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Title
The Role of Connexin Hemichannels in Inflammatory Diseases
Authors
Keywords
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Journal
Biology-Basel
Volume 11, Issue 2, Pages 237
Publisher
MDPI AG
Online
2022-02-03
DOI
10.3390/biology11020237
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Note: Only part of the references are listed.- Release mechanisms of major DAMPs
- (2021) Atsushi Murao et al. APOPTOSIS
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- Mechanisms Underlying Connexin Hemichannel Activation in Disease
- (2021) Raf Van Campenhout et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Connexins in the Heart: Regulation, Function and Involvement in Cardiac Disease
- (2021) Antonio Rodríguez-Sinovas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Activation of Cx43 Hemichannels Induces the Generation of Ca2+ Oscillations in White Adipocytes and Stimulates Lipolysis
- (2021) Egor A. Turovsky et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting Cytokines, Pathogen-Associated Molecular Patterns, and Damage-Associated Molecular Patterns in Sepsis via Blood Purification
- (2021) Kazuhiro Moriyama et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cellular mechanisms of connexin-based inherited diseases
- (2021) Dale W. Laird et al. TRENDS IN CELL BIOLOGY
- Connexin channels modulation in pathophysiology and treatment of immune and inflammatory disorders
- (2021) Andrés Tittarelli BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Neutrophil and remnant clearance in immunity and inflammation
- (2021) Apurwa Singhal et al. IMMUNOLOGY
- Mechanisms of Connexin Regulating Peptides
- (2021) D. Ryan King et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Immune Modulation as a Key Mechanism for the Protective Effects of Remote Ischemic Conditioning After Stroke
- (2021) Sima Abbasi-Habashi et al. Frontiers in Neurology
- Pannexin-1 channel opening is critical for COVID-19 pathogenesis
- (2021) Ross Luu et al. iScience
- Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study
- (2020) Kristina E Rudd et al. LANCET
- Toll-like Receptors and the Control of Immunity
- (2020) Katherine A. Fitzgerald et al. CELL
- Targeting Inflammation Driven by HMGB1
- (2020) Huan Yang et al. Frontiers in Immunology
- LPS Induces Active HMGB1 Release From Hepatocytes Into Exosomes Through the Coordinated Activities of TLR4 and Caspase-11/GSDMD Signaling
- (2020) Wenbo Li et al. Frontiers in Immunology
- Therapeutic modulation of inflammasome pathways
- (2020) Dhruv Chauhan et al. IMMUNOLOGICAL REVIEWS
- Structural cells are key regulators of organ-specific immune responses
- (2020) Thomas Krausgruber et al. NATURE
- High‐mobility group box‐1 induces mechanical pain hypersensitivity through astrocytic connexin 43 via the Toll‐like receptor‐4/JNK signaling pathway
- (2020) Jiang Liu et al. SYNAPSE
- A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice
- (2020) Yuanyuan Kuang et al. EBioMedicine
- Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion
- (2020) Young Hun Kim et al. Autophagy
- Connexin Hemichannel Mimetic Peptide Attenuates Cortical Interneuron Loss and Perineuronal Net Disruption Following Cerebral Ischemia in Near-Term Fetal Sheep
- (2020) Panzao Yang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Connexin43 hemichannel block inhibits NLRP3 inflammasome activation in a human retinal explant model of diabetic retinopathy
- (2020) Henry H. Louie et al. EXPERIMENTAL EYE RESEARCH
- Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury
- (2020) Shuaiwei Wang et al. MEDIATORS OF INFLAMMATION
- Damage-Associated Molecular Patterns in Myocardial Infarction and Heart Transplantation: The Road to Translational Success
- (2020) Max J. M. Silvis et al. Frontiers in Immunology
- Uric acid preconditioning alleviated doxorubicin induced JNK activation and Cx43 phosphorylation associated cardiotoxicity via activation of AMPK-SHP2 signaling pathway
- (2020) Jiawei Wang et al. Annals of Translational Medicine
- Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke
- (2019) Moises Freitas-Andrade et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP3 inflammasome assembly
- (2019) Kaiwen W Chen et al. EMBO JOURNAL
- Connexin-43-dependent ATP release mediates macrophage activation during sepsis
- (2019) Michel Dosch et al. eLife
- The lipidated connexin mimetic peptide, SRPTEKT-Hdc, is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform
- (2019) Maura L. Cotter et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Global brain inflammation in stroke
- (2019) Kaibin Shi et al. LANCET NEUROLOGY
- Inflammation—The role of ATP in pre‐eclampsia
- (2019) Paul Fodor et al. MICROCIRCULATION
- DAMPs, PAMPs, and LAMPs in Immunity and Sterile Inflammation
