Gut Dysbiosis and Immune System in Atherosclerotic Cardiovascular Disease (ACVD)

The promise and challenges of RNA-targeted therapeutics in preventive cardiology

(2021) Benoit J Arsenault   EUROPEAN HEART JOURNAL

Nucleic Acid–Based Therapies for Atherosclerosis

(2020) Petri Mäkinen et al.   Current Atherosclerosis Reports

The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids

(2020) Sarah Ducastel et al.   Scientific Reports

Polysaccharides from Polygonatum kingianum improve glucose and lipid metabolism in rats fed a high fat diet

(2020) Wen Gu et al.   BIOMEDICINE & PHARMACOTHERAPY

Cross-omics analysis revealed gut microbiome-related metabolic pathways underlying atherosclerosis development after antibiotics treatment

(2020) Ben Arpad Kappel et al.   Molecular Metabolism

Gut Microbiota and Immune System Interactions

(2020) Ji Youn Yoo et al.   Microorganisms

The Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

(2019) Hendrik Bartolomaeus et al.   CIRCULATION

Immune Disorder in Atherosclerotic Cardiovascular Disease　― Clinical Implications of Using Circulating T-Cell Subsets as Biomarkers ―

(2019) Rajib Neupane et al.   CIRCULATION JOURNAL

Lack of Ability to Present Antigens on Major Histocompatibility Complex Class II Molecules Aggravates Atherosclerosis in ApoE −/− Mice

(2019) Maria Wigren et al.   CIRCULATION

Improvement of Gut Microbiota by Inhibition of P38 Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Rats with Severe Acute Pancreatitis

(2019) You-Dong Wan et al.   MEDICAL SCIENCE MONITOR

Glucagon-like peptide 1 (GLP-1)

(2019) T.D. Müller et al.   Molecular Metabolism

Both gut microbiota and cytokines act to atherosclerosis in ApoE−/− mice

(2019) Qiuxia Liu et al.   MICROBIAL PATHOGENESIS

The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

(2018) Charlotte Bayer Christiansen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

On Burkholderiales order microorganisms and cystic fibrosis in Russia

(2018) Olga L. Voronina et al.   BMC GENOMICS

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

(2018) Shinobu Miyazaki-Anzai et al.   JOURNAL OF LIPID RESEARCH

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

(2018) Lesley Hoyles et al.   NATURE MEDICINE

Farnesoid X receptor agonist INT-767 attenuates liver steatosis and inflammation in rat model of nonalcoholic steatohepatitis

(2018) Ying-Bin Hu et al.   Drug Design Development and Therapy

Role of p38 MAPK in Atherosclerosis and Aortic Valve Sclerosis

(2018) Anna Reustle et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A dual agonist of farnesoid X receptor (FXR) and the G protein–coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice

(2017) Xiaoxin X. Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

(2017) Mariana X. Byndloss et al.   SCIENCE

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive MiceClinical Perspective

(2016) Francine Z. Marques et al.   CIRCULATION

Resveratrol Attenuates Trimethylamine- N -Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota

(2016) Ming-liang Chen et al.   mBio

Probiotics and Prebiotics: Present Status and Future Perspectives on Metabolic Disorders

(2016) Ji Yoo et al.   Nutrients

Targeted inhibition of STATs and IRFs as a potential treatment strategy in cardiovascular disease

(2016) Malgorzata Szelag et al.   Oncotarget

An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis

(2016) Jun Chen et al.   Genome Medicine

Bacterial Communities Associated with Atherosclerotic Plaques from Russian Individuals with Atherosclerosis

(2016) Elvira E. Ziganshina et al.   PLoS One

Microbiota of the Small Intestine Is Selectively Engulfed by Phagocytes of the Lamina Propria and Peyer’s Patches

(2016) Masatoshi Morikawa et al.   PLoS One

Histone deacetylases and atherosclerosis

(2015) Xia-xia Zheng et al.   ATHEROSCLEROSIS

Chemokines and their receptors in Atherosclerosis

(2015) Emiel P. C. van der Vorst et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Pro-inflammatory monocyte-macrophage polarization imbalance in human hypercholesterolemia and atherosclerosis

(2014) Gian Paolo Fadini et al.   ATHEROSCLEROSIS

γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L -Carnitine to TMAO

(2014) Robert A. Koeth et al.   Cell Metabolism

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice

(2014) Jingjing Wang et al.   ISME Journal

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

(2014) Xiang Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

The contributory role of gut microbiota in cardiovascular disease

(2014) W.H. Wilson Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure

(2014) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation

(2014) E.C. Aguilar et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota

(2014) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunity, atherosclerosis and cardiovascular disease

(2013) Johan Frostegård   BMC Medicine

Pathophysiology of Atherosclerosis Plaque Progression

(2013) Kenichi Sakakura et al.   Heart Lung and Circulation

Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion

(2013) Hariom Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Long-Term Stability of the Human Gut Microbiota

(2013) J. J. Faith et al.   SCIENCE

Structural Modifications of Bacterial Lipopolysaccharide that Facilitate Gram-Negative Bacteria Evasion of Host Innate Immunity

(2013) Motohiro Matsuura   Frontiers in Immunology

Angptl4 serves as an endogenous inhibitor of intestinal lipid digestion

(2013) Frits Mattijssen et al.   Molecular Metabolism

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Symptomatic atherosclerosis is associated with an altered gut metagenome

(2012) Fredrik H. Karlsson et al.   Nature Communications

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Human nutrition, the gut microbiome and the immune system

(2011) Andrew L. Kau et al.   NATURE

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Vaccination against atherosclerosis? Induction of atheroprotective immunity

(2009) Göran K. Hansson et al.   Seminars in Immunopathology

T-Cell Costimulation and Coinhibition in Atherosclerosis

(2008) Israel Gotsman et al.   CIRCULATION RESEARCH

MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets

(2008) Anthony J. Muslin   CLINICAL SCIENCE

Interferon gamma: A master regulator of atherosclerosis

(2008) James E. McLaren et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Imaging of atherosclerotic cardiovascular disease

(2008) Javier Sanz et al.   NATURE

Butyrate and trichostatin A attenuate nuclear factor κB activation and tumor necrosis factor α secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells

(2008) Makoto Usami et al.   NUTRITION RESEARCH