Epithelial-Mesenchymal Transition Induces GSDME Transcriptional Activation for Inflammatory Pyroptosis
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Epithelial-Mesenchymal Transition Induces GSDME Transcriptional Activation for Inflammatory Pyroptosis
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-12-01
DOI
10.3389/fcell.2021.781365
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Fueling the Fire: Inflammatory Forms of Cell Death and Implications for Cancer Immunotherapy
- (2021) Sheera R. Rosenbaum et al. Cancer Discovery
- Lighting a Fire: Can We Harness Pyroptosis to Ignite Antitumor Immunity?
- (2021) Zhibin Zhang et al. Cancer Immunology Research
- Gasdermin E–mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome
- (2020) Yuying Liu et al. Science Immunology
- Gasdermin E suppresses tumour growth by activating anti-tumour immunity
- (2020) Zhibin Zhang et al. NATURE
- A bioorthogonal system reveals antitumour immune function of pyroptosis
- (2020) Qinyang Wang et al. NATURE
- Cell Death in the Origin and Treatment of Cancer
- (2020) Andreas Strasser et al. MOLECULAR CELL
- PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
- (2020) Junwei Hou et al. NATURE CELL BIOLOGY
- Emerging connectivity of programmed cell death pathways and its physiological implications
- (2020) Sammy Bedoui et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- GSDME and its role in cancer: From behind the scenes to the front of the stage
- (2020) Elke De Schutter et al. INTERNATIONAL JOURNAL OF CANCER
- A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma
- (2019) Mengjiao Wu et al. EBioMedicine
- Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro
- (2019) Pian Yu et al. ACTA PHARMACOLOGICA SINICA
- Genome-wide DNA methylation analysis revealed stable DNA methylation status during decidualization in human endometrial stromal cells
- (2019) Ryo Maekawa et al. BMC GENOMICS
- Next-generation characterization of the Cancer Cell Line Encyclopedia
- (2019) Mahmoud Ghandi et al. NATURE
- IRF2 transcriptionally induces GSDMD expression for pyroptosis
- (2019) Nobuhiko Kayagaki et al. Science Signaling
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
- (2019) Corey Rogers et al. Nature Communications
- Cellular Plasticity in Cancer
- (2019) Salina Yuan et al. Cancer Discovery
- Cell death–mediated cytokine release and its therapeutic implications
- (2019) David E. Place et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Epigenetics-Based Tumor Cells Pyroptosis for Enhancing the Immunological Effect of Chemotherapeutic Nanocarriers
- (2019) Jin-Xuan Fan et al. NANO LETTERS
- The Gasdermin E gene Potential as a Pan-Cancer Biomarker, While Discriminating between Different Tumor Types
- (2019) Joe Ibrahim et al. Cancers
- Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis
- (2019) Dan A. Erkes et al. Cancer Discovery
- An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
- (2018) Jianfang Liu et al. CELL
- Oncogenic Signaling Pathways in The Cancer Genome Atlas
- (2018) Francisco Sanchez-Vega et al. CELL
- Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
- (2018) Katherine A. Hoadley et al. CELL
- Identification of the tumour transition states occurring during EMT
- (2018) Ievgenia Pastushenko et al. NATURE
- Clinicopathological, microenvironmental and genetic determinants of molecular subtypes in KEAP1/NRF2-mutant lung cancer
- (2018) Mei-Chun Cai et al. INTERNATIONAL JOURNAL OF CANCER
- Non-redundant functions of EMT transcription factors
- (2018) Marc P. Stemmler et al. NATURE CELL BIOLOGY
- New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
- (2018) Anushka Dongre et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
- (2017) Yupeng Wang et al. NATURE
- Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
- (2017) Matthew J. Hangauer et al. NATURE
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
- Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
- (2017) Corey Rogers et al. Nature Communications
- Pore-forming activity and structural autoinhibition of the gasdermin family
- (2016) Jingjin Ding et al. NATURE
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer
- (2016) J. F. Gainor et al. Cancer Discovery
- Tumor Budding: The Name is EMT. Partial EMT.
- (2016) Alexandru Grigore et al. Journal of Clinical Medicine
- Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
- (2015) Wan-ting He et al. CELL RESEARCH
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Zeb2: A multifunctional regulator of nervous system development
- (2015) Shane V. Hegarty et al. PROGRESS IN NEUROBIOLOGY
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- The expression and regulation of DFNA5 in human hepatocellular carcinoma DFNA5 in hepatocellular carcinoma
- (2013) Cong-Jun Wang et al. MOLECULAR BIOLOGY REPORTS
- Multilayer control of the EMT master regulators
- (2013) H Zheng et al. ONCOGENE
- Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
- (2012) Zhenfeng Zhang et al. NATURE GENETICS
- Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
- (2011) L. V. Sequist et al. Science Translational Medicine
- Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
- (2010) Pan Du et al. BMC BIOINFORMATICS
- Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
- (2009) Piyush B. Gupta et al. CELL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer
- (2008) Myoung Sook Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma
- (2008) M S Kim et al. ONCOGENE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More