Comparison of 10 murine models reveals a distinct biomechanical phenotype in thoracic aortic aneurysms

Biomechanical Phenotyping of the Murine Aorta: What Is the Best Control?

(2017) C. Bellini et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

A hidden structural vulnerability in the thrombospondin-2 deficient aorta increases the propensity to intramural delamination

(2017) C. Bellini et al.   Journal of the Mechanical Behavior of Biomedical Materials

Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix PropertiesSignificance

(2016) Jacopo Ferruzzi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Decreased Aortic Elasticity in Children With Marfan Syndrome or Loeys-Dietz Syndrome

(2016) Yohei Akazawa et al.   CIRCULATION JOURNAL

Excessive Adventitial Remodeling Leads to Early Aortic Maladaptation in Angiotensin-Induced HypertensionNovelty and Significance

(2016) Matthew R. Bersi et al.   HYPERTENSION

Differential ascending and descending aortic mechanics parallel aneurysmal propensity in a mouse model of Marfan syndrome

(2016) C. Bellini et al.   JOURNAL OF BIOMECHANICS

Dimorphic Effects of Transforming Growth Factor-β Signaling During Aortic Aneurysm Progression in Mice Suggest a Combinatorial Therapy for Marfan SyndromeSignificance

(2015) Jason R. Cook et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Mechanotransduction in Vascular Biology: Focus on Thoracic Aortic Aneurysms and Dissections

(2015) J. D. Humphrey et al.   CIRCULATION RESEARCH

Decreased Elastic Energy Storage, Not Increased Material Stiffness, Characterizes Central Artery Dysfunction in Fibulin-5 Deficiency Independent of Sex

(2015) J. Ferruzzi et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Myh11R247C/R247C mutations increase thoracic aorta vulnerability to intramural damage despite a general biomechanical adaptivity

(2015) Chiara Bellini et al.   JOURNAL OF BIOMECHANICS

Human thoracic and abdominal aortic aneurysmal tissues: Damage experiments, statistical analysis and constitutive modeling

(2015) David M. Pierce et al.   Journal of the Mechanical Behavior of Biomedical Materials

Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice

(2015) Yoshito Yamashiro et al.   Science Signaling

Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice

(2015) Yoshito Yamashiro et al.   Science Signaling

Consistent Biomechanical Phenotyping of Common Carotid Arteries from Seven Genetic, Pharmacological, and Surgical Mouse Models

(2014) M. R. Bersi et al.   ANNALS OF BIOMEDICAL ENGINEERING

Mechano-biology in the thoracic aortic aneurysm: a review and case study

(2014) G. Martufi et al.   Biomechanics and Modeling in Mechanobiology

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis

(2014) Wei Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Dysfunctional Mechanosensing in Aneurysms

(2014) J. D. Humphrey et al.   SCIENCE

The Genetic Basis of Aortic Aneurysm

(2014) M. E. Lindsay et al.   Cold Spring Harbor Perspectives in Medicine

Biomechanical Properties of Human Ascending Thoracic Aortic Aneurysms

(2013) Ali N. Azadani et al.   ANNALS OF THORACIC SURGERY

Rare, Nonsynonymous Variant in the Smooth Muscle-Specific Isoform of Myosin Heavy Chain, MYH11 , R247C, Alters Force Generation in the Aorta and Phenotype of Smooth Muscle Cells

(2012) Shao-Qing Kuang et al.   CIRCULATION RESEARCH

Mechanical behaviour and rupture of normal and pathological human ascending aortic wall

(2012) C. M. García-Herrera et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Parametric study of effects of collagen turnover on the natural history of abdominal aortic aneurysms

(2012) J. S. Wilson et al.   PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Biomechanical response of ascending thoracic aortic aneurysms: association with structural remodelling

(2011) Dimitrios P. Sokolis et al.   COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE−/−mice

(2010) Alan Daugherty et al.   CLINICAL SCIENCE

Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2+/− mice

(2010) Jiumei Cao et al.   HUMAN MOLECULAR GENETICS

Fibulin-4 Deficiency Results in Ascending Aortic Aneurysms

(2009) Jianbin Huang et al.   CIRCULATION RESEARCH

An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice

(2009) Brian C. Tieu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular and molecular mechanisms of thoracic aortic aneurysms

(2009) Ismail El-Hamamsy et al.   Nature Reviews Cardiology

Vascular Extracellular Matrix and Arterial Mechanics

(2009) Jessica E. Wagenseil et al.   PHYSIOLOGICAL REVIEWS

Genetic Basis of Thoracic Aortic Aneurysms and Dissections: Focus on Smooth Muscle Cell Contractile Dysfunction

(2008) Dianna M. Milewicz et al.   Annual Review of Genomics and Human Genetics

Thoracic Aortic Aneurysm: Reading the Enemy's Playbook

(2008) John A. Elefteriades   CURRENT PROBLEMS IN CARDIOLOGY

Fundamental role of axial stress in compensatory adaptations by arteries

(2008) J.D. Humphrey et al.   JOURNAL OF BIOMECHANICS