An Intercellular Flow of Glutathione Regulated by Interleukin 6 Links Astrocytes and the Liver in the Pathophysiology of Amyotrophic Lateral Sclerosis

Glutathione in the Nervous System as a Potential Therapeutic Target to Control the Development and Progression of Amyotrophic Lateral Sclerosis

(2021) Kiyoung Kim   Antioxidants

NAD+ Precursors and Antioxidants for the Treatment of Amyotrophic Lateral Sclerosis

(2021) Elena Obrador et al.   Biomedicines

Lower and upper motor neuron involvement and their impact on disease prognosis in amyotrophic lateral sclerosis

(2021) MariaN Zakharova et al.   Neural Regeneration Research

Melanoma in the liver: Oxidative stress and the mechanisms of metastatic cell survival

(2020) Elena Obrador et al.   SEMINARS IN CANCER BIOLOGY

Oxidative Stress, Neuroinflammation and Mitochondria in the Pathophysiology of Amyotrophic Lateral Sclerosis

(2020) Elena Obrador et al.   Antioxidants

Genetics of amyotrophic lateral sclerosis: A review

(2019) Stéphane Mathis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

New insights on the disease contribution of neuroinflammation in amyotrophic lateral sclerosis

(2019) Aude Chiot et al.   CURRENT OPINION IN NEUROLOGY

Novel analogs of sulfasalazine as system x c − antiporter inhibitors: Insights from the molecular modeling studies

(2019) Dhavalkumar Patel et al.   DRUG DEVELOPMENT RESEARCH

IL6 receptor358Ala variant and trans-signaling are disease modifiers in amyotrophic lateral sclerosis

(2019) Marlena Wosiski-Kuhn et al.   Neurology-Neuroimmunology & Neuroinflammation

Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis

(2018) Mariana Pehar et al.   CURRENT PHARMACEUTICAL DESIGN

An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice

(2018) Nastasia K-H Lim et al.   Jove-Journal of Visualized Experiments

Methods for the detection of reactive oxygen species

(2018) Yinfeng Zhang et al.   Analytical Methods

Aberrant astrocytic expression of chondroitin sulfate proteoglycan receptors in a rat model of amyotrophic lateral sclerosis

(2017) Tomomi Shijo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Amyotrophic lateral sclerosis

(2017) Michael A van Es et al.   LANCET

Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism

(2016) María Benlloch et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of interleukin-6 signaling in nervous tissue

(2016) Michelle Rothaug et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A novel Na+-Independent alanine-serine-cysteine transporter 1 inhibitor inhibits both influx and efflux of D-Serine

(2016) Katsuya Sakimura et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis

(2016) Xinlei Yu et al.   Scientific Reports

High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord

(2015) Marie-Josée Beaudet et al.   Scientific Reports

Innate lymphotoxin receptor mediated signaling promotes HSV-1 associated neuroinflammation and viral replication

(2015) Yong Liang et al.   Scientific Reports

Glucocorticoid Receptor Knockdown Decreases the Antioxidant Protection of B16 Melanoma Cells: An Endocrine System-Related Mechanism that Compromises Metastatic Cell Resistance to Vascular Endothelium-Induced Tumor Cytotoxicity

(2014) Elena Obrador et al.   PLoS One

Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors

(2013) Stephanie Wickham et al.   BIOCHEMICAL JOURNAL

Role of IL-6 in Mycobacterium avium-Associated Immune Reconstitution Inflammatory Syndrome

(2013) D. L. Barber et al.   JOURNAL OF IMMUNOLOGY

Astrocytes: The Missing Link in Neurologic Disease?

(2013) Chia-Ching John Lin et al.   Seminars in Pediatric Neurology

Interleukin-6, a Major Cytokine in the Central Nervous System

(2012) María Erta et al.   International Journal of Biological Sciences

Interleukin-6 signalling: More than Jaks and STATs

(2011) René Eulenfeld et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Intertissue Flow of Glutathione (GSH) as a Tumor Growth-promoting Mechanism

(2011) Elena Obrador et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astrogliosis in amyotrophic lateral sclerosis: Role and therapeutic potential of astrocytes

(2010) Marcelo R. Vargas et al.   Neurotherapeutics

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology

(2008) Nazzareno Ballatori et al.   MOLECULAR ASPECTS OF MEDICINE