Engineered Human Meniscus in Modeling Sex Differences of Knee Osteoarthritis in Vitro

Suppression of Hypertrophy During in vitro Chondrogenesis of Cocultures of Human Mesenchymal Stem Cells and Nasal Chondrocytes Correlates With Lack of in vivo Calcification and Vascular Invasion

(2021) Matthew Anderson-Baron et al.   Frontiers in Bioengineering and Biotechnology

Comparison of joint degeneration and pain in male and female mice in DMM model of osteoarthritis

(2021) H.S. Hwang et al.   OSTEOARTHRITIS AND CARTILAGE

A dysfunctional TRPV4–GSK3β pathway prevents osteoarthritic chondrocytes from sensing changes in extracellular matrix viscoelasticity

(2021) Pranay Agarwal et al.   Nature Biomedical Engineering

Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis

(2021) Whasil Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechano-Hypoxia Conditioning of Engineered Human Meniscus

(2021) Alexander R. A. Szojka et al.   Frontiers in Bioengineering and Biotechnology

Mechanotransduction in meniscus fibrochondrocytes: What about caveolae?

(2021) Margaret J. Vyhlidal et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Enhanced chondrogenic phenotype of primary bovine articular chondrocytes in Fibrin-Hyaluronan hydrogel by multi-axial mechanical loading and FGF18

(2020) Bernardo P. Antunes et al.   Acta Biomaterialia

Mechanotransduction pathways in the regulation of cartilage chondrocyte homoeostasis

(2020) Zhenxing Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Sex differences in proximal femur shape: findings from a population-based study in adolescents

(2020) Monika Frysz et al.   Scientific Reports

Tissue Engineering of Cartilage Using a Random Positioning Machine

(2020) Markus Wehland et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Articular cartilage and sternal fibrocartilage respond differently to extended microgravity

(2019) Jamie Fitzgerald et al.   NPJ Microgravity

CITED2 mediates the cross‐talk between mechanical loading and IL‐4 to promote chondroprotection

(2019) Zhiyong He et al.   Annals of the New York Academy of Sciences

Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1

(2019) Takashi Ohtsuki et al.   EXPERIMENTAL CELL RESEARCH

Influence of Mechanical Unloading on Articular Chondrocyte Dedifferentiation

(2018) Simon Wuest et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Differences in neuroimmune signalling between male and female patients suffering from knee osteoarthritis

(2018) E. Kosek et al.   JOURNAL OF NEUROIMMUNOLOGY

Sex-specific walking kinematics and kinetics in individuals with unilateral, symptomatic hip osteoarthritis: A cross sectional study

(2018) Kim Allison et al.   GAIT & POSTURE

Models of osteoarthritis: the good, the bad and the promising

(2018) P.J. Cope et al.   OSTEOARTHRITIS AND CARTILAGE

MRTF-A signaling regulates the acquisition of the contractile phenotype in dedifferentiated chondrocytes

(2017) Justin Parreno et al.   MATRIX BIOLOGY

Mechanical loading regulates organization of the actin cytoskeleton and column formation in postnatal growth plate

(2017) Christy H. Killion et al.   MOLECULAR BIOLOGY OF THE CELL

Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes

(2017) M Rocio Servin-Vences et al.   eLife

Comparison of Simulated Microgravity and Hydrostatic Pressure for Chondrogenesis of hASC

(2017) Liliana F. Mellor et al.   Aerospace Medicine and Human Performance

Coculture of meniscus cells and mesenchymal stem cells in simulated microgravity

(2017) William M. Weiss et al.   NPJ Microgravity

Plasticity of Human Meniscus Fibrochondrocytes: A Study on Effects of Mitotic Divisions and Oxygen Tension

(2017) Yan Liang et al.   Scientific Reports

Gender differences in gait kinematics for patients with knee osteoarthritis

(2016) Angkoon Phinyomark et al.   BMC MUSCULOSKELETAL DISORDERS

Sex differences in knee joint loading: Cross-sectional study in geriatric population

(2016) Du Hyun Ro et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The OARSI standardised definition of osteoarthritis: A lay version

(2016) S. Blackburn et al.   OSTEOARTHRITIS AND CARTILAGE

The association of distal femur and proximal tibia shape with sex: The Osteoarthritis Initiative

(2016) Barton L. Wise et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Association of Body Composition and Hormonal and Inflammatory Factors With Tibial Cartilage Volume and Sex Difference in Cartilage Volume in Young Adults

(2016) Benny Antony et al.   ARTHRITIS CARE & RESEARCH

Characterization of osteoarthritic human knees indicates potential sex differences

(2016) Qingfen Pan et al.   Biology of Sex Differences

The effect of simulated microgravity on lumbar spine biomechanics: an in vitro study

(2015) Cory J. Laws et al.   EUROPEAN SPINE JOURNAL

Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9

(2015) Ganna Aleshcheva et al.   FASEB JOURNAL

Dynamic hydrostatic pressure enhances differentially the chondrogenesis of meniscal cells from the inner and outer zone

(2015) J. Zellner et al.   JOURNAL OF BIOMECHANICS

Mechanobiology of the meniscus

(2015) Amy L. McNulty et al.   JOURNAL OF BIOMECHANICS

Optimal 3D Culture of Primary Articular Chondrocytes for Use in the Rotating Wall Vessel Bioreactor

(2014) Liliana F. Mellor et al.   AVIATION SPACE AND ENVIRONMENTAL MEDICINE

Acute cell viability and nitric oxide release in lateral menisci following closed-joint knee injury in a lapine model of post-traumatic osteoarthritis

(2014) Megan L Killian et al.   BMC MUSCULOSKELETAL DISORDERS

Simulated microgravity affects chondrogenesis and hypertrophy of human mesenchymal stem cells

(2014) Susanne Mayer-Wagner et al.   INTERNATIONAL ORTHOPAEDICS

Women with Osteoarthritis have Elevated Synovial Fluid Levels of Insulin-Like Growth Factor (IGF)-1 and IGF-Binding Protein-3

(2014) Shirin Hooshmand et al.   JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY

Comparative Study of Sex Differences in Distal Femur Morphology in Osteoarthritic Knees in a Chinese Population

(2014) Bo Yang et al.   PLoS One

The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes

(2014) Yue Gao et al.   Biomed Research International

Estrogen Aggravates Iodoacetate-induced Temporomandibular Joint Osteoarthritis

(2013) X.D. Wang et al.   JOURNAL OF DENTAL RESEARCH

The effects of simulated microgravity on intervertebral disc degeneration

(2013) Li Jin et al.   Spine Journal

Hormonal modulation of connective tissue homeostasis and sex differences in risk for osteoarthritis of the knee

(2013) Barbara D Boyan et al.   Biology of Sex Differences

Addressing the gaps: sex differences in osteoarthritis of the knee

(2013) Barbara D Boyan et al.   Biology of Sex Differences

Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

(2012) J. C. H. Leijten et al.   ARTHRITIS AND RHEUMATISM

Ground-Based Facilities for Simulation of Microgravity: Organism-Specific Recommendations for Their Use, and Recommended Terminology

(2012) Raul Herranz et al.   ASTROBIOLOGY

Effects of Unloading on Knee Articular Cartilage T1rho and T2 Magnetic Resonance Imaging Relaxation Times: A Case Series

(2012) Richard B. Souza et al.   JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY

Sex Differences in Osteoarthritis of the Knee

(2012) B. D. Boyan et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Christopher J L Murray et al.   LANCET

The Effect of the Duration of Mechanical Stimulation and Post-Stimulation Culture on the Structure and Properties of Dynamically Compressed Tissue-Engineered Menisci

(2012) Jennifer L. Puetzer et al.   TISSUE ENGINEERING PART A

Mechanical contributors to sex differences in idiopathic knee osteoarthritis

(2012) Daniel P Nicolella et al.   Biology of Sex Differences

Simulated microgravity using a rotary cell culture system promotes chondrogenesis of human adipose-derived mesenchymal stem cells via the p38 MAPK pathway

(2011) Bo Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interleukin-1, tumor necrosis factor-alpha, and transforming growth factor-beta 1 and integrative meniscal repair: influences on meniscal cell proliferation and migration

(2011) Katherine M Riera et al.   ARTHRITIS RESEARCH & THERAPY

Women lose patella cartilage at a faster rate than men: A 4.5-year cohort study of subjects with knee OA

(2010) Sharon L. Brennan et al.   MATURITAS

Dynamic loading enhances integrative meniscal repair in the presence of interleukin-1

(2010) A.L. McNulty et al.   OSTEOARTHRITIS AND CARTILAGE

Neocartilage Formation in 1 g, Simulated, and Microgravity Environments: Implications for Tissue Engineering

(2010) Vlada Stamenković et al.   TISSUE ENGINEERING PART A

Ultrasound Evaluation of Site-Specific Effect of Simulated Microgravity on Articular Cartilage

(2010) Qing Wang et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Calcium deposition in osteoarthritic meniscus and meniscal cell culture

(2010) Yubo Sun et al.   ARTHRITIS RESEARCH & THERAPY

Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders

(2010) Rita Dreier   ARTHRITIS RESEARCH & THERAPY

Hydrostatic Pressure in Articular Cartilage Tissue Engineering: From Chondrocytes to Tissue Regeneration

(2009) Benjamin D. Elder et al.   TISSUE ENGINEERING PART B-REVIEWS

Effects of TGF-β1 and hydrostatic pressure on meniscus cell-seeded scaffolds

(2008) Najmuddin J. Gunja et al.   BIOMATERIALS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols