Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

The Rotterdam Study: 2012 objectives and design update

(2011) Albert Hofman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Dual function of β-catenin in articular cartilage growth and degeneration at different stages of postnatal cartilage development

(2011) Bo Ning et al.   INTERNATIONAL ORTHOPAEDICS

WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways

(2011) Giovanna Nalesso et al.   JOURNAL OF CELL BIOLOGY

Inhibition of Gsk3β in cartilage induces osteoarthritic features through activation of the canonical Wnt signaling pathway

(2011) R.L. Miclea et al.   OSTEOARTHRITIS AND CARTILAGE

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Large-scale analysis of association betweenGDF5andFRZBvariants and osteoarthritis of the hip, knee, and hand

(2009) Evangelos Evangelou et al.   ARTHRITIS AND RHEUMATISM

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE

Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy

(2008) C J Brew et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of β‐catenin signaling in articular chondrocytes results in articular cartilage destruction

(2008) Mei Zhu et al.   ARTHRITIS AND RHEUMATISM

New insights into osteoarthritis: early developmental features of an ageing-related disease

(2008) Steffan Daniël Bos et al.   CURRENT OPINION IN RHEUMATOLOGY

Regulation of Osteoarthritis Development by Wnt–β-catenin Signaling Through the Endochondral Ossification Process

(2008) Hiroshi Kawaguchi   JOURNAL OF BONE AND MINERAL RESEARCH

Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

(2008) Mei Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Endochondral bone tissue engineering using embryonic stem cells

(2008) J. M. Jukes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA