Neutrophils Extracellular Traps Inhibition Improves PD-1 Blockade Immunotherapy in Colorectal Cancer

Cancer Statistics, 2021

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Platelet TLR4-ERK5 axis facilitates NET-mediated capturing of circulating tumor cells and distant metastasis after surgical stress

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Neutrophil Extracellular Traps in Colorectal Cancer Progression and Metastasis

(2021) Umama Khan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increased neutrophil extracellular traps promote metastasis potential of hepatocellular carcinoma via provoking tumorous inflammatory response

(2020) Lu-Yu Yang et al.   Journal of Hematology & Oncology

Targeting circulating SINEs and LINEs with DNase I provides metastases inhibition in experimental tumor models

(2020) L.A. Alekseeva et al.   Molecular Therapy-Nucleic Acids

Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells

(2020) Š. Bálint et al.   SCIENCE

Hepatic Surgical Stress Promotes Systemic Immunothrombosis That Results in Distant Organ Injury

(2020) Hongji Zhang et al.   Frontiers in Immunology

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25

(2020) Linbin Yang et al.   NATURE

AAV‐mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response

(2020) Yujia Xia et al.   Molecular Oncology

The Emerging Role of Neutrophil Extracellular Traps (NETs) in Tumor Progression and Metastasis

(2020) Maria Teresa Masucci et al.   Frontiers in Immunology

Tumor-Associated Neutrophils and Macrophages—Heterogenous but Not Chaotic

(2020) Ling Wu et al.   Frontiers in Immunology

Immunotherapy in colorectal cancer: rationale, challenges and potential

(2019) Karuna Ganesh et al.   Nature Reviews Gastroenterology & Hepatology

The Role of Tumor-Associated Neutrophils in Colorectal Cancer

(2019) Rei Mizuno et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutrophil Extracellular Traps Drive Mitochondrial Homeostasis in Tumors to Augment Growth

(2019) Hamza O Yazdani et al.   CANCER RESEARCH

STING: a master regulator in the cancer-immunity cycle

(2019) Yuanyuan Zhu et al.   Molecular Cancer

Tumor Associated Neutrophils. Their Role in Tumorigenesis, Metastasis, Prognosis and Therapy

(2019) Maria Teresa Masucci et al.   Frontiers in Oncology

Neutrophils suppress tumor‐infiltrating T cells in colon cancer via matrix metalloproteinase‐mediated activation of TGF β

(2019) Markus Germann et al.   EMBO Molecular Medicine

Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis

(2018) Dirk J. van der Windt et al.   HEPATOLOGY

Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade–mediated tumor regression

(2018) Heng Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophils and neutrophil extracellular traps in the liver and gastrointestinal system

(2018) Masaki Honda et al.   Nature Reviews Gastroenterology & Hepatology

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

(2018) Livnat Jerby-Arnon et al.   CELL

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix

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IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade

(2017) Mark Ayers et al.   JOURNAL OF CLINICAL INVESTIGATION

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

(2017) Vikram R. Juneja et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Combination therapy strategies for improving PD-1 blockade efficacy: a new era in cancer immunotherapy

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Elements of cancer immunity and the cancer–immune set point

(2017) Daniel S. Chen et al.   NATURE

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

Combination immunotherapy: a road map

(2017) Patrick A. Ott et al.   Journal for ImmunoTherapy of Cancer

Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress

(2016) Samer Tohme et al.   CANCER RESEARCH

Immunology in the liver — from homeostasis to disease

(2016) Felix Heymann et al.   Nature Reviews Gastroenterology & Hepatology

Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps

(2016) J. Park et al.   Science Translational Medicine

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

(2016) Weiping Zou et al.   Science Translational Medicine

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

(2016) P.-L. Chen et al.   Cancer Discovery

Activated STING enhances Tregs infiltration in the HPV-related carcinogenesis of tongue squamous cells via the c-jun/CCL22 signal

(2015) Ding Liang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Damage-associated molecular pattern-activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury

(2015) Hai Huang et al.   HEPATOLOGY

A reproducible method for the expansion of mouse CD8 + T lymphocytes

(2015) Mark D. Lewis et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Combination cancer immunotherapy and new immunomodulatory targets

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Toll-like receptor 9 agonist enhances anti-tumor immunity and inhibits tumor-associated immunosuppressive cells numbers in a mouse cervical cancer model following recombinant lipoprotein therapy

(2014) Li-Sheng Chang et al.   Molecular Cancer

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

A proposed role for neutrophil extracellular traps in cancer immunoediting

(2013) Sivan Berger-Achituv et al.   Frontiers in Immunology

Autocrine IFN-  Promotes Naive CD8 T Cell Differentiation and Synergizes with IFN-  To Stimulate Strong Function

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Hallmarks of Cancer: The Next Generation

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Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps

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Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

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