Fusobacterium nucleatum Promotes Colorectal Cancer Cell to Acquire Stem Cell‐Like Features by Manipulating Lipid Droplet‐Mediated Numb Degradation

A nanotherapeutic strategy to overcome chemotherapeutic resistance of cancer stem-like cells

(2021) Shiyang Shen et al.   Nature Nanotechnology

Lipid droplets: platforms with multiple functions in cancer hallmarks

(2020) André L. S. Cruz et al.   Cell Death & Disease

NF-кB/HDAC1/SREBP1c pathway mediates the inflammation signal in progression of hepatic steatosis

(2020) Yunwei Guo et al.   Acta Pharmaceutica Sinica B

Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

(2020) Lisa M. Butler et al.   ADVANCED DRUG DELIVERY REVIEWS

Not So Slim Anymore—Evidence for the Role of SUMO in the Regulation of Lipid Metabolism

(2020) Amir Sapir   Biomolecules

Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data

(2019) Yang Hao et al.   BMC BIOINFORMATICS

Mitochondrial fusion regulates lipid homeostasis and stem cell maintenance in the Drosophila testis

(2019) Rafael Sênos Demarco et al.   NATURE CELL BIOLOGY

Fusobacterium nucleatum Facilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF-κB Signaling Pathways in Human Gingival Fibroblasts

(2019) Wenyan Kang et al.   Oxidative Medicine and Cellular Longevity

Concise review: Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells

(2019) Malini Visweswaran et al.   STEM CELLS

Fusobacterium nucleatum facilitates ulcerative colitis through activating IL‐17F signaling to NF‐κB via the upregulation of CARD3 expression

(2019) Yongyu Chen et al.   JOURNAL OF PATHOLOGY

CIDE family proteins control lipid homeostasis and the development of metabolic diseases

(2019) Feng‐Jung Chen et al.   TRAFFIC

JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance

(2018) Tianyi Wang et al.   Cell Metabolism

Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment

(2018) Lan Thi Hanh Phi et al.   Stem Cells International

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

(2017) Yongzhi Yang et al.   GASTROENTEROLOGY

Cancer stem cells in colorectal cancer: a review

(2017) Matthew J Munro et al.   JOURNAL OF CLINICAL PATHOLOGY

Analysis ofFusobacteriumpersistence and antibiotic response in colorectal cancer

(2017) Susan Bullman et al.   SCIENCE

Fatty acid synthase 2 contributes to diapause preparation in a beetle by regulating lipid accumulation and stress tolerance genes expression

(2017) Qian-Qian Tan et al.   Scientific Reports

Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice

(2016) Pengpeng Bi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

(2016) Keisuke Katsushima et al.   Nature Communications

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis

(2015) Chao Wang et al.   HEPATOLOGY

Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

(2015) Chamutal Gur et al.   IMMUNITY

The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids

(2015) Mirjana Kessler et al.   Nature Communications

MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells

(2014) Wei-Lun Hwang et al.   NATURE CELL BIOLOGY

Cancer stem cells in colorectal cancer from pathogenesis to therapy: Controversies and perspectives

(2014) Caterina Fanali   WORLD JOURNAL OF GASTROENTEROLOGY

Signal-peptide-mediated translocation is regulated by a p97–AIRAPL complex

(2013) Tal Glinka et al.   BIOCHEMICAL JOURNAL

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

A microRNA miR-34a-Regulated Bimodal Switch Targets Notch in Colon Cancer Stem Cells

(2013) Pengcheng Bu et al.   Cell Stem Cell

Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover

(2013) James A. Olzmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MDM2 Protein-mediated Ubiquitination of NUMB Protein

(2012) Matylda Sczaniecka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isolating lipid droplets from multiple species

(2012) Yunfeng Ding et al.   Nature Protocols

Differentiated Human Colorectal Cancer Cells Protect Tumor-Initiating Cells From Irinotecan

(2011) Benjamin L. Emmink et al.   GASTROENTEROLOGY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Notch signaling in stomach epithelial stem cell homeostasis

(2011) Tae-Hee Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer

(2010) S. S. Sikandar et al.   CANCER RESEARCH

Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets

(2010) Isamu Z. Hartman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

(2009) Ismael Samudio et al.   JOURNAL OF CLINICAL INVESTIGATION

Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma

(2009) Etienne Meylan et al.   NATURE

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

NUMB controls p53 tumour suppressor activity

(2008) Ivan N. Colaluca et al.   NATURE