Efficient Messenger RNA Delivery to the Kidney Using Renal Pelvis Injection in Mice

Treatment of ischemic neuronal death by introducing brain-derived neurotrophic factor mRNA using polyplex nanomicelle

(2021) Yuta Fukushima et al.   BIOMATERIALS

Effectiveness of mRNA COVID-19 vaccines against SARS-CoV-2 infection in a cohort of healthcare personnel

(2021) Melanie D Swift et al.   CLINICAL INFECTIOUS DISEASES

Effects of Tissue Pressure on Transgene Expression Characteristics via Renal Local Administration Routes from Ureter or Renal Artery in the Rat Kidney

(2020) Natsuko Oyama et al.   Pharmaceutics

Gene therapy research for kidney diseases

(2019) Lori Davis et al.   PHYSIOLOGICAL GENOMICS

Enhancement of Motor Function Recovery after Spinal Cord Injury in Mice by Delivery of Brain-Derived Neurotrophic Factor mRNA

(2019) Samuel T. Crowley et al.   Molecular Therapy-Nucleic Acids

Hydrodynamic Renal Pelvis Injection for Non-viral Expression of Proteins in the Kidney

(2018) Lauren E. Woodard et al.   Jove-Journal of Visualized Experiments

Pseudoginsengenin DQ Exhibits Therapeutic Effects in Cisplatin-Induced Acute Kidney Injury via Sirt1/NF-κB and Caspase Signaling Pathway without Compromising Its Antitumor Activity in Mice

(2018) Zeng Qi et al.   MOLECULES

Kidney-specific transposon-mediated gene transfer in vivo

(2017) Lauren E. Woodard et al.   Scientific Reports

Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles

(2016) Chin-Yu Lin et al.   JOURNAL OF CONTROLLED RELEASE

Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment

(2016) Hailati Aini et al.   Scientific Reports

Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles

(2015) Miyuki Baba et al.   JOURNAL OF CONTROLLED RELEASE

Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases

(2015) Akitsugu Matsui et al.   Scientific Reports

Modulated Protonation of Side Chain Aminoethylene Repeats in N-Substituted Polyaspartamides Promotes mRNA Transfection

(2014) Hirokuni Uchida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule–specific knockout mouse models

(2013) Qingqing Wei et al.   KIDNEY INTERNATIONAL

Biomarkers for Drug-Induced Renal Damage and Nephrotoxicity—An Overview for Applied Toxicology

(2011) Tobias Christian Fuchs et al.   AAPS Journal

Progress and Prospects of Polyplex Nanomicelles for Plasmid DNA Delivery

(2011) Keiji Itaka et al.   CURRENT GENE THERAPY

Effect of Three Types of Mixed Anesthetic Agents Alternate to Ketamine in Mice

(2011) Sumiko KAWAI et al.   EXPERIMENTAL ANIMALS

Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice

(2011) Shigehiro Doi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Key Physiological Phenomena Governing Transgene Expression Based on Tissue Pressure-Mediated Transfection in Mice

(2010) Hidefumi Mukai et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity

(2010) Keiji Itaka et al.   BIOMATERIALS

Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery

(2010) Makoto Oba et al.   BIOMATERIALS

Renal press-mediated transfection method for plasmid DNA and siRNA to the kidney

(2008) Hidefumi Mukai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS