Modulation of Endotoxicity ofShigellaGeneralized Modules for Membrane Antigens (GMMA) by Genetic Lipid A Modifications

A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on Generalized Modules for Membrane Antigens (GMMA)

(2014) Oliver Koeberling et al.   VACCINE

Site-specific acylation changes in the lipid A of Escherichia coli lpxL mutants grown at high temperatures

(2013) Birgit Schilling et al.   Innate Immunity

Minor Modifications to the Phosphate Groups and the C3′ Acyl Chain Length of Lipid A in TwoBordetella pertussisStrains, BP338 and 18-323, Independently Affect Toll-like Receptor 4 Protein Activation

(2013) Nita R. Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

A scalable method for O-antigen purification applied to various Salmonella serovars

(2012) F. Micoli et al.   ANALYTICAL BIOCHEMISTRY

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

High Yield Production Process for Shigella Outer Membrane Particles

(2012) Francesco Berlanda Scorza et al.   PLoS One

Causative Species and Serotypes of Shigellosis in Mainland China: Systematic Review and Meta-Analysis

(2012) Zhili Chang et al.   PLoS One

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

(2012) U. Ohto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

(2011) A. Seubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phase 1 study of a meningococcal native outer membrane vesicle vaccine made from a group B strain with deleted lpxL1 and synX, over-expressed factor H binding protein, two PorAs and stabilized OpcA expression

(2011) P.B. Keiser et al.   VACCINE

Neisseria meningitidis lipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production

(2010) Tom Sprong et al.   Innate Immunity

Virulence and Immunomodulatory Roles of Bacterial Outer Membrane Vesicles

(2010) T. N. Ellis et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Evaluation of a Whole-Blood Cytokine Release Assay for Use in Measuring Endotoxin Activity of Group B Neisseria meningitidis Vaccines Made from Lipid A Acylation Mutants

(2009) M. B. Stoddard et al.   Clinical and Vaccine Immunology

Virulence, Inflammatory Potential, and Adaptive Immunity Induced by Shigella flexneri msbB Mutants

(2009) R. T. Ranallo et al.   INFECTION AND IMMUNITY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Meningococcal Outer Membrane Vesicle Vaccines Derived from Mutant Strains Engineered To Express Factor H Binding Proteins from Antigenic Variant Groups 1 and 2

(2008) O. Koeberling et al.   Clinical and Vaccine Immunology

Bactericidal Antibody Responses Elicited by a Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Factor H–Binding Protein and Genetically Attenuated Endotoxin

(2008) Oliver Koeberling et al.   JOURNAL OF INFECTIOUS DISEASES