoS One

Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study

(2015) Y. F. Melman et al.   CIRCULATION

RNA-Seq identifies novel myocardial gene expression signatures of heart failure

(2015) Yichuan Liu et al.   GENOMICS

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(2015) Christoph Ott et al.   MOLECULAR MEDICINE

Extracellular Vesicles from Red Blood Cell Products Induce a Strong Pro-Inflammatory Host Response, Dependent on Both Numbers and Storage Duration

(2015) Marleen Straat et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

(2015) Margaret Alexander et al.   Nature Communications

Crosstalk between Red Blood Cells and the Immune System and Its Impact on Atherosclerosis

(2015) Brigitta Buttari et al.   Biomed Research International

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

(2015) Kirsten Ridder et al.   OncoImmunology

Role for Myosin-V Motor Proteins in the Selective Delivery of Kv Channel Isoforms to the Membrane Surface of Cardiac Myocytes

(2014) Sarah M. Schumacher-Bass et al.   CIRCULATION RESEARCH

Red blood cell and platelet microparticles in myocardial infarction patients treated with primary angioplasty

(2014) Georgios Giannopoulos et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

(2014) Claudia Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

A long noncoding RNA protects the heart from pathological hypertrophy

(2014) Pei Han et al.   NATURE

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

(2014) Kirsten Ridder et al.   PLOS BIOLOGY

Erythrocyte-Derived Microvesicles Amplify Systemic Inflammation by Thrombin-Dependent Activation of Complement

(2013) Daniel Zecher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro

(2013) A. Danesh et al.   BLOOD

The Immune System and the Remodeling Infarcted Heart

(2013) Nikolaos G. Frangogiannis   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation

(2013) Marc A Kerenyi et al.   eLife

Pathological Role of Serum- and Glucocorticoid-Regulated Kinase 1 in Adverse Ventricular Remodeling

(2012) Saumya Das et al.   CIRCULATION

Cognitive and brain changes associated with ischaemic heart disease and heart failure

(2012) Osvaldo P. Almeida et al.   EUROPEAN HEART JOURNAL

Cell fusion contributes to the rescue of apoptotic cardiomyocytes by bone marrow cells

(2012) Wei-Jian Yang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Microparticles from Stored Red Blood Cells Activate Neutrophils and Cause Lung Injury after Hemorrhage and Resuscitation

(2012) Ritha M. Belizaire et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?

(2012) Shayne A. Bellingham et al.   Frontiers in Physiology

Bone marrow mesenchymal stem cells for post-myocardial infarction cardiac repair: microRNAs as novel regulators

(2011) Zhuzhi Wen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ExoCarta 2012: database of exosomal proteins, RNA and lipids

(2011) S. Mathivanan et al.   NUCLEIC ACIDS RESEARCH

Procoagulant and prothrombotic activation of human erythrocytes by phosphatidic acid

(2010) Ji-Yoon Noh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sudden Cardiac Death Prediction and Prevention

(2010) Glenn I. Fishman et al.   CIRCULATION

Novel interactors and a role for supervillin in early cytokinesis

(2010) Tara C. Smith et al.   Cytoskeleton

Endothelial Microparticles Induce Inflammation in Acute Lung Injury

(2010) Keely L. Buesing et al.   JOURNAL OF SURGICAL RESEARCH

Establishing Primary Adult Fibroblast Cultures From Rodents

(2010) Andrei Seluanov et al.   Jove-Journal of Visualized Experiments

A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell-derived primitive hematopoiesis

(2009) O. Klimchenko et al.   BLOOD

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8+ T Lymphocytes

(2009) E. U. Wieckowski et al.   JOURNAL OF IMMUNOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

The possible role of red blood cell microvesicles in atherosclerosis

(2008) Arnon Blum   European Journal of Internal Medicine

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE