Mechano-Hypoxia Conditioning of Engineered Human Meniscus

Engineered human meniscus’ matrix-forming phenotype is unaffected by low strain dynamic compression under hypoxic conditions

(2021) Alexander R. A. Szojka et al.   PLoS One

Time course of 3D fibrocartilage formation by expanded human meniscus fibrochondrocytes in hypoxia

(2021) Alexander R. A. Szojka et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bone Marrow Mesenchymal Stem Cells-Derived Tissues are Mechanically Superior to Meniscus Cells'

(2020) Hoda Elkhenany et al.   TISSUE ENGINEERING PART A

Driving Hierarchical Collagen Fiber Formation for Functional Tendon, Ligament, and Meniscus Replacement

(2020) Jennifer L. Puetzer et al.   BIOMATERIALS

A Guide for Using Mechanical Stimulation to Enhance Tissue-Engineered Articular Cartilage Properties

(2018) Evelia Y. Salinas et al.   TISSUE ENGINEERING PART B-REVIEWS

Engineering large cartilage tissues using dynamic bioreactor culture at defined oxygen conditions

(2018) Andrew C Daly et al.   Journal of Tissue Engineering

Hypoxia and TGF-β3 Synergistically Mediate Inner Meniscus-Like Matrix Formation by Fibrochondrocytes

(2018) Alexander R.A. Szojka et al.   TISSUE ENGINEERING PART A

Global chondrocyte gene expression after a single anabolic loading period: Time evolution and re-inducibility of mechano-responses

(2017) Simone Scholtes et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Plasticity of Human Meniscus Fibrochondrocytes: A Study on Effects of Mitotic Divisions and Oxygen Tension

(2017) Yan Liang et al.   Scientific Reports

Physiologically Distributed Loading Patterns Drive the Formation of Zonally Organized Collagen Structures in Tissue-Engineered Meniscus

(2016) Jennifer L. Puetzer et al.   TISSUE ENGINEERING PART A

Optimal Seeding Densities forIn VitroChondrogenesis of Two- and Three-Dimensional-Isolated and -Expanded Bone Marrow-Derived Mesenchymal Stromal Stem Cells Within a Porous Collagen Scaffold

(2016) Troy D. Bornes et al.   TISSUE ENGINEERING PART C-METHODS

Swelling significantly affects the material properties of the menisci in compression

(2015) Stephen H.J. Andrews et al.   JOURNAL OF BIOMECHANICS

Dynamic hydrostatic pressure enhances differentially the chondrogenesis of meniscal cells from the inner and outer zone

(2015) J. Zellner et al.   JOURNAL OF BIOMECHANICS

Mechanobiology of the meniscus

(2015) Amy L. McNulty et al.   JOURNAL OF BIOMECHANICS

Biomechanics and mechanobiology in functional tissue engineering

(2014) Farshid Guilak et al.   JOURNAL OF BIOMECHANICS

Medial meniscal displacement and strain in three dimensions under compressive loads: MR assessment

(2013) Maren Freutel et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Low oxygen tension increased fibronectin fragment induced catabolic activities - response prevented with biomechanical signals

(2013) Eleanor Parker et al.   ARTHRITIS RESEARCH & THERAPY

Mechanical stretch increases Smad3-dependent CCN2 expression in inner meniscus cells

(2012) Takayuki Furumatsu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Oxygen Tension Is a Determinant of the Matrix-Forming Phenotype of Cultured Human Meniscal Fibrochondrocytes

(2012) Adetola B. Adesida et al.   PLoS One

The Effect of the Duration of Mechanical Stimulation and Post-Stimulation Culture on the Structure and Properties of Dynamically Compressed Tissue-Engineered Menisci

(2012) Jennifer L. Puetzer et al.   TISSUE ENGINEERING PART A

Effects of biomimetic surfaces and oxygen tension on redifferentiation of passaged human fibrochondrocytes in 2D and 3D cultures

(2011) Guak-Kim Tan et al.   BIOMATERIALS

The knee meniscus: Structure–function, pathophysiology, current repair techniques, and prospects for regeneration

(2011) Eleftherios A. Makris et al.   BIOMATERIALS

Mechanical stretch enhances COL2A1 expression on chromatin by inducing SOX9 nuclear translocalization in inner meniscus cells

(2011) Tomoko Kanazawa et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Tension-Compression Loading with Chemical Stimulation Results in Additive Increases to Functional Properties of Anatomic Meniscal Constructs

(2011) Daniel J. Huey et al.   PLoS One

The Basic Science of Human Knee Menisci

(2011) Alice J. S. Fox et al.   Sports Health-A Multidisciplinary Approach

Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression

(2010) Eric G. Meyer et al.   JOURNAL OF BIOMECHANICS

Dynamic compressive loading of image-guided tissue engineered meniscal constructs

(2010) Jeffrey J. Ballyns et al.   JOURNAL OF BIOMECHANICS

The Knee Meniscus: A Complex Tissue of Diverse Cells

(2009) Johannah Sanchez-Adams et al.   Cellular and Molecular Bioengineering

Effects of hydrostatic pressure on leporine meniscus cell-seeded PLLA scaffolds

(2009) Najmuddin J. Gunja et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effects of TGF-β1 and hydrostatic pressure on meniscus cell-seeded scaffolds

(2008) Najmuddin J. Gunja et al.   BIOMATERIALS

Development and validation of a novel bioreactor system for load- and perfusion-controlled tissue engineering of chondrocyte-constructs

(2008) Ronny M. Schulz et al.   BIOTECHNOLOGY AND BIOENGINEERING