Extracellular Vesicle Delivery of Neferine for the Attenuation of Neurodegenerative Disease Proteins and Motor Deficit in an Alzheimer’s Disease Mouse Model

Insights into the antitumor mechanism of ginsenosides Rg3

(2021) Zongyu Liu et al.   MOLECULAR BIOLOGY REPORTS

Microfluidic Tools for Enhanced Characterization of Therapeutic Stem Cells and Prediction of Their Potential Antimicrobial Secretome

(2021) Pasquale Marrazzo et al.   Antibiotics-Basel

Ginsenoside Rg3 exerts a neuroprotective effect in rotenone-induced Parkinson's disease mice via its anti-oxidative properties

(2021) Yingjie Han et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Breaking the selectivity-uptake trade-off of photoimmunoconjugates with nanoliposomal irinotecan for synergistic multi-tier cancer targeting

(2020) Barry J. Liang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Autophagy and post-ischemic conditioning in retinal ischemia

(2020) Biji Mathew et al.   Autophagy

Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease

(2020) Jaydeep Sidhaye et al.   CELL DEATH AND DIFFERENTIATION

The mechanistic target of rapamycin (mTOR): Novel Considerations as an Antiviral Treatment and Possibilities for COVID-19

(2020) Kenneth Maiese   CURRENT NEUROVASCULAR RESEARCH

Brain Derived Exosomes Are a Double-Edged Sword in Alzheimer’s Disease

(2020) Zhiqi Song et al.   Frontiers in Molecular Neuroscience

Ultrasound Assisted Exosomal Delivery of Tissue Responsive mRNA for Enhanced Efficacy and Minimized Off-Target Effects

(2020) Wenqi Sun et al.   Molecular Therapy-Nucleic Acids

The New Application of UHPLC-DAD-TOF/MS in Identification of Inhibitors on β-Amyloid Fibrillation From Scutellaria baicalensis

(2019) Lu Yu et al.   Frontiers in Pharmacology

Ginsenoside Rb1 prevents MPTP-induced changes in hippocampal memory via regulation of the α-synuclein/PSD-95 pathway

(2019) Shaogang Qu et al.   Aging-US

New insight into isolation, identification techniques and medical applications of exosomes

(2019) Xiao-Xia Yang et al.   JOURNAL OF CONTROLLED RELEASE

Human umbilical cord mesenchymal stem cells derived-exosomes in diseases treatment

(2019) Yoda Yaghoubi et al.   LIFE SCIENCES

Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature

(2019) Kenneth W. Witwer et al.   Journal of Extracellular Vesicles

Baicalein attenuates impairment of hepatic lysosomal acidification induced by high fat diet via maintaining V-ATPase assembly

(2019) Xinhong Zhu et al.   FOOD AND CHEMICAL TOXICOLOGY

Amyloid-β and Tau in Alzheimer’s Disease: Novel Pathomechanisms and Non-Pharmacological Treatment Strategies

(2018) Rebecca M. Nisbet et al.   JOURNAL OF ALZHEIMERS DISEASE

Autophagy regulates exosomal release of prions in neuronal cells

(2018) Basant A. Abdulrahman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological benefits of neferine - A comprehensive review

(2018) Shibu Marthandam Asokan et al.   LIFE SCIENCES

Efficient RNA drug delivery using red blood cell extracellular vesicles

(2018) Waqas Muhammad Usman et al.   Nature Communications

Pharmacokinetics and Bioavailability Enhancement of Baicalin: A Review

(2018) Ting Huang et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Plasma pharmacokinetics of isorhapontigenin, a novel derivative of stilbenes, in mice by LC-MS/MS method

(2018) Ting-Ting Zhang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Exosome as a Novel Shuttle for Delivery of Therapeutics across Biological Barriers

(2018) Chandan Kanta Das et al.   MOLECULAR PHARMACEUTICS

Disruption of Circulating Extracellular Vesicles as a Novel Therapeutic Strategy against Cancer Metastasis

(2017) Nao Nishida-Aoki et al.   MOLECULAR THERAPY

Ginsenoside Rb1 for Myocardial Ischemia/Reperfusion Injury: Preclinical Evidence and Possible Mechanisms

(2017) Qun Zheng et al.   Oxidative Medicine and Cellular Longevity

Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice

(2017) An-Guo Wu et al.   PHARMACOLOGICAL RESEARCH

Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

(2017) Michael P. Plebanek et al.   Nature Communications

Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation

(2017) Christine Xue et al.   Royal Society Open Science

Development and validation of a quantification method for oleanolic acid and hederagenin in rat plasma: application to the pharmacokinetic study

(2016) Heng Zhang et al.   BIOMEDICAL CHROMATOGRAPHY

Q&A: What are exosomes, exactly?

(2016) James R. Edgar   BMC BIOLOGY

An overview of rapamycin: from discovery to future perspectives

(2016) Young Ji Yoo et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Extracellular vesicles round off communication in the nervous system

(2016) Vivian Budnik et al.   NATURE REVIEWS NEUROSCIENCE

Exosomes isolation and characterization in serum is feasible in non-small cell lung cancer patients: critical analysis of evidence and potential role in clinical practice

(2016) Simona Taverna et al.   Oncotarget

Experimental Study of Antiatherosclerosis Effects with Hederagenin in Rats

(2015) Su-Hong Lu et al.   Evidence-based Complementary and Alternative Medicine

Exosomes as drug delivery vehicles for Parkinson's disease therapy

(2015) Matthew J. Haney et al.   JOURNAL OF CONTROLLED RELEASE

Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins

(2015) Gregor Fuhrmann et al.   JOURNAL OF CONTROLLED RELEASE

Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells

(2015) Heikki Saari et al.   JOURNAL OF CONTROLLED RELEASE

Using exosomes, naturally-equipped nanocarriers, for drug delivery

(2015) Elena V. Batrakova et al.   JOURNAL OF CONTROLLED RELEASE

Neferine Attenuates the Protein Level and Toxicity of Mutant Huntingtin in PC-12 Cells via Induction of Autophagy

(2015) Vincent Wong et al.   MOLECULES

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia

(2015) Insaf Bahrini et al.   Scientific Reports

Assessment of baicalin in mouse blood by monoclonal antibody-based icELISA

(2014) Yan Zhao et al.   BIOMEDICAL CHROMATOGRAPHY

A potential function for neuronal exosomes: Sequestering intracerebral amyloid-β peptide

(2014) Kohei Yuyama et al.   FEBS LETTERS

Rapamycin Plays a Neuroprotective Effect after Spinal Cord Injury via Anti-Inflammatory Effects

(2014) Yu Song et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery

(2014) Luisa Pascucci et al.   JOURNAL OF CONTROLLED RELEASE

Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery

(2012) Ronne Wee Yeh Yeo et al.   ADVANCED DRUG DELIVERY REVIEWS

Drug Transport across the Blood–Brain Barrier

(2012) William M Pardridge   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Triterpene acids from euscaphis and assessment of their cytotoxic and anti-no activities

(2012) LJ Zhang et al.   PLANTA MEDICA

Baicalein Inhibits Formation of α-Synuclein Oligomers within Living Cells and Prevents Aβ Peptide Fibrillation and Oligomerisation

(2011) Jia-Hong Lu et al.   CHEMBIOCHEM

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY