Metabolic Molecule PLA2G2D Is a Potential Prognostic Biomarker Correlating With Immune Cell Infiltration and the Expression of Immune Checkpoint Genes in Cervical Squamous Cell Carcinoma

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers

(2021) Nisha B. Nagarsheth et al.   NATURE MEDICINE

Tumor Immune Microenvironment Characteristics and Their Prognostic Value in Non-Small-Cell Lung Cancer

(2021) Dan Su et al.   Frontiers in Oncology

Identification of a tumor microenvironment-related gene signature to improve the prediction of cervical cancer prognosis

(2021) Qian Chen et al.   Cancer Cell International

A Novel Risk Model Based on Lipid Metabolism-Associated Genes Predicts Prognosis and Indicates Immune Microenvironment in Breast Cancer

(2021) Zhimin Ye et al.   Frontiers in Cell and Developmental Biology

The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies

(2020) Florent Petitprez et al.   Frontiers in Immunology

Metabolic Modulation of the Tumor Microenvironment Leads to Multiple Checkpoint Inhibition and Immune Cell Infiltration

(2020) David Kolb et al.   ACS Nano

A Five-Gene Signature Based on Stromal/Immune Scores in the Tumor Microenvironment and Its Clinical Implications for Liver Cancer

(2020) Xichun Liu et al.   DNA AND CELL BIOLOGY

Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes

(2020) Alessia Gagliardi et al.   NATURE GENETICS

Prognostic value of lipid metabolism‐related genes in head and neck squamous cell carcinoma

(2020) Ying Xiong et al.   Immunity Inflammation and Disease

Cervical cancer

(2019) Paul A Cohen et al.   LANCET

Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study

(2019) Hyun Cheol Chung et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety and efficacy of adoptive cell transfer using autologous tumor infiltrating lymphocytes (LN-145) for treatment of recurrent, metastatic, or persistent cervical carcinoma.

(2019) Amir A. Jazaeri et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

(2019) Francesca Finotello et al.   Genome Medicine

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

(2019) Robert D. Leone et al.   SCIENCE

The prognostic landscape of tumor-infiltrating immune cells in cervical cancer

(2019) Jingnan Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Immune cells within the tumor microenvironment: Biological functions and roles in cancer immunotherapy

(2019) Xu Lei et al.   CANCER LETTERS

Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response

(2019) Shamir Cassim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lymphatic Dysfunction, Leukotrienes, and Lymphedema

(2018) Xinguo Jiang et al.   Annual Review of Physiology

Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy

(2018) Jinyang Li et al.   IMMUNITY

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

Association of Ipilimumab With Safety and Antitumor Activity in Women With Metastatic or Recurrent Human Papillomavirus–Related Cervical Carcinoma

(2018) Stephanie Lheureux et al.   JAMA Oncology

Classification of triple-negative breast cancers based on Immunogenomic profiling

(2018) Yin He et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Safety and Efficacy of Pembrolizumab in Advanced, Programmed Death Ligand 1–Positive Cervical Cancer: Results From the Phase Ib KEYNOTE-028 Trial

(2017) Jean-Sebastien Frenel et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis

(2017) Alexandra Snyder et al.   PLOS MEDICINE

Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data

(2017) Julien Racle et al.   eLife

Dual Roles of Group IID Phospholipase A2in Inflammation and Cancer

(2016) Yoshimi Miki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Predictive biomarkers for checkpoint inhibitor-based immunotherapy

(2016) Geoffrey T Gibney et al.   LANCET ONCOLOGY

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Critical role of phospholipase A2group IID in age-related susceptibility to severe acute respiratory syndrome–CoV infection

(2015) Rahul Vijay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

(2015) Zheng Hu et al.   NATURE GENETICS

The Need for Improvement of the Treatment of Advanced and Metastatic Cervical Cancer, the Rationale for Combined Chemo-Immunotherapy

(2014) Helene Meir et al.   Anti-Cancer Agents in Medicinal Chemistry

Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

(2014) Brian Ruffell et al.   CANCER CELL

New Strategies in Advanced Cervical Cancer: From Angiogenesis Blockade to Immunotherapy

(2014) K. S. Tewari et al.   CLINICAL CANCER RESEARCH

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

(2014) Roy S. Herbst et al.   NATURE

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

Improved Survival with Bevacizumab in Advanced Cervical Cancer

(2014) Krishnansu S. Tewari et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lymphoid tissue phospholipase A2group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators

(2013) Yoshimi Miki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

Oncogenic BRAF(V600E) Promotes Stromal Cell-Mediated Immunosuppression Via Induction of Interleukin-1 in Melanoma

(2012) J. S. Khalili et al.   CLINICAL CANCER RESEARCH

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

(2011) David G. DeNardo et al.   Cancer Discovery

Macrophage Expression of Hypoxia-Inducible Factor-1  Suppresses T-Cell Function and Promotes Tumor Progression

(2010) A. L. Doedens et al.   CANCER RESEARCH

Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+regulatory T cells

(2009) Caroline E. von Allmen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival

(2009) D. Bogunovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate

(2008) C M Mounier et al.   BRITISH JOURNAL OF CANCER