β-Elemene Restrains PTEN mRNA Degradation to Restrain the Growth of Lung Cancer Cells via METTL3-Mediated N6 Methyladenosine Modification

miR-600 inhibits lung cancer via downregulating the expression of METTL3

(2019) Wenwen Wei et al.   Cancer Management and Research

Molecular targets of β-elemene, a herbal extract used in traditional Chinese medicine, and its potential role in cancer therapy: A review

(2019) Bingtao Zhai et al.   BIOMEDICINE & PHARMACOTHERAPY

β‐Elemene inhibits peritoneal metastasis of gastric cancer cells by modulating FAK/Claudin‐1 signaling

(2019) Mingming Deng et al.   PHYTOTHERAPY RESEARCH

PTEN Tumor-Suppressor: The Dam of Stemness in Cancer

(2019) Francesca Luongo et al.   Cancers

PTEN in Lung Cancer: Dealing with the Problem, Building on New Knowledge and Turning the Game Around

(2019) Anastasios Gkountakos et al.   Cancers

LncRNA LINC00470 promotes the degradation of PTEN mRNA to facilitate malignant behavior in gastric cancer cells

(2019) Jijun Yan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer

(2019) Ben Yue et al.   Molecular Cancer

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Role of N 6 -methyladenosine modification in cancer

(2018) Xiaolan Deng et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Zc3h13 Regulates Nuclear RNA m 6 A Methylation and Mouse Embryonic Stem Cell Self-Renewal

(2018) Jing Wen et al.   MOLECULAR CELL

miR-142-5p regulates CD4+ T cells in human non-small cell lung cancer through PD-L1 expression via the PTEN pathway

(2018) Jun Wan et al.   ONCOLOGY REPORTS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis

(2018) Junho Choe et al.   NATURE

β‑elemene induced anticancer effect in bladder cancer through upregulation of PTEN and suppression of AKT phosphorylation

(2018) Bo Cai et al.   Oncology Letters

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

(2018) J. Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Drug delivery systems for elemene, its main active ingredient β-elemene, and its derivatives in cancer therapy

(2018) Bingtao Zhai et al.   International Journal of Nanomedicine

Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation

(2018) Xiang Zhong et al.   Cell Reports

MicroRNA-145 ModulatesN6-Methyladenosine Levels by Targeting the 3′-Untranslated mRNA Region of theN6-Methyladenosine Binding YTH Domain Family 2 Protein

(2017) Zhe Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing

(2017) Marek Bartosovic et al.   NUCLEIC ACIDS RESEARCH

N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein

(2017) Nian Liu et al.   NUCLEIC ACIDS RESEARCH

Anticancer effects of β-elemene with hyperthermia in lung cancer cells

(2017) Zhibing Wu et al.   Experimental and Therapeutic Medicine

β-Elemene: Mechanistic Studies on Cancer Cell Interaction and Its Chemosensitization Effect

(2017) Ziyu Jiang et al.   Frontiers in Pharmacology

Review of the use of pretest probability for molecular testing in non-small cell lung cancer and overview of new mutations that may affect clinical practice

(2017) Petra Martin et al.   Therapeutic Advances in Medical Oncology

The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics

(2016) Ting-Yuan David Cheng et al.   Journal of Thoracic Oncology

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Epigenetic mechanisms in neurogenesis

(2016) Bing Yao et al.   NATURE REVIEWS NEUROSCIENCE

Nivolumab in the treatment of metastatic squamous non-small cell lung cancer: a review of the evidence

(2016) Joline S. J. Lim et al.   Therapeutic Advances in Respiratory Disease

β-elemene inhibited expression of DNA methyltransferase 1 through activation of ERK1/2 and AMPKα signalling pathways in human lung cancer cells: the role of Sp1

(2015) ShunYu Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

N6-methyladenosine marks primary microRNAs for processing

(2015) Claudio R. Alarcón et al.   NATURE

β-elemene enhances both radiosensitivity and chemosensitivity of glioblastoma cells through the inhibition of the ATM signaling pathway

(2015) SIWEI LIU et al.   ONCOLOGY REPORTS

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Molecular pathways and therapeutic targets in lung cancer

(2015) Emma Shtivelman et al.   Oncotarget

β-Elemene Induces Apoptosis in Human Renal-cell Carcinoma 786-0 Cells through Inhibition of MAPK/ERK and PI3K/Akt/mTOR Signalling Pathways

(2012) Yun-Hong Zhan et al.   Asian Pacific Journal of Cancer Prevention

Higher numbers of T-bet+ intratumoral lymphoid cells correlate with better survival in gastric cancer

(2012) Lu-jun Chen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis

(2011) Jing Liu et al.   BMC CANCER

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

β-Elemene Radiosensitizes Lung Cancer A549 Cells by Enhancing DNA Damage and Inhibiting DNA Repair

(2011) Long-Jie Li et al.   PHYTOTHERAPY RESEARCH

Anti-cancer natural products isolated from chinese medicinal herbs

(2011) Wen Tan et al.   Chinese Medicine

Antineoplastic effect ofβ-elemene on prostate cancer cells and other types of solid tumour cells

(2010) Qingdi Quentin Li et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Anti-tumor effect of β-elemene in glioblastoma cells depends on p38 MAPK activation

(2008) Yi-Qun Yao et al.   CANCER LETTERS