Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta

Biomechanical Consequences of Compromised Elastic Fiber Integrity and Matrix Cross-Linking on Abdominal Aortic Aneurysmal Enlargement

(2021) D. Weiss et al.   Acta Biomaterialia

Evolving structure-function relations during aortic maturation and aging revealed by multiphoton microscopy

(2021) Cristina Cavinato et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Marfan syndrome

(2021) Dianna M. Milewicz et al.   Nature Reviews Disease Primers

Prosthetic aortic graft replacement of the ascending thoracic aorta alters biomechanics of the native descending aorta as assessed by transthoracic echocardiography

(2020) Maria C. Palumbo et al.   PLoS One

Developmental origins of mechanical homeostasis in the aorta

(2020) Sae‐Il Murtada et al.   DEVELOPMENTAL DYNAMICS

Elastic fibers and biomechanics of the aorta: Insights from mouse studies

(2019) Hiromi Yanagisawa et al.   MATRIX BIOLOGY

From genetics to response to injury: vascular smooth muscle cells in aneurysms and dissections of the ascending aorta

(2018) Jean-Baptiste Michel et al.   CARDIOVASCULAR RESEARCH

Local variations in material and structural properties characterize murine thoracic aortic aneurysm mechanics

(2018) Matthew R. Bersi et al.   Biomechanics and Modeling in Mechanobiology

Combining in vivo and in vitro biomechanical data reveals key roles of perivascular tethering in central artery function

(2018) Jacopo Ferruzzi et al.   PLoS One

Central artery stiffness and thoracic aortopathy

(2018) J. D. Humphrey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Micromechanics of elastic lamellae: unravelling the role of structural inhomogeneity in multi-scale arterial mechanics

(2018) Xunjie Yu et al.   Journal of the Royal Society Interface

Comparison of 10 murine models reveals a distinct biomechanical phenotype in thoracic aortic aneurysms

(2017) C. Bellini et al.   Journal of the Royal Society Interface

High-Resolution Morphological Approach to Analyse Elastic Laminae Injuries of the Ascending Aorta in a Murine Model of Marfan Syndrome

(2017) Júlia López-Guimet et al.   Scientific Reports

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases — nomenclature and diagnostic criteria

(2016) Marc K. Halushka et al.   CARDIOVASCULAR PATHOLOGY

Differential ascending and descending aortic mechanics parallel aneurysmal propensity in a mouse model of Marfan syndrome

(2016) C. Bellini et al.   JOURNAL OF BIOMECHANICS

Dimorphic Effects of Transforming Growth Factor-β Signaling During Aortic Aneurysm Progression in Mice Suggest a Combinatorial Therapy for Marfan SyndromeSignificance

(2015) Jason R. Cook et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Mechanotransduction in Vascular Biology: Focus on Thoracic Aortic Aneurysms and Dissections

(2015) J. D. Humphrey et al.   CIRCULATION RESEARCH

Decreased Elastic Energy Storage, Not Increased Material Stiffness, Characterizes Central Artery Dysfunction in Fibulin-5 Deficiency Independent of Sex

(2015) J. Ferruzzi et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Quantification of aortic and cutaneous elastin and collagen morphology in Marfan syndrome by multiphoton microscopy

(2014) Jason Z. Cui et al.   JOURNAL OF STRUCTURAL BIOLOGY

IL‐6 Regulates Extracellular Matrix Remodeling Associated With Aortic Dilation in a Fibrillin‐1 Hypomorphic mgR/mgR Mouse Model of Severe Marfan Syndrome

(2014) Xiaoxi Ju et al.   Journal of the American Heart Association

A Microstructurally Motivated Model of Arterial Wall Mechanics with Mechanobiological Implications

(2013) C. Bellini et al.   ANNALS OF BIOMEDICAL ENGINEERING

TANGO: a generic tool for high-throughput 3D image analysis for studying nuclear organization

(2013) Jean Ollion et al.   BIOINFORMATICS

Quantification of regional differences in aortic stiffness in the aging human

(2013) S. Roccabianca et al.   Journal of the Mechanical Behavior of Biomedical Materials

The fibrillin-1 hypomorphic mgR/mgR murine model of Marfan syndrome shows severe elastolysis in all segments of the aorta

(2013) Simon Schwill et al.   JOURNAL OF VASCULAR SURGERY

Progressive structural and biomechanical changes in elastin degraded aorta

(2012) Ming-Jay Chow et al.   Biomechanics and Modeling in Mechanobiology

Matrix-dependent perturbation of TGFβ signaling and disease

(2012) Jefferson J. Doyle et al.   FEBS LETTERS

Mechanical assessment of elastin integrity in fibrillin-1-deficient carotid arteries: implications for Marfan syndrome

(2011) Jacopo Ferruzzi et al.   CARDIOVASCULAR RESEARCH

Altered tissue behavior of a non-aneurysmal descending thoracic aorta in the mouse model of Marfan syndrome

(2011) Darren Haskett et al.   CELL AND TISSUE RESEARCH

Fibrillin-1 genetic deficiency leads to pathological ageing of arteries in mice

(2010) Boubacar Mariko et al.   JOURNAL OF PATHOLOGY

Mechanics of Carotid Arteries in a Mouse Model of Marfan Syndrome

(2009) J. F. Eberth et al.   ANNALS OF BIOMEDICAL ENGINEERING

Discrete Contributions of Elastic Fiber Components to Arterial Development and Mechanical Compliance

(2009) Luca Carta et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Origin of axial prestretch and residual stress in arteries

(2009) L. Cardamone et al.   Biomechanics and Modeling in Mechanobiology