Suppression of Transmembrane Tumor Necrosis Factor Alpha Processing by a Specific Antibody Protects Against Colitis-Associated Cancer

Inhibition of transmembrane TNF-α shedding by a specific antibody protects against septic shock

(2019) Chenxi Li et al.   Cell Death & Disease

Cardioprotective Role of Myeloid-Derived Suppressor Cells in Heart Failure

(2018) Ling Zhou et al.   CIRCULATION

Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells

(2018) Zunyue Zhang et al.   ONCOGENE

Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents

(2018) Huimin Zou et al.   Frontiers in Immunology

Transmembrane tumor necrosis factor-α promotes the recruitment of MDSCs to tumor tissue by upregulating CXCR4 expression via TNFR2

(2017) Hongping Ba et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Molecular correlates and prognostic value of tmTNF-α expression in colorectal cancer of 5-Fluorouracil-Based Adjuvant Therapy

(2016) Xiaogai Li et al.   CANCER BIOLOGY & THERAPY

Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity

(2016) Hidetoshi Nakagawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Soluble Tumor Necrosis Factor Prevents Chemically Induced Carcinogenesis in Mice

(2016) A. Sobo-Vujanovic et al.   Cancer Immunology Research

Immune and Inflammatory Cell Composition of Human Lung Cancer Stroma

(2015) G-Andre Banat et al.   PLoS One

The Risk of Colorectal Cancer in Patients with Ulcerative Colitis

(2014) Tobias M. Nowacki et al.   DIGESTIVE DISEASES AND SCIENCES

Targeting Transmembrane TNF-α Suppresses Breast Cancer Growth

(2013) Mingxia Yu et al.   CANCER RESEARCH

Transmembrane TNF-  Promotes Suppressive Activities of Myeloid-Derived Suppressor Cells via TNFR2

(2013) X. Hu et al.   JOURNAL OF IMMUNOLOGY

Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease

(2013) Ole Haagen Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

The role of pro-inflammatory cytokines and immune cells in colorectal carcinoma progression

(2013) HUANRAN LIU et al.   Oncology Letters

Tumor-Infiltrating Immune Cells Promoting Tumor Invasion and Metastasis: Existing Theories

(2013) Yan-gao Man et al.   Journal of Cancer

Neutralization of Membrane TNF, but Not Soluble TNF, Is Crucial for the Treatment of Experimental Colitis

(2012) Clémentine Perrier et al.   INFLAMMATORY BOWEL DISEASES

A Novel Murine Model of Inflammatory Bowel Disease and Inflammation-Associated Colon Cancer with Ulcerative Colitis-Like Features

(2012) Laura P. Hale et al.   PLoS One

Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis

(2009) Michio Onizawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Outside-to-inside signaling through transmembrane tumor necrosis factor reverses pathologic interleukin-1β production and deficient apoptosis of rheumatoid arthritis monocytes

(2009) Undine Meusch et al.   ARTHRITIS AND RHEUMATISM

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer

(2009) Linda A. Feagins et al.   Nature Reviews Gastroenterology & Hepatology

Expression of TNF-α leader sequence renders MCF-7 tumor cells resistant to the cytotoxicity of soluble TNF-α

(2008) Dan Yan et al.   BREAST CANCER RESEARCH AND TREATMENT

Blocking TNF-α in mice reduces colorectal carcinogenesis associated with chronic colitis

(2008) Boryana K. Popivanova et al.   JOURNAL OF CLINICAL INVESTIGATION

Risk for colorectal cancer in ulcerative colitis: Changes, causes and management strategies

(2008) Peter Laszlo Lakatos et al.   WORLD JOURNAL OF GASTROENTEROLOGY