An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance
Authors
Keywords
-
Journal
Oncogenesis
Volume 8, Issue 3, Pages -
Publisher
Springer Nature
Online
2019-02-19
DOI
10.1038/s41389-019-0125-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration
- (2018) Nicole M. Aiello et al. DEVELOPMENTAL CELL
- ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+T cell fates
- (2018) Tianxia Guan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis
- (2016) Masayuki Fujii et al. Cell Stem Cell
- Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer
- (2016) Sameerah Shaheen et al. Stem Cell Reviews and Reports
- Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer
- (2016) Sameerah Shaheen et al. Stem Cell Reviews and Reports
- Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer
- (2015) J A Galván et al. BRITISH JOURNAL OF CANCER
- Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
- (2015) Marc van de Wetering et al. CELL
- Transcriptional repressor ZEB2 promotes terminal differentiation of CD8 + effector and memory T cell populations during infection
- (2015) Kyla D. Omilusik et al. JOURNAL OF EXPERIMENTAL MEDICINE
- FBW7 increases drug sensitivity to cisplatin in human nasopharyngeal carcinoma by downregulating the expression of multidrug resistance-associated protein
- (2015) Yan Song et al. TUMOR BIOLOGY
- Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer
- (2015) Silvia Prislei et al. Oncotarget
- CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis
- (2014) Matilde Todaro et al. Cell Stem Cell
- Rapamycin inhibits FBXW7 loss-induced epithelial–mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells
- (2013) Yuli Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour–stroma interaction
- (2013) T Nagasaki et al. BRITISH JOURNAL OF CANCER
- Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1
- (2013) Jia Lu et al. CANCER CELL
- Investigation of the atypicalFBXW7mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines
- (2013) Hayley Davis et al. GUT
- Protein Expression of ZEB2 in Renal Cell Carcinoma and Its Prognostic Significance in Patient Survival
- (2013) Yong Fang et al. PLoS One
- Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
- (2013) M. A. Nieto SCIENCE
- Interactions between Twist and other core epithelial–mesenchymal transition factors are controlled by GSK3-mediated phosphorylation
- (2013) Rachel Lander et al. Nature Communications
- ZEB2 upregulates integrin α5 expression through cooperation with Sp1 to induce invasion during epithelial–mesenchymal transition of human cancer cells
- (2012) Eun-Hee Nam et al. CARCINOGENESIS
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- ZEB2 Promotes the Metastasis of Gastric Cancer and Modulates Epithelial Mesenchymal Transition of Gastric Cancer Cells
- (2012) Ying-Huan Dai et al. DIGESTIVE DISEASES AND SCIENCES
- ZEB2 Mediates Multiple Pathways Regulating Cell Proliferation, Migration, Invasion, and Apoptosis in Glioma
- (2012) Songtao Qi et al. PLoS One
- The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization
- (2011) S. Goossens et al. BLOOD
- ZEB proteins link cell motility with cell cycle control and cell survival in cancer
- (2011) Gareth Browne et al. CELL CYCLE
- The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
- (2011) Anna Merlos-Suárez et al. Cell Stem Cell
- Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells
- (2011) Erika Pastrana et al. Cell Stem Cell
- Overexpression of ZEB2 at the Invasion Front of Colorectal Cancer Is an Independent Prognostic Marker and Regulates Tumor Invasion In Vitro
- (2011) C. Kahlert et al. CLINICAL CANCER RESEARCH
- Emerging roles of the FBW7 tumour suppressor in stem cell differentiation
- (2011) Zhiwei Wang et al. EMBO REPORTS
- The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1
- (2011) Rachel Lander et al. JOURNAL OF CELL BIOLOGY
- p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
- (2011) Taewan Kim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation
- (2011) Roya Babaei-Jadidi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
- (2010) Neta Erez et al. CANCER CELL
- A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts
- (2010) Ronghui Li et al. Cell Stem Cell
- F-box and WD Repeat Domain-Containing 7 Regulates Intestinal Cell Lineage Commitment and Is a Haploinsufficient Tumor Suppressor
- (2010) Rocio Sancho et al. GASTROENTEROLOGY
- Colorectal cancer
- (2010) David Cunningham et al. LANCET
- Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
- (2010) Louis Vermeulen et al. NATURE CELL BIOLOGY
- Genomic Alterations in Tumor Stroma
- (2009) C. Eng et al. CANCER RESEARCH
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
- (2009) Ulrich Wellner et al. NATURE CELL BIOLOGY
- Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors
- (2009) Eve Seuntjens et al. NATURE NEUROSCIENCE
- SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer
- (2009) A. E. Sayan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence
- (2008) Stéphane Ansieau et al. CANCER CELL
- The role of the ZEB family of transcription factors in development and disease
- (2008) C. Vandewalle et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2
- (2008) Manav Korpal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
- LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis
- (2008) Pekka Katajisto et al. NATURE GENETICS
- Transcriptional regulation of cell polarity in EMT and cancer
- (2008) G Moreno-Bueno et al. ONCOGENE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now