Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 113, Issue 22, Pages 6248-6253
Publisher
Proceedings of the National Academy of Sciences
Online
2016-05-17
DOI
10.1073/pnas.1604765113
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Clonal Abundance of Tumor-Specific CD4 + T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion
- (2016) Nicole Malandro et al. IMMUNITY
- TIGIT predominantly regulates the immune response via regulatory T cells
- (2015) Sema Kurtulus et al. JOURNAL OF CLINICAL INVESTIGATION
- Helios Controls a Limited Subset of Regulatory T Cell Functions
- (2015) Mathew Sebastian et al. JOURNAL OF IMMUNOLOGY
- Combination cancer immunotherapy and new immunomodulatory targets
- (2015) Kathleen M. Mahoney et al. NATURE REVIEWS DRUG DISCOVERY
- Stable inhibitory activity of regulatory T cells requires the transcription factor Helios
- (2015) H.-J. Kim et al. SCIENCE
- GITR subverts Foxp3+ Tregs to boost Th9 immunity through regulation of histone acetylation
- (2015) Xiang Xiao et al. Nature Communications
- Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice
- (2014) J. T. Murphy et al. BLOOD
- Control of the Inheritance of Regulatory T Cell Identity by a cis Element in the Foxp3 Locus
- (2014) Yongqiang Feng et al. CELL
- Regulatory T cells in cancer immunotherapy
- (2014) Hiroyoshi Nishikawa et al. CURRENT OPINION IN IMMUNOLOGY
- Immune Modulation in Cancer with Antibodies
- (2013) David B. Page et al. Annual Review of Medicine
- Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
- (2013) Tyler R. Simpson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans
- (2013) D. Sugiyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
- (2013) S. Malchow et al. SCIENCE
- GITR Pathway Activation Abrogates Tumor Immune Suppression through Loss of Regulatory T-cell Lineage Stability
- (2013) D. A. Schaer et al. Cancer Immunology Research
- TIM3+FOXP3+regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer
- (2013) Kaori Sakuishi et al. OncoImmunology
- Induction of tumoricidal function in CD4+T cells is associated with concomitant memory and terminally differentiated phenotype
- (2012) Daniel Hirschhorn-Cymerman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tumor-reactive CD4+T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
- (2010) Sergio A. Quezada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells
- (2010) A. M. Thornton et al. JOURNAL OF IMMUNOLOGY
- PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
- (2009) Loise M. Francisco et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Helios Deficiency Has Minimal Impact on T Cell Development and Function
- (2009) Q. Cai et al. JOURNAL OF IMMUNOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started