Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia

Tumor heterogeneity in autophagy-dependent ferroptosis

(2021) Jingbo Li et al.   Autophagy

Cellular degradation systems in ferroptosis

(2021) Xin Chen et al.   CELL DEATH AND DIFFERENTIATION

Recent insight into the role of FBXW7 as a tumor suppressor

(2020) Kanae Yumimoto et al.   SEMINARS IN CANCER BIOLOGY

Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma

(2020) Yongfei Yang et al.   Nature Communications

Acute lymphoblastic leukaemia

(2020) Florent Malard et al.   LANCET

FBXW7 in Cancer: What Has Been Unraveled Thus Far?

(2019) Bethsebie Lalduhsaki Sailo et al.   Cancers

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

(2019) Ningning Li et al.   Oncogenesis

Ferroptosis is a type of autophagy-dependent cell death

(2019) Borong Zhou et al.   SEMINARS IN CANCER BIOLOGY

Targeting Ferroptosis to Iron Out Cancer

(2019) Behrouz Hassannia et al.   CANCER CELL

RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells

(2019) Zili Zhang et al.   Autophagy

Cellular quality control by the ubiquitin-proteasome system and autophagy

(2019) Christian Pohl et al.   SCIENCE

Erastin/sorafenib induces cisplatin‑resistant non‑small cell lung cancer cell ferroptosis through inhibition of the Nrf2/xCT pathway

(2019) Yu Li et al.   Oncology Letters

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FBXW7 suppresses epithelial-mesenchymal transition and chemo-resistance of non-small-cell lung cancer cells by targeting snai1 for ubiquitin-dependent degradation

(2018) Guodong Xiao et al.   CELL PROLIFERATION

FBXW7: a critical tumor suppressor of human cancers

(2018) Chien-Hung Yeh et al.   Molecular Cancer

SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis

(2018) Li-Yu Huang et al.   Nature Communications

VDAC2 enables BAX to mediate apoptosis and limit tumor development

(2018) Hui San Chin et al.   Nature Communications

Creation of a human T-ALL cell line online database

(2017) Barbara Squiban et al.   LEUKEMIA & LYMPHOMA

An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network

(2017) Yang Li et al.   Nature Communications

The molecular mechanisms of chemoresistance in cancers

(2017) Hua-Chuan Zheng   Oncotarget

VDAC2-specific cellular functions and the underlying structure

(2016) Shamim Naghdi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy, a key mechanism of oncogenesis and resistance in leukemia

(2016) Patrick Auberger et al.   BLOOD

Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer

(2016) Jong-Lyel Roh et al.   CANCER LETTERS

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

(2016) S Ma et al.   Cell Death & Disease

VDAC3 As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology

(2016) Simona Reina et al.   Frontiers in Oncology

Emerging roles for the FBXW7 ubiquitin ligase in leukemia and beyond

(2015) Nikos Kourtis et al.   CURRENT OPINION IN CELL BIOLOGY

Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique

(2014) Angela Messina et al.   Molecular BioSystems

The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability

(2013) Bryan King et al.   CELL

Investigation of the atypicalFBXW7mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

(2013) Hayley Davis et al.   GUT

Autophagy in blood cancers: biological role and therapeutic implications

(2013) A. Nencioni et al.   HAEMATOLOGICA

Voltage-dependent Anion Channels Modulate Mitochondrial Metabolism in Cancer Cells

(2013) Eduardo N. Maldonado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute lymphoblastic leukaemia

(2013) Hiroto Inaba et al.   LANCET

Relapsed childhood acute lymphoblastic leukaemia

(2013) Deepa Bhojwani et al.   LANCET ONCOLOGY

Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia

(2012) S. L. Maude et al.   BLOOD

Apoptosis Deregulation Influences Chemoresistance to Azaguanine in Human Leukemic Cell Lines

(2012) A. B. Sarmento-Ribeiro et al.   CANCER INVESTIGATION

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

High Accuracy Mutation Detection in Leukemia on a Selected Panel of Cancer Genes

(2012) Zeynep Kalender Atak et al.   PLoS One

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

(2011) Ingrid E. Wertz et al.   NATURE

Bypassing cancer drug resistance by activating multiple death pathways – A proposal from the study of circumventing cancer drug resistance by induction of necroptosis

(2007) Xun Hu et al.   CANCER LETTERS