A Different Facet of p53 Function: Regulation of Immunity and Inflammation During Tumor Development
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Title
A Different Facet of p53 Function: Regulation of Immunity and Inflammation During Tumor Development
Authors
Keywords
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Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-10-20
DOI
10.3389/fcell.2021.762651
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Note: Only part of the references are listed.- Mutant p53 suppresses innate immune signaling to promote tumorigenesis
- (2021) Monisankar Ghosh et al. CANCER CELL
- The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity
- (2021) Jiajia Zhou et al. NATURE IMMUNOLOGY
- p53, cancer and the immune response
- (2020) Julianna Blagih et al. JOURNAL OF CELL SCIENCE
- Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses
- (2020) Julianna Blagih et al. Cell Reports
- cGAS in action: Expanding roles in immunity and inflammation
- (2019) Andrea Ablasser et al. SCIENCE
- Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers
- (2019) Parisa Malekzadeh et al. JOURNAL OF CLINICAL INVESTIGATION
- IFN-gamma-induced PD-L1 expression in melanoma depends on p53 expression
- (2019) Alexander Thiem et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Control of metabolism by p53 – Cancer and beyond
- (2018) Christiaan F. Labuschagne et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- T-cell responses toTP53"hotspot" mutations and unique neoantigens expressed by human ovarian cancers
- (2018) Drew C Deniger et al. CLINICAL CANCER RESEARCH
- TP53,STK11andEGFRMutations Predict Tumor Immune Profile and the Response to anti-PD-1 in Lung Adenocarcinoma
- (2018) Jerome Biton et al. CLINICAL CANCER RESEARCH
- Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features
- (2018) Sharathchandra Arandkar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The hypoxic tumour microenvironment
- (2018) Varvara Petrova et al. Oncogenesis
- Role of p53 in the Regulation of the Inflammatory Tumor Microenvironment and Tumor Suppression
- (2018) Ikuno Uehara et al. Cancers
- p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression
- (2018) Ivano Amelio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling
- (2017) Homa Rahnamoun et al. Nature Communications
- Coinhibitory Pathways in Immunotherapy for Cancer
- (2016) Susanne H. Baumeister et al. Annual Review of Immunology
- Lack of p53 Augments Antitumor Functions in Cytolytic T Cells
- (2016) Anirban Banerjee et al. CANCER RESEARCH
- Loss of P53 Function Activates JAK2–STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival
- (2016) Sonja M. Wörmann et al. GASTROENTEROLOGY
- Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability
- (2016) Bernhard Mlecnik et al. IMMUNITY
- Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
- (2016) Christina Pfirschke et al. IMMUNITY
- Clinicopathological and prognostic significance of programmed cell death ligand-1 expression in lung adenocarcinoma and its relationship with p53 status
- (2016) Yoon Jin Cha et al. LUNG CANCER
- Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
- (2016) E. Stronen et al. SCIENCE
- The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis
- (2016) Bernhard Mlecnik et al. Science Translational Medicine
- p53 and the Carcinogenicity of Chronic Inflammation
- (2016) Andrei V. Gudkov et al. Cold Spring Harbor Perspectives in Medicine
- Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
- (2015) Padmanee Sharma et al. CELL
- PDL1 Regulation by p53 via miR-34
- (2015) Maria Angelica Cortez et al. JNCI-Journal of the National Cancer Institute
- Phagocytosis of apoptotic cells in homeostasis
- (2015) Sanja Arandjelovic et al. NATURE IMMUNOLOGY
- TLR4 has a TP53-dependent dual role in regulating breast cancer cell growth
- (2015) Svasti Haricharan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A p53-regulated immune checkpoint relevant to cancer
- (2015) L. Zitvogel et al. SCIENCE
- Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53
- (2015) K. W. Yoon et al. SCIENCE
- The predictive value of centre tumour CD8+ T cells in patients with hepatocellular carcinoma: comparison with Immunoscore
- (2015) Cheng Sun et al. Oncotarget
- p53 in the Myeloid Lineage Modulates an Inflammatory Microenvironment Limiting Initiation and Invasion of Intestinal Tumors
- (2015) Xue-Yan He et al. Cell Reports
- PDL1 Regulation by p53 via miR-34
- (2015) Maria Angelica Cortez et al. JNCI-Journal of the National Cancer Institute
- Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators
- (2015) Isabelle Le Mercier et al. Frontiers in Immunology
- New perspective on targeting the tumor suppressor p53 pathway in the tumor microenvironment to enhance the efficacy of immunotherapy
- (2015) Gang Guo et al. Journal for ImmunoTherapy of Cancer
- Prognostic Role of Serum Antibody Immunity to p53 Oncogenic Protein in Ovarian Cancer: A Systematic Review and a Meta-Analysis
- (2015) Marica Garziera et al. PLoS One
- Mutant p53 in Cancer: New Functions and Therapeutic Opportunities
- (2014) Patricia A.J. Muller et al. CANCER CELL
- p53 and NF-κB Coregulate Proinflammatory Gene Responses in Human Macrophages
- (2014) Julie M. Lowe et al. CANCER RESEARCH
- Caught in the cross fire: p53 in inflammation
- (2014) Tomer Cooks et al. CARCINOGENESIS
- Downmodulation of Tumor Suppressor p53 by T Cell Receptor Signaling Is Critical for Antigen-Specific CD4+ T Cell Responses
- (2014) Masashi Watanabe et al. IMMUNITY
- Fibroblast heterogeneity in the cancer wound
- (2014) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mutant p53 Reprograms TNF Signaling in Cancer Cells through Interaction with the Tumor Suppressor DAB2IP
- (2014) Giulio Di Minin et al. MOLECULAR CELL
- Drugging the p53 pathway: understanding the route to clinical efficacy
- (2014) Kian Hoe Khoo et al. NATURE REVIEWS DRUG DISCOVERY
- Peptides genetically selected for NF- B activation cooperate with oncogene Ras and model carcinogenic role of inflammation
- (2014) V. Natarajan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adaptive Resistance to Immunotherapy Directed Against p53 Can be Overcome by Global Expression of Tumor-Antigens in Dendritic Cells
- (2014) Matjaz Humar et al. Frontiers in Oncology
- Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer
- (2013) Tomer Cooks et al. CANCER CELL
- Trp53 Inactivation in the Tumor Microenvironment Promotes Tumor Progression by Expanding the Immunosuppressive Lymphoid-like Stromal Network
- (2013) G. Guo et al. CANCER RESEARCH
- Non-Cell-Autonomous Tumor Suppression by p53
- (2013) Amaia Lujambio et al. CELL
- From the immune contexture to the Immunoscore: the role of prognostic and predictive immune markers in cancer
- (2013) Helen Angell et al. CURRENT OPINION IN IMMUNOLOGY
- p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
- (2013) Albert R. Davalos et al. JOURNAL OF CELL BIOLOGY
- Tumor Suppressor p53 Inhibits Systemic Autoimmune Diseases by Inducing Regulatory T Cells
- (2013) H. Kawashima et al. JOURNAL OF IMMUNOLOGY
- Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence
- (2013) Peng Jiang et al. NATURE
- Inhibitory Effect of Tumor Suppressor p53 on Proinflammatory Chemokine Expression in Ovarian Cancer Cells by Reducing Proteasomal Degradation of IκB
- (2013) Deok-Soo Son et al. PLoS One
- p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1
- (2013) Bei Wang et al. Nature Communications
- Cancer and Inflammation: An Old Intuition with Rapidly Evolving New Concepts
- (2012) Giorgio Trinchieri Annual Review of Immunology
- Immunogenic Cell Death in Cancer Therapy
- (2012) Guido Kroemer et al. Annual Review of Immunology
- p53 Controls Autoimmune Arthritis via STAT-Mediated Regulation of the Th17 Cell/Treg Cell Balance in Mice
- (2012) Jin-Sil Park et al. ARTHRITIS AND RHEUMATISM
- Loss of p53 in Enterocytes Generates an Inflammatory Microenvironment Enabling Invasion and Lymph Node Metastasis of Carcinogen-Induced Colorectal Tumors
- (2012) Sarah Schwitalla et al. CANCER CELL
- Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy
- (2012) M. A. Swartz et al. CANCER RESEARCH
- Cellular Constituents of Immune Escape within the Tumor Microenvironment
- (2012) S. P. Kerkar et al. CANCER RESEARCH
- The MDM2 inhibitor Nutlin-3 modulates dendritic cell–induced T cell proliferation
- (2012) Chiara Gasparini et al. HUMAN IMMUNOLOGY
- Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression
- (2012) Suzanne Ostrand-Rosenberg et al. SEMINARS IN CANCER BIOLOGY
- Human NK Cells Are Alerted to Induction of p53 in Cancer Cells by Upregulation of the NKG2D Ligands ULBP1 and ULBP2
- (2011) S. Textor et al. CANCER RESEARCH
- Tumor Suppressive MicroRNAs miR-34a/c Control Cancer Cell Expression of ULBP2, a Stress-Induced Ligand of the Natural Killer Cell Receptor NKG2D
- (2011) A. Heinemann et al. CANCER RESEARCH
- Programmed Cell Death in Animal Development and Disease
- (2011) Yaron Fuchs et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
- (2011) T. R. Cox et al. Disease Models & Mechanisms
- Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis
- (2011) Shuzhong Zhang et al. FASEB JOURNAL
- Four faces of cellular senescence
- (2011) Francis Rodier et al. JOURNAL OF CELL BIOLOGY
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- The Toll-Like Receptor Gene Family Is Integrated into Human DNA Damage and p53 Networks
- (2011) Daniel Menendez et al. PLoS Genetics
- A role for p53 in the regulation of extracellular matrix metalloproteinase inducer in human cancer cells
- (2010) Hua Zhu et al. CANCER BIOLOGY & THERAPY
- p53 Status in Stromal Fibroblasts Modulates Tumor Growth in an SDF1-Dependent Manner
- (2010) Y. Addadi et al. CANCER RESEARCH
- Autoimmunity and the Clearance of Dead Cells
- (2010) Shigekazu Nagata et al. CELL
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism
- (2010) Prashanth Ak et al. FASEB JOURNAL
- Clearance of apoptotic cells: implications in health and disease
- (2010) Michael R. Elliott et al. JOURNAL OF CELL BIOLOGY
- Type I interferon: friend or foe?
- (2010) Giorgio Trinchieri JOURNAL OF EXPERIMENTAL MEDICINE
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Translating p53 into the clinic
- (2010) Chit Fang Cheok et al. Nature Reviews Clinical Oncology
- Cross talk between stimulated NF-κB and the tumor suppressor p53
- (2010) G Schneider et al. ONCOGENE
- IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
- (2009) Sergei Grivennikov et al. CANCER CELL
- Involvement of stromal p53 in tumor-stroma interactions
- (2009) Jair Bar et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Activated p53 induces NF-κB DNA binding but suppresses its transcriptional activation
- (2008) Keiko Kawauchi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines
- (2008) M. Taura et al. MOLECULAR AND CELLULAR BIOLOGY
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
- p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation
- (2008) Keiko Kawauchi et al. NATURE CELL BIOLOGY
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