TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy
Authors
Keywords
-
Journal
Science Immunology
Volume 6, Issue 65, Pages -
Publisher
American Association for the Advancement of Science (AAAS)
Online
2021-11-20
DOI
10.1126/sciimmunol.abi8823
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Developmental cell programs are co-opted in inflammatory skin disease
- (2021) Gary Reynolds et al. SCIENCE
- Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist
- (2021) Qingran Li et al. BMC IMMUNOLOGY
- Interleukin 17 Promotes Expression of Alarmins S100A8 and S100A9 During the Inflammatory Response of Keratinocytes
- (2021) Carolin Christmann et al. Frontiers in Immunology
- Pathophysiology of psoriasis: A review
- (2021) Keiichi Yamanaka et al. JOURNAL OF DERMATOLOGY
- Clinical and histopathological characterization of eczematous eruptions occurring in course of anti IL-17 treatment: a case series and review of the literature
- (2020) G. Caldarola et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Efficacy and safety of risankizumab in psoriasis patients who failed anti‐IL ‐17, anti‐12/23 and/or anti IL ‐23: preliminary data of a real‐life 16‐week retrospective study
- (2020) Matteo Megna et al. Dermatologic Therapy
- Animal models of psoriasis—highlights and drawbacks
- (2020) Michael P. Schön et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Risk of tuberculosis reactivation with IL‐17 and IL‐23 inhibitors in psoriasis ‐ time for a paradigm change
- (2020) Miguel Nogueira et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- IL-36 signaling in keratinocytes controls early IL-23 production in psoriasis-like dermatitis
- (2020) Jérémie D Goldstein et al. Life Science Alliance
- Involvement of the cytokine TWEAK in the pathogenesis of psoriasis vulgaris, pustular psoriasis, and erythrodermic psoriasis
- (2020) Huixia Wang et al. CYTOKINE
- Synergistic induction of IL-23 by TNFα, IL-17A, and EGF in keratinocytes
- (2020) Benjamin Ehst et al. CYTOKINE
- Atopic dermatitis is an IL-13 dominant disease with greater molecular heterogeneity compared to psoriasis
- (2019) Lam C. Tsoi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Imiquimod-Induced Psoriasis in Mice Depends on the IL-17 Signaling of Keratinocytes
- (2019) Sonja Moos et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Adaptive and Innate Immunity in Psoriasis and Other Inflammatory Disorders
- (2019) Michael P. Schön Frontiers in Immunology
- Limitations of current monoclonal antibodies for plaque-type psoriasis and an outlook for the future
- (2018) Annunziata Raimondo et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-α/IFN-γ-induced inflammatory response in keratinocytes and T cell-derived IL-17
- (2018) Ze-Min Lin et al. PHARMACOLOGICAL RESEARCH
- The Interplay Between Keratinocytes and Immune Cells in the Pathogenesis of Psoriasis
- (2018) Cristina Albanesi et al. Frontiers in Immunology
- Safety and tolerability of adalimumab for the treatment of psoriasis: a review summarizing 15 years of real-life experience
- (2018) Paul Sator Therapeutic Advances in Chronic Disease
- Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis
- (2018) Jason E. Hawkes et al. JOURNAL OF IMMUNOLOGY
- The small molecule rhodomyrtone suppresses TNF-α and IL-17A-induced keratinocyte inflammatory responses: A potential new therapeutic for psoriasis
- (2018) Julalak Chorachoo et al. PLoS One
- Fn14 deficiency ameliorates psoriasis-like skin disease in a murine model
- (2018) L. Peng et al. Cell Death & Disease
- Psoriasis: Keratinocytes or Immune Cells – Which Is the Trigger?
- (2018) Farida Benhadou et al. DERMATOLOGY
- Psoriasis pathogenesis and the development of novel targeted immune therapies
- (2017) Jason E. Hawkes et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Impact of immunogenicity on response to anti-TNF therapy in moderate-to-severe plaque psoriasis: results of the PREDIR study
- (2017) Mariano Ara-Martín et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
- (2017) Daniel Sidler et al. Nature Communications
- RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin
- (2017) William R. Swindell et al. Scientific Reports
- Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis
- (2017) William R. Swindell et al. Genome Medicine
- Serum levels of TWEAK in patients with psoriasis vulgaris
- (2016) Özlem Bilgiç et al. CYTOKINE
- Fn14 deficiency protects lupus-prone mice from histological lupus erythematosus-like skin inflammation induced by ultraviolet light
- (2016) Jessica Doerner et al. EXPERIMENTAL DERMATOLOGY
- Topical imiquimod yields systemic effects due to unintended oral uptake
- (2016) Lynda Grine et al. Scientific Reports
- Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation
- (2016) Hideaki Takagi et al. Scientific Reports
- TWEAK/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation
- (2015) Hong Cheng et al. EXPERIMENTAL DERMATOLOGY
- TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus
- (2015) Jessica L. Doerner et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Alarmin Function of Cathelicidin Antimicrobial Peptide LL37 through IL-36γ Induction in Human Epidermal Keratinocytes
- (2014) Na Li et al. JOURNAL OF IMMUNOLOGY
- Psoriasis prevalence among adults in the United States
- (2014) Tara D. Rachakonda et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- TWEAK/Fn14 axis: The current paradigm of tissue injury-inducible function in the midst of complexities
- (2014) Linda C. Burkly SEMINARS IN IMMUNOLOGY
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Anti-TWEAK Monoclonal Antibody in Patients With Rheumatoid Arthritis
- (2013) Nicolas Wisniacki et al. CLINICAL THERAPEUTICS
- TWEAK/Fn14 pathway promotes a T helper 2-type chronic colitis with fibrosis in mice
- (2013) A Son et al. Mucosal Immunology
- Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling
- (2013) T. G. Bird et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aldara activates TLR7-independent immune defence
- (2013) Anne Walter et al. Nature Communications
- Novel insights into the role of S100A8/A9 in skin biology
- (2012) Claus Kerkhoff et al. EXPERIMENTAL DERMATOLOGY
- Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis
- (2012) Craig Leonardi et al. NEW ENGLAND JOURNAL OF MEDICINE
- TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses
- (2011) Linda C. Burkly et al. IMMUNOLOGICAL REVIEWS
- Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
- (2010) Andrea Chiricozzi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- TWEAK as a target for therapy in systemic lupus erythematosus
- (2010) Rui-Xue Leng et al. MOLECULAR BIOLOGY REPORTS
- Evaluation of the Psoriasis Transcriptome across Different Studies by Gene Set Enrichment Analysis (GSEA)
- (2010) Mayte Suárez-Fariñas et al. PLoS One
- Type I Interferon: Potential Therapeutic Target for Psoriasis?
- (2008) Yihong Yao et al. PLoS One
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started