Obesity remodels activity and transcriptional state of a lateral hypothalamic brake on feeding

Punishment-Predictive Cues Guide Avoidance through Potentiation of Hypothalamus-to-Habenula Synapses

(2019) Massimo Trusel et al.   NEURON

Single-cell transcriptomic analysis of the lateral hypothalamic area reveals molecularly distinct populations of inhibitory and excitatory neurons

(2019) Laura E. Mickelsen et al.   NATURE NEUROSCIENCE

A hypothalamus-habenula circuit controls aversion

(2019) Iakovos Lazaridis et al.   MOLECULAR PSYCHIATRY

Overlapping Brain Circuits for Homeostatic and Hedonic Feeding

(2018) Mark A. Rossi et al.   Cell Metabolism

Genetic identification of brain cell types underlying schizophrenia

(2018) Nathan G. Skene et al.   NATURE GENETICS

Prefrontal cortex output circuits guide reward seeking through divergent cue encoding

(2017) James M. Otis et al.   NATURE

Hormonal gain control of a medial preoptic area social reward circuit

(2017) Jenna A McHenry et al.   NATURE NEUROSCIENCE

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity

(2017) Renchao Chen et al.   Cell Reports

Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward

(2016) A. M. Stamatakis et al.   JOURNAL OF NEUROSCIENCE

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Visualization of cortical, subcortical and deep brain neural circuit dynamics during naturalistic mammalian behavior with head-mounted microscopes and chronically implanted lenses

(2016) Shanna L Resendez et al.   Nature Protocols

Inhibitory Input from the Lateral Hypothalamus to the Ventral Tegmental Area Disinhibits Dopamine Neurons and Promotes Behavioral Activation

(2016) Edward H. Nieh et al.   NEURON

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Decoding Neural Circuits that Control Compulsive Sucrose Seeking

(2015) Edward H. Nieh et al.   CELL

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Visualizing Hypothalamic Network Dynamics for Appetitive and Consummatory Behaviors

(2015) Joshua H. Jennings et al.   CELL

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

(2015) Fredrick E Henry et al.   eLife

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Accounting for technical noise in single-cell RNA-seq experiments

(2013) Philip Brennecke et al.   NATURE METHODS

The Inhibitory Circuit Architecture of the Lateral Hypothalamus Orchestrates Feeding

(2013) J. H. Jennings et al.   SCIENCE

Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments

(2012) Andrew McDavid et al.   BIOINFORMATICS

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Unsupervised pattern discovery in human chromatin structure through genomic segmentation

(2012) Michael M Hoffman et al.   NATURE METHODS

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

(2011) Mariel M Finucane et al.   LANCET

Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits

(2011) Dennis R Sparta et al.   Nature Protocols

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

(2011) Linh Vong et al.   NEURON

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS