Anti-Cancer Drug Screening with Microfluidic Technology

3D Bioprinting of Vascularized Tissues for in vitro and in vivo Applications

(2021) Earnest P. Chen et al.   Frontiers in Bioengineering and Biotechnology

Paper-based microfluidics: Simplified fabrication and assay methods

(2021) Sumaira Nishat et al.   SENSORS AND ACTUATORS B-CHEMICAL

Codependency of Metabolism and Epigenetics Drives Cancer Progression: A Review

(2020) Kenta Masui et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Liquid biopsy and tumor heterogeneity in metastatic solid tumors: the potentiality of blood samples

(2020) Marco Russano et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

A novel Wick‐Like Paper‐Based Microfluidic Device for 3D Cell Culture and Anti‐Cancer Drugs Screening

(2020) Shu‐xia Fu et al.   Biotechnology Journal

A microfluidic concentration gradient generator for simultaneous delivery of two reagents on a millimeter-sized sample

(2020) Milad Rismanian et al.   Journal of Flow Chemistry

3D bioprinting for reconstituting the cancer microenvironment

(2020) Pallab Datta et al.   npj Precision Oncology

Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids

(2020) Brooke Schuster et al.   Nature Communications

Low-dose anti-inflammatory combinatorial therapy reduced cancer stem cell formation in patient-derived preclinical models for tumour relapse prevention

(2019) Bee Luan Khoo et al.   BRITISH JOURNAL OF CANCER

On-Chip Anticancer Drug Screening – Recent Progress in Microfluidic Platforms to Address Challenges in Chemotherapy

(2019) Nandini Dhiman et al.   BIOSENSORS & BIOELECTRONICS

Simple, Cost-Effective, and Continuous 3D Dielectrophoretic Microchip for Concentration and Separation of Bioparticles

(2019) Parham Tajik et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Multilayer architecture microfluidic network array for combinatorial drug testing on 3D-cultured cells

(2019) Hao-Chen Chang et al.   Biofabrication

Cell-Based Assays on Microfluidics for Drug Screening

(2019) Xiaoyan Liu et al.   ACS Sensors

Could 3D models of cancer enhance drug screening?

(2019) Virginia Brancato et al.   BIOMATERIALS

A tool for designing tree-like concentration gradient generators for lab-on-a-chip applications

(2019) Milad Ebadi et al.   CHEMICAL ENGINEERING SCIENCE

Three-gradient constructions in a flow-rate insensitive microfluidic system for drug screening towards personalized treatment

(2019) Shaofei Shen et al.   TALANTA

A microfluidics platform for combinatorial drug screening on cancer biopsies

(2018) Federica Eduati et al.   Nature Communications

Improved microfluidic platform for simultaneous multiple drug screening towards personalized treatment

(2018) Oihane Mitxelena-Iribarren et al.   BIOSENSORS & BIOELECTRONICS

A multifunctional integrated simultaneously online screening microfluidic biochip for the examination of “efficacy-toxicity” and compatibility of medicine

(2018) Hechen Wang et al.   CHINESE CHEMICAL LETTERS

Scalable Multiplexed Drug-Combination Screening Platforms Using 3D Microtumor Model for Precision Medicine

(2018) Zhixiong Zhang et al.   Small

Drug screening of biopsy-derived spheroids using a self-generated microfluidic concentration gradient

(2018) Theresa Mulholland et al.   Scientific Reports

Cryoprotectant-Free Freezing of Cells Using Liquid Marbles Filled with Hydrogel

(2018) Raja Vadivelu et al.   ACS Applied Materials & Interfaces

A Plug-and-Play, Drug-on-Pillar Platform for Combination Drug Screening Implemented by Microfluidic Adaptive Printing

(2018) Jiannan Li et al.   ANALYTICAL CHEMISTRY

A new non-dimensional parameter to obtain the minimum mixing length in tree-like concentration gradient generators

(2018) Milad Rismanian et al.   CHEMICAL ENGINEERING SCIENCE

Expansion of patient-derived circulating tumor cells from liquid biopsies using a CTC microfluidic culture device

(2017) Bee Luan Khoo et al.   Nature Protocols

Numerical Simulation of the Behavior of Toroidal and Spheroidal Multicellular Aggregates in Microfluidic Devices with Microwell and U-Shaped Barrier

(2017) Maryam Barisam et al.   Micromachines

Drug screening of cancer cell lines and human primary tumors using droplet microfluidics

(2017) Ada Hang-Heng Wong et al.   Scientific Reports

Microfluidics for cell-based high throughput screening platforms—A review

(2016) Guansheng Du et al.   ANALYTICA CHIMICA ACTA

A concentration gradient generator on a paper-based microfluidic chip coupled with cell culture microarray for high-throughput drug screening

(2016) Bo Hong et al.   BIOMEDICAL MICRODEVICES

Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs

(2016) Vítor E. Santo et al.   Biotechnology Journal

Micro-dissected tumor tissues on chip: an ex vivo method for drug testing and personalized therapy

(2016) M. Astolfi et al.   LAB ON A CHIP

A microfluidic chip of multiple-channel array with various oxygen tensions for drug screening

(2016) Yaqiong Li et al.   Microfluidics and Nanofluidics

Engineering a Brain Cancer Chip for High-throughput Drug Screening

(2016) Yantao Fan et al.   Scientific Reports

Recent Progress of Microfluidics in Translational Applications

(2016) Zongbin Liu et al.   Advanced Healthcare Materials

Drug screening in 3D in vitro tumor models: overcoming current pitfalls of efficacy read-outs

(2016) Vítor E. Santo et al.   Biotechnology Journal

Liquid biopsy and therapeutic response: Circulating tumor cell cultures for evaluation of anticancer treatment

(2016) B. L. Khoo et al.   Science Advances

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

(2016) Michele Zanoni et al.   Scientific Reports

Drug cytotoxicity and signaling pathway analysis with three-dimensional tumor spheroids in a microwell-based microfluidic chip for drug screening

(2015) Yongli Chen et al.   ANALYTICA CHIMICA ACTA

Microfluidic-Enabled Print-to-Screen Platform for High-Throughput Screening of Combinatorial Chemotherapy

(2015) Yuzhe Ding et al.   ANALYTICAL CHEMISTRY

Monitoring Tumor Response to Anticancer Drugs Using Stable Three-Dimensional Culture in a Recyclable Microfluidic Platform

(2015) Wenming Liu et al.   ANALYTICAL CHEMISTRY

Slug flow heat transfer without phase change in microchannels: A review

(2015) Thilaksiri Bandara et al.   CHEMICAL ENGINEERING SCIENCE

Towards personalized medicine: chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform

(2015) Janine Ruppen et al.   LAB ON A CHIP

Prediction of human population responses to toxic compounds by a collaborative competition

(2015) Federica Eduati et al.   NATURE BIOTECHNOLOGY

Identification of drugs as single agents or in combination to prevent carcinoma dissemination in a microfluidic 3D environment

(2015) Jing Bai et al.   Oncotarget

A Novel 96well-formatted Micro-gap Plate Enabling Drug Response Profiling on Primary Tumour Samples

(2015) Wei-Yuan Ma et al.   Scientific Reports

Three Dimensional Microfluidic Cell Arrays for ex Vivo Drug Screening with Mimicked Vascular Flow

(2014) Zeynep Dereli-Korkut et al.   ANALYTICAL CHEMISTRY

Microfluidic System Based High Throughput Drug Screening System for Curcumin/TRAIL Combinational Chemotherapy in Human Prostate Cancer PC3 Cells

(2014) Dami An et al.   Biomolecules & Therapeutics

Parallel microfluidic chemosensitivity testing on individual slice cultures

(2014) Tim C. Chang et al.   LAB ON A CHIP

High-Throughput Screening (HTS) of Anticancer Drug Efficacy on a Micropillar/Microwell Chip Platform

(2013) Dong Woo Lee et al.   ANALYTICAL CHEMISTRY

Cancer heterogeneity: implications for targeted therapeutics

(2013) R Fisher et al.   BRITISH JOURNAL OF CANCER

A programmable microfluidic cell array for combinatorial drug screening

(2012) Jeongyun Kim et al.   LAB ON A CHIP

Combinatorial drug therapy for cancer in the post-genomic era

(2012) Bissan Al-Lazikani et al.   NATURE BIOTECHNOLOGY

Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery

(2011) Yuanpei Li et al.   BIOMATERIALS

An integrated microfluidic device for two-dimensional combinatorial dilution

(2011) Yun-Ho Jang et al.   LAB ON A CHIP

A radial microfluidic concentration gradient generator with high-density channels for cell apoptosis assay

(2011) Chun-Guang Yang et al.   LAB ON A CHIP

Impact of high-throughput screening in biomedical research

(2011) Ricardo Macarron et al.   NATURE REVIEWS DRUG DISCOVERY

Tumors on chips: oncology meets microfluidics

(2010) Donald Wlodkowic et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Droplet-based microfluidic system for multicellular tumor spheroid formation and anticancer drug testing

(2010) Linfen Yu et al.   LAB ON A CHIP

Microfluidic Single-Cell Array Cytometry for the Analysis of Tumor Apoptosis

(2009) Donald Wlodkowic et al.   ANALYTICAL CHEMISTRY

Microfluidic platform for controlling the differentiation of embryoid bodies

(2009) Wai-To Fung et al.   LAB ON A CHIP

Extracellular matrix dynamics in development and regenerative medicine

(2008) W. P. Daley et al.   JOURNAL OF CELL SCIENCE