Breast Cancer Cell Subtypes Display Different Metabolic Phenotypes That Correlate with Their Clinical Classification

Chimeric Drug Design with a Noncharged Carrier for Mitochondrial Delivery

(2021) Consuelo Ripoll et al.   Pharmaceutics

Mitochondrial pH Nanosensors for Metabolic Profiling of Breast Cancer Cell Lines

(2020) Consuelo Ripoll et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glucose Metabolic Reprogramming of ER Breast Cancer in Acquired Resistance to the CDK4/6 Inhibitor Palbociclib+

(2020) Nicla Lorito et al.   Cells

Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways

(2019) Dongya Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of Pentose Phosphate Pathway-Related Proteins in Breast Cancer

(2018) Junjeong Choi et al.   DISEASE MARKERS

Glutamine‐utilizing transaminases are a metabolic vulnerability of TAZ/YAP‐activated cancer cells

(2018) Chih‐Sheng Yang et al.   EMBO REPORTS

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

(2018) Xinxin Peng et al.   Cell Reports

Crosstalk between Estrogen Signaling and Breast Cancer Metabolism

(2018) Eylem Kulkoyluoglu-Cotul et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metabotypes of breast cancer cell lines revealed by non-targeted metabolomics

(2017) Sébastien Dubuis et al.   METABOLIC ENGINEERING

Deciphering metabolic rewiring in breast cancer subtypes

(2017) Martin P. Ogrodzinski et al.   Translational Research

Phenformin inhibits growth and epithelial-mesenchymal transition of ErbB2-overexpressing breast cancer cells through targeting the IGF1R pathway

(2017) Zhiying Guo et al.   Oncotarget

Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors

(2017) Satoshi Kitazawa et al.   Oncotarget

Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton

(2016) Hai Hu et al.   CELL

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

(2016) Dan Y. Gui et al.   Cell Metabolism

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth

(2016) Lifeng Yang et al.   Cell Metabolism

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells

(2016) Jonathan L. Coloff et al.   Cell Metabolism

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells

(2016) Aaron M. Hosios et al.   DEVELOPMENTAL CELL

Expanding the view of breast cancer metabolism: Promising molecular targets and therapeutic opportunities

(2016) John P. Harrelson et al.   PHARMACOLOGY & THERAPEUTICS

Combined inhibition of glycolysis and AMPK induces synergistic breast cancer cell killing

(2015) Yong Wu et al.   BREAST CANCER RESEARCH AND TREATMENT

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

(2015) Kıvanç Birsoy et al.   CELL

Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate

(2015) P. Korangath et al.   CLINICAL CANCER RESEARCH

Metabolic profiling of breast cancer: Differences in central metabolism between subtypes of breast cancer cell lines

(2015) Lucas Willmann et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

(2015) Saverio Tardito et al.   NATURE CELL BIOLOGY

Differential Expression of Lipid Metabolism-Related Proteins in Different Breast Cancer Subtypes

(2015) Sewha Kim et al.   PLoS One

Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells

(2015) Zhao Liu et al.   PLoS One

Glutamate enrichment as new diagnostic opportunity in breast cancer

(2014) Jan Budczies et al.   INTERNATIONAL JOURNAL OF CANCER

Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

(2014) M. I. Gross et al.   MOLECULAR CANCER THERAPEUTICS

Differential Expression of Enzymes Associated with Serine/Glycine Metabolism in Different Breast Cancer Subtypes

(2014) Sang Kyum Kim et al.   PLoS One

Tumor-dependent increase of serum amino acid levels in breast cancer patients has diagnostic potential and correlates with molecular tumor subtypes

(2013) Isabel Poschke et al.   Journal of Translational Medicine

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

Epigallocatechin-3-Gallate Inhibits Stem-Like Inflammatory Breast Cancer Cells

(2013) Nora D. Mineva et al.   PLoS One

Phenformin as prophylaxis and therapy in breast cancer xenografts

(2012) M V C L Appleyard et al.   BRITISH JOURNAL OF CANCER

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

(2012) Anne Le et al.   Cell Metabolism

Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis

(2012) Dania Daye et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer

(2012) Barbara Chaneton et al.   TRENDS IN BIOCHEMICAL SCIENCES

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

(2011) T. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists

(2010) Sunil Badve et al.   MODERN PATHOLOGY

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells

(2010) M. G. Vander Heiden et al.   SCIENCE

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

Targeting the PI3K signaling pathway in cancer

(2009) Kwok-Kin Wong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

(2008) D. R. Wise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA