Interplay between Genome, Metabolome and Microbiome in Colorectal Cancer

Large-scale association analyses identify host factors influencing human gut microbiome composition

(2021) Alexander Kurilshikov et al.   NATURE GENETICS

Integrative Analysis of Fecal Metagenomics and Metabolomics in Colorectal Cancer

(2020) Marc Clos-Garcia et al.   Cancers

Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

(2020) Minta Thomas et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Integration of genomics, metagenomics, and metabolomics to identify interplay between susceptibility alleles and microbiota in adenoma initiation

(2020) Jacob E. Moskowitz et al.   BMC CANCER

Host–microbiota maladaptation in colorectal cancer

(2020) Alina Janney et al.   NATURE

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

(2019) Philip J. Law et al.   Nature Communications

PRSice-2: Polygenic Risk Score software for biobank-scale data

(2019) Shing Wan Choi et al.   GigaScience

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

(2019) Sunny H. Wong et al.   Nature Reviews Gastroenterology & Hepatology

Modifiable pathways for colorectal cancer: a mendelian randomisation analysis

(2019) Alex J Cornish et al.   Lancet Gastroenterology & Hepatology

Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) and its receptor PROKR2 are associated to human colorectal cancer progression and peritoneal carcinomatosis

(2018) Mohammed Benlahfid et al.   Cancer Biomarkers

Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets

(2018) Ricard Argelaguet et al.   Molecular Systems Biology

Causal associations between risk factors and common diseases inferred from GWAS summary data

(2018) Zhihong Zhu et al.   Nature Communications

Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis

(2018) Megan E. Forrest et al.   Scientific Reports

Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

(2018) Michael B. Burns et al.   PLoS Genetics

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer

(2018) Joaquin Cubiella et al.   Cancers

Functional evaluation of alternative splicing in the FAM190A gene

(2018) Sung Ung Kang et al.   Genes & Genomics

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

(2017) Henry Rodriguez-Broadbent et al.   INTERNATIONAL JOURNAL OF CANCER

Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study

(2017) Gemma Ibáñez-Sanz et al.   Scientific Reports

Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients

(2016) Joaquín Cubiella et al.   BMC Medicine

Inflammatory networks underlying colorectal cancer

(2016) Audrey Lasry et al.   NATURE IMMUNOLOGY

Blood lipids and colorectal polyps: testing an etiologic hypothesis using phenotypic measurements and Mendelian randomization

(2015) Michael N. Passarelli et al.   CANCER CAUSES & CONTROL

Methods of integrating data to uncover genotype–phenotype interactions

(2015) Marylyn D. Ritchie et al.   NATURE REVIEWS GENETICS

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

FAM190A Deficiency Creates a Cell Division Defect

(2013) Kalpesh Patel et al.   AMERICAN JOURNAL OF PATHOLOGY

Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins

(2011) Anna Abulí et al.   BMC CANCER

A Large Prospective Study of Meat Consumption and Colorectal Cancer Risk: An Investigation of Potential Mechanisms Underlying this Association

(2010) A. J. Cross et al.   CANCER RESEARCH

Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer Phenotype

(2010) Anna Abulí et al.   GASTROENTEROLOGY

Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology

(2008) B. Levin et al.   CA-A CANCER JOURNAL FOR CLINICIANS