Vitamin D3 Prevents the Deleterious Effects of Testicular Torsion on Testis by Targeting miRNA-145 and ADAM17: In Silico and In Vivo Study

Testicular torsion: its effect on autoimmunisation, pituitary–testis axis and correlation with primary gonadal dysfunction in boys

(2021) Paweł Osemlak et al.   PEDIATRIC RESEARCH

New Mononuclear and Binuclear Cu(II), Co(II), Ni(II), and Zn(II) Thiosemicarbazone Complexes with Potential Biological Activity: Antimicrobial and Molecular Docking Study

(2021) Ahmed Gaber et al.   MOLECULES

Novel N-bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis, in vitro and in silico studies

(2021) Islam H El Azab et al.   Future Medicinal Chemistry

Impacts of Immunometabolism on Male Reproduction

(2021) Lijun Ye et al.   Frontiers in Immunology

Vitamin D status and systemic redox biomarkers in adults with obesity

(2021) Somayyeh Asghari et al.   Clinical Nutrition ESPEN

Novel Papaverine Metal Complexes with Potential Anticancer Activities

(2020) Ahmed Gaber et al.   MOLECULES

Function of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment

(2019) Dong Ye et al.   Cancer Management and Research

Differential expression of miR-23a/b-3p and its target genes in male patients with subfertility

(2019) Masood Abu-Halima et al.   FERTILITY AND STERILITY

Vitamin D Improves Nitric Oxide-Dependent Vasodilation in Adipose Tissue Arterioles from Bariatric Surgery Patients

(2019) Abeer M. Mahmoud et al.   Nutrients

Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model

(2019) Malsawmhriatzuala Jeremy et al.   Scientific Reports

Age-associated expression of vitamin D receptor and vitamin D-metabolizing enzymes in the male reproductive tract and sperm of Hu sheep

(2018) Xiaolei Yao et al.   ANIMAL REPRODUCTION SCIENCE

Vitamin D: Classic and Novel Actions

(2018) Ángel Gil et al.   ANNALS OF NUTRITION AND METABOLISM

The Ameliorating Effect of Berberine-Rich Fraction against Gossypol-Induced Testicular Inflammation and Oxidative Stress

(2018) Samar R. Saleh et al.   Oxidative Medicine and Cellular Longevity

Direction of Rotation in Testicular Torsion and Identification of Predictors of Testicular Salvage

(2018) Todd Yecies et al.   UROLOGY

Microcirculatory effects of sildenafil in experimental testicular torsion in rats

(2018) Márton Oroszi et al.   WORLD JOURNAL OF UROLOGY

Vitamin D alleviates lead induced renal and testicular injuries by immunomodulatory and antioxidant mechanisms in rats

(2018) Mohammad A. BaSalamah et al.   Scientific Reports

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

(2018) Jacob O'Brien et al.   Frontiers in Endocrinology

Effects of Vitamin D Supplementation on Semen Quality, Reproductive Hormones, and Live Birth Rate: A Randomized Clinical Trial

(2017) Martin Blomberg Jensen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Probucol Reduces Testicular Torsion/Detorsion-Induced Ischemia/Reperfusion Injury in Rats

(2017) Si-Ming Wei et al.   Oxidative Medicine and Cellular Longevity

Medical perspective in testicular ischemia-reperfusion injury

(2017) Salvatore Arena et al.   Experimental and Therapeutic Medicine

Hypoxia reduces testosterone synthesis in mouse Leydig cells by inhibiting NRF1-activated StAR expression

(2017) Xueting Wang et al.   Oncotarget

Protective effects of hesperidin in experimental testicular ischemia/reperfusion injury in rats

(2016) Emrah Celik et al.   Archives of Medical Science

1,25(OH) 2 D 3 inhibits oxidative stress and monocyte adhesion by mediating the upregulation of GCLC and GSH in endothelial cells treated with acetoacetate (ketosis)

(2016) Preeti Kanikarla-Marie et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

MiR-145, a microRNA targeting ADAM17, inhibits the invasion and migration of nasopharyngeal carcinoma cells

(2015) Jing Wu et al.   EXPERIMENTAL CELL RESEARCH

The role of vitamin D in the carcinogenesis of breast and ovarian cancer

(2015) Marek Grabiec et al.   Ginekologia Polska

MicroRNA-145 Targets the Metalloprotease ADAM17 and Is Suppressed in Renal Cell Carcinoma Patients

(2015) Kai Doberstein et al.   NEOPLASIA

The biochemical effects of ischemia-reperfusion injury in the ipsilateral and contralateral testes of rats and the protective role of melatonin

(2014) BekirS Parlaktas et al.   ASIAN JOURNAL OF ANDROLOGY

MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma

(2014) YUWU LIU et al.   ONCOLOGY REPORTS

The regulation of spermatogenesis by androgens

(2014) Lee B. Smith et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Beneficial Effect of Nifedipine on Testicular Torsion-detorsion Injury in Rats

(2014) Jakov Meštrović et al.   UROLOGY

Crystal Structure of Sphingosine Kinase 1 with PF-543

(2014) Jing Wang et al.   ACS Medicinal Chemistry Letters

Membrane-Proximal Domain of a Disintegrin and Metalloprotease-17 Represents the Putative Molecular Switch of Its Shedding Activity Operated by Protein-disulfide Isomerase

(2013) Stefan Düsterhöft et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interleukin 10 Reduces Testicular Damage in Experimental Testicular Ischemia/Reperfusion Injury

(2013) Hulya Ozturk et al.   UROLOGY

MECHANISMS IN ENDOCRINOLOGY: Vitamin D and fertility: a systematic review

(2012) E. Lerchbaum et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The Hypoxic Testicle: Physiology and Pathophysiology

(2012) Juan G. Reyes et al.   Oxidative Medicine and Cellular Longevity

2-(2-Aminothiazol-4-yl)pyrrolidine-based tartrate diamides as potent, selective and orally bioavailable TACE inhibitors

(2011) Chaoyang Dai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Intratesticular pressure after testicular torsion as a predictor of subsequent spermatogenesis: a rat model

(2011) Yoshinobu Moritoki et al.   BJU INTERNATIONAL

Nicorandil ameliorates ischaemia-reperfusion injury in the rat kidney

(2011) Shogo Shimizu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protective Effects of Melatonin on Testicular Torsion and Detorsion Damage in Sprague-Dawley Rats

(2011) Ayfer Aktas et al.   INTERNATIONAL JOURNAL OF MORPHOLOGY

Biaryl substituted hydantoin compounds as TACE inhibitors

(2010) Wensheng Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure and activity relationships of tartrate-based TACE inhibitors

(2010) Dansu Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effect of Vitamin D Supplementation on Testosterone Levels in Men

(2010) S. Pilz et al.   HORMONE AND METABOLIC RESEARCH

Late hormonal function after testicular torsion

(2010) Carmelo Romeo et al.   JOURNAL OF PEDIATRIC SURGERY

Preventive Effects of Cyclosporine A Combined With Prednisolone and Melatonin on Contralateral Testicular Damage After Ipsilateral Torsion-Detorsion in Pubertal and Adult Rats

(2010) Seong Jin Jeong et al.   JOURNAL OF UROLOGY

TACE/ADAM17 is involved in germ cell apoptosis during rat spermatogenesis

(2010) Carlos Lizama et al.   REPRODUCTION

Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-α converting enzyme (TACE) inhibitors

(2009) Kaapjoo Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The discovery of novel tartrate-based TNF-α converting enzyme (TACE) inhibitors

(2009) Kristin E. Rosner et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion

(2009) A. Brill et al.   CARDIOVASCULAR RESEARCH

Discovery of novel hydroxamates as highly potent tumor necrosis factor-α converting enzyme inhibitors. Part II: Optimization of the S3′ pocket

(2008) Robert D. Mazzola et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of novel spirocyclopropyl hydroxamate and carboxylate compounds as TACE inhibitors

(2008) Zhuyan Guo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

(2008) Roger Bouillon et al.   ENDOCRINE REVIEWS

Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke

(2008) Alberto Izzotti et al.   FASEB JOURNAL

Oxidative Stress: A Common Factor in Testicular Dysfunction

(2008) T. T. Turner et al.   JOURNAL OF ANDROLOGY

Structural Determinants of the ADAM Inhibition by TIMP-3: Crystal Structure of the TACE-N-TIMP-3 Complex

(2008) Magdalena Wisniewska et al.   JOURNAL OF MOLECULAR BIOLOGY

Novel thiol-based TACE inhibitors. Part 2: Rational design, synthesis, and SAR of thiol-containing aryl sulfones

(2007) Upul K. Bandarage et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS