Inflammation in Human Heart Failure: Major Mediators and Therapeutic Targets

Interleukin-6 and Outcomes in Acute Heart Failure: An ASCEND-HF Sub-Study

(2021) Antonio L. Perez et al.   JOURNAL OF CARDIAC FAILURE

Colchicine for Left Ventricular Infarct Size Reduction in Acute Myocardial Infarction: A Phase II, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Study Protocol – The COVERT-MI Study

(2021) Didier Bresson et al.   CARDIOLOGY

Methotrexate can prevent cardiovascular events in patients with rheumatoid arthritis

(2021) Kai-jun Sun et al.   MEDICINE

A pilot study evaluating GSK1070806 inhibition of interleukin-18 in renal transplant delayed graft function

(2021) E. Wlodek et al.   PLoS One

C-Reactive Protein Triggers Cell Death in Ischemic Cells

(2021) Ahmed Sheriff et al.   Frontiers in Immunology

From Systemic Inflammation to Myocardial Fibrosis

(2021) Walter J. Paulus et al.   CIRCULATION RESEARCH

Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: a randomized clinical trial

(2021) Steven G. Kelsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial

(2021) Paul M Ridker et al.   LANCET

High density lipoprotein cholesterol / C reactive protein ratio in heart failure with preserved ejection fraction

(2021) Masamichi Yano et al.   ESC Heart Failure

Effect of Colchicine in Reducing Inflammatory Biomarkers and Cardiovascular Risk in Coronary Artery Disease

(2021) Sujitha Sethuramalingam et al.   AMERICAN JOURNAL OF THERAPEUTICS

Immunoadsorption treatment for dilated cardiomyopathy

(2021) Ru-tao Bian et al.   MEDICINE

Interleukin 6 and Development of Heart Failure With Preserved Ejection Fraction in the General Population

(2021) Yook Chin Chia et al.   Journal of the American Heart Association

Heart Failure Syndrome With Preserved Ejection Fraction Is a Metabolic Cluster of Non-resolving Inflammation in Obesity

(2021) Bochra Tourki et al.   Frontiers in Cardiovascular Medicine

Prognostic value of sST2 in patients with heart failure with reduced, mid-range and preserved ejection fraction

(2020) Yu Song et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Reappraising the role of inflammation in heart failure

(2020) Luigi Adamo et al.   Nature Reviews Cardiology

Highlights in heart failure

(2020) Daniela Tomasoni et al.   ESC Heart Failure

Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease

(2020) Antonio Abbate et al.   CIRCULATION RESEARCH

Epidemiology, Pathophysiology and Contemporary Management of Cardiogenic Shock ‐ A position statement from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

(2020) Ovