Identification of novel GPCR partners of the central melanocortin signaling

Pharmacological evaluation of MRAP proteins on Xenopus neural melanocortin signaling

(2021) Xiaolu Tai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Peripheral actions and direct central–local communications of melanocortin 4 receptor signaling

(2021) Lei Li et al.   Journal of Sport and Health Science

MRAP2 Interaction with Melanocortin-4 Receptor in SnakeHead (Channa argus)

(2021) Zheng-Yong Wen et al.   Biomolecules

Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice

(2020) Fangfang Han et al.   CELL RESEARCH

Molecular chaperones and G protein-coupled receptor maturation and pharmacology

(2020) Ya-Xiong Tao   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Single‐cell RNA sequencing analysis of human kidney reveals the presence of ACE2 receptor: A potential pathway of COVID‐19 infection

(2020) Qiyu He et al.   Molecular Genetics & Genomic Medicine

Pharmacological modulation of MRAP2 protein on melanocortin receptors in the sea lamprey

(2019) Ming Zhu et al.   Endocrine Connections

Single-cell transcriptomic analysis of the lateral hypothalamic area reveals molecularly distinct populations of inhibitory and excitatory neurons

(2019) Laura E. Mickelsen et al.   NATURE NEUROSCIENCE

Hypothalamic inflammation and obesity: a mechanistic review

(2019) Jichang Seong et al.   ARCHIVES OF PHARMACAL RESEARCH

Obesity remodels activity and transcriptional state of a lateral hypothalamic brake on feeding

(2019) Mark A. Rossi et al.   SCIENCE

Integrated analysis of lncRNA-miRNA-mRNA ceRNA network in squamous cell carcinoma of tongue

(2019) Rui-Sheng Zhou et al.   BMC CANCER

Pharmacological modulation of melanocortin-4 receptor by melanocortin receptor accessory protein 2 in Nile tilapia

(2019) Meng Wang et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Melanocortin Regulation of Inflammation

(2019) Wei Wang et al.   Frontiers in Endocrinology

Overlapping Brain Circuits for Homeostatic and Hedonic Feeding

(2018) Mark A. Rossi et al.   Cell Metabolism

Toward a Wiring Diagram Understanding of Appetite Control

(2017) Mark L. Andermann et al.   NEURON

Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity

(2017) Renchao Chen et al.   Cell Reports

GPR88 is a critical regulator of feeding and body composition in mice

(2017) Jackie Lau et al.   Scientific Reports

Biased signaling initiated by agouti-related peptide through human melanocortin-3 and -4 receptors

(2016) Zhao Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Evolution of physicochemical properties of melanin concentrating hormone receptor 1 (MCHr1) antagonists

(2016) Anders Johansson   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

60 YEARS OF POMC: Regulation of feeding and energy homeostasis by α-MSH

(2016) Erica J P Anderson et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

(2016) Roman A Romanov et al.   NATURE NEUROSCIENCE

The Melanocortin-4 Receptor Is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-like Peptide 1 In Vivo

(2014) Brandon L. Panaro et al.   Cell Metabolism

GPRC5B a putative glutamate-receptor candidate is negative modulator of insulin secretion

(2013) Arvind Soni et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prostaglandin E2 acts via bone marrow macrophages to block PTH-stimulated osteoblast differentiation in vitro

(2013) Shilpa Choudhary et al.   BONE

Oxytocin Receptor in the Hypothalamus Is Sufficient to Rescue Normal Thermoregulatory Function in Male Oxytocin Receptor Knockout Mice

(2013) Yoshiyuki Kasahara et al.   ENDOCRINOLOGY

Melanocortin-4 receptor mutations paradoxically reduce preference for palatable foods

(2013) B. L. Panaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental Control of the Melanocortin-4 Receptor by MRAP2 Proteins in Zebrafish

(2013) J. A. Sebag et al.   SCIENCE

Neuronal circuits that regulate feeding behavior and metabolism

(2013) Jong-Woo Sohn et al.   TRENDS IN NEUROSCIENCES

GPCR Heterodimerization in the Reproductive System: Functional Regulation and Implication for Biodiversity

(2013) Honoo Satake et al.   Frontiers in Endocrinology

AgRP and POMC Neurons Are Hypophysiotropic and Coordinately Regulate Multiple Endocrine Axes in a Larval Teleost

(2012) Chao Zhang et al.   Cell Metabolism

PTGS-2-PTGER2/4 Signaling Pathway Partially Protects From Diabetogenic Toxicity of Streptozotocin in Mice

(2012) A. Vennemann et al.   DIABETES

Deconstruction of a neural circuit for hunger

(2012) Deniz Atasoy et al.   NATURE

Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR

(2012) Baran A Ersoy et al.   Nature Chemical Biology

Melanocortin-3 receptor regulates the normal fasting response

(2012) B. J. Renquist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central nervous control of energy and glucose balance: focus on the central melanocortin system

(2011) Yong Xu et al.   Annals of the New York Academy of Sciences

Physiological roles of the melanocortin MC3 receptor

(2011) Benjamin J. Renquist et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mutually Opposite Signal Modulation by Hypothalamic Heterodimerization of Ghrelin and Melanocortin-3 Receptors

(2011) Anne Rediger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Allostery at G Protein-Coupled Receptor Homo- and Heteromers: Uncharted Pharmacological Landscapes

(2010) N. J. Smith et al.   PHARMACOLOGICAL REVIEWS

Therapeutic potential of β-arrestin- and G protein-biased agonists

(2010) Erin J. Whalen et al.   TRENDS IN MOLECULAR MEDICINE

Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons

(2009) Hind Al-Qassab et al.   Cell Metabolism

Proopiomelanocortin Expression in both GABA and Glutamate Neurons

(2009) S. T. Hentges et al.   JOURNAL OF NEUROSCIENCE

5-HT2CRs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis

(2008) Yong Xu et al.   NEURON