- (2019) Joel Zindel et al. Annual Review of Pathology-Mechanisms of Disease
- Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock
- (2019) Tinneke Delvaeye et al. Scientific Reports
- DAMPs and NETs in Sepsis
- (2019) Naomi-Liza Denning et al. Frontiers in Immunology
- Lipidated connexin mimetic peptides potently inhibit gap junction-mediated Ca2+-wave propagation
- (2018) Maura L. Cotter et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Electrical synapses in mammalian CNS: Past eras, present focus and future directions
- (2018) James I. Nagy et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Gap junction gene and protein families: Connexins, innexins, and pannexins
- (2018) Eric C. Beyer et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The role of connexin and pannexin containing channels in the innate and acquired immune response
- (2018) Silvana Valdebenito et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Connexins and Pannexins in cerebral ischemia
- (2018) Yeri Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The inflammasome pathway is amplified and perpetuated in an autocrine manner through connexin43 hemichannel mediated ATP release
- (2018) Odunayo O. Mugisho et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
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- (2018) Ryan S. Tonkin et al. EXPERIMENTAL NEUROLOGY
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- (2018) Sara Crespo Yanguas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanisms of ATP Release by Inflammatory Cells
- (2018) Michel Dosch et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Xiang Yin et al. Journal of Neuroinflammation
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- (2018) Beilei Chen et al. BRAIN RESEARCH BULLETIN
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- (2017) Jonathon L. McClain et al. JOURNAL OF NEUROPHYSIOLOGY
- Systemic Administration of Connexin43 Mimetic Peptide Improves Functional Recovery after Traumatic Spinal Cord Injury in Adult Rats
- (2017) Yilin Mao et al. JOURNAL OF NEUROTRAUMA
- Role of Connexin and Pannexin containing channels in HIV infection and NeuroAIDS
- (2017) Shaily Malik et al. NEUROSCIENCE LETTERS
- Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels
- (2017) Yeri Kim et al. Neurotherapeutics
- Inhibitors of connexin and pannexin channels as potential therapeutics
- (2017) Joost Willebrords et al. PHARMACOLOGY & THERAPEUTICS
- Endotoxin-induced autocrine ATP signaling inhibits neutrophil chemotaxis through enhancing myosin light chain phosphorylation
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- (2017) Michaël Maes et al. TOXICOLOGY LETTERS
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- (2017) Joost Willebrords et al. Scientific Reports
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- (2017) Rana Tarzemany et al. Scientific Reports
- Effect of connexin 43 inhibition by the mimetic peptide Gap27 on corneal wound healing, inflammation and neovascularization
- (2016) Hossein Mostafa Elbadawy et al. BRITISH JOURNAL OF PHARMACOLOGY
- Connexins and their channels in inflammation
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- HIV-tat alters Connexin43 expression and trafficking in human astrocytes: role in NeuroAIDS
- (2016) Joan W. Berman et al. Journal of Neuroinflammation
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- (2016) Xing Liu et al. NATURE
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- (2015) Xiaojing Li et al. GLIA
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- (2015) Christina L. Grek et al. WOUND REPAIR AND REGENERATION
- Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells
- (2015) Dominique Thuringer et al. Oncotarget
- Selective Connexin43 Inhibition Prevents Isoproterenol-Induced Arrhythmias and Lethality in Muscular Dystrophy Mice
- (2015) J. Patrick Gonzalez et al. Scientific Reports
- Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells
- (2015) Ana Rosa Soares et al. Scientific Reports
- Intravitreal injection of lipoamino acid-modified connexin43 mimetic peptide enhances neuroprotection after retinal ischemia
- (2015) Ying-Shan Chen et al. Drug Delivery and Translational Research
- Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin
- (2015) Joseph D. Fontes et al. PLoS One
- Distinct permeation profiles of the connexin 30 and 43 hemichannels
- (2014) Daniel Bloch Hansen et al. FEBS LETTERS
- Differentiating connexin hemichannels and pannexin channels in cellular ATP release
- (2014) Alexander W. Lohman et al. FEBS LETTERS
- Regulation of Hemichannels and Gap Junction Channels by Cytokines in Antigen-Presenting Cells
- (2014) Pablo J. Sáez et al. MEDIATORS OF INFLAMMATION
- Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity
- (2014) Kristin Westphalen et al. NATURE
- Impact of the Controlled Release of a Connexin 43 Peptide on Corneal Wound Closure in an STZ Model of Type I Diabetes
- (2014) Keith Moore et al. PLoS One
- Connexin Hemichannel Blockade Is Neuroprotective after Asphyxia in Preterm Fetal Sheep
- (2014) Joanne O. Davidson et al. PLoS One
- JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation
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- Connexin hemichannel blockade is neuroprotective after, but not during, global cerebral ischemia in near-term fetal sheep
- (2013) J.O. Davidson et al. EXPERIMENTAL NEUROLOGY
- Unknown
- (2013) Wei Li et al. MOLECULAR MEDICINE
- Antibodies targeting extracellular domain of connexins for studies of hemichannels
- (2013) Manuel A. Riquelme et al. NEUROPHARMACOLOGY
- Connexin targeting peptides as inhibitors of voltage- and intracellular Ca2+-triggered Cx43 hemichannel opening
- (2013) Nan Wang et al. NEUROPHARMACOLOGY
- Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury
- (2013) Simon J. O’Carroll et al. NEUROSCIENCE RESEARCH
- ATP Releasing Connexin 30 Hemichannels Mediate Flow-Induced Calcium Signaling in the Collecting Duct
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- Endothelial connexin43 mediates acid-induced increases in pulmonary microvascular permeability
- (2012) Kaushik Parthasarathi AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation
- (2012) Nan Wang et al. BASIC RESEARCH IN CARDIOLOGY
- Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury
- (2012) Nan Wang et al. BASIC RESEARCH IN CARDIOLOGY
- Paracrine signaling through plasma membrane hemichannels
- (2012) Nan Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Connexins in atherosclerosis
- (2012) Anna Pfenniger et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Connexin43 mimetic peptide reduces vascular leak and retinal ganglion cell death following retinal ischaemia
- (2012) Helen V. Danesh-Meyer et al. BRAIN
- Single intravenous low-dose injections of connexin 43 mimetic peptides protect ischemic heart in vivo against myocardial infarction
- (2012) Ghayda Hawat et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Novel role of PKR in inflammasome activation and HMGB1 release
- (2012) Ben Lu et al. NATURE
- Glial connexin expression and function in the context of Alzheimer's disease
- (2011) Annette Koulakoff et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Human Connexin30.2/31.3 (GJC3) does not Form Functional Gap Junction Channels but Causes Enhanced ATP Release in HeLa Cells
- (2011) Wei-Guang Liang et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Ischemia Induces Closure of Gap Junctional Channels and Opening of Hemichannels in Heart-derived Cells and Tissue
- (2011) David Johansen et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- A Peptide Mimetic of the Connexin43 Carboxyl Terminus Reduces Gap Junction Remodeling and Induced Arrhythmia Following Ventricular Injury
- (2011) Michael P. O'Quinn et al. CIRCULATION RESEARCH
- Connexins as therapeutic targets in lung disease
- (2011) Davide Losa et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- The perinexus: A new feature of Cx43 gap junction organization
- (2011) Joshua Matthew Rhett et al. HEART RHYTHM
- ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
- (2011) Juan A. Orellana et al. JOURNAL OF NEUROCHEMISTRY
- Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity
- (2010) Raf Ponsaerts et al. FASEB JOURNAL
- The Connexin43 C-Terminal Region Mediates Neuroprotection During Stroke
- (2010) Michael G. Kozoriz et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Connexin 43 mimetic peptide Gap26 confers protection to intact heart against myocardial ischemia injury
- (2010) Ghayda Hawat et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Glycosylation Regulates Pannexin Intermixing and Cellular Localization
- (2009) Silvia Penuela et al. MOLECULAR BIOLOGY OF THE CELL
- Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding
- (2009) Gautam S Ghatnekar et al. Regenerative Medicine
- Cross-Talk Between Pulmonary Injury, Oxidant Stress, and Gap Junctional Communication
- (2008) Latoya N. Johnson et al. ANTIOXIDANTS & REDOX SIGNALING
- Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model
- (2008) E Decrock et al. CELL DEATH AND DIFFERENTIATION
- ATP release by cardiac myocytes in a simulated ischaemia model
- (2008) Thomas C. Clarke et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Enhancing action by sulfated hyaluronan on connexin-26, -32, and -43 gene expressions during the culture of normal human astrocytes
- (2008) Saifuddin Ahmed et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- ATP Release from Vascular Endothelia Occurs Across Cx43 Hemichannels and Is Attenuated during Hypoxia
- (2008) Marion Faigle et al. PLoS One
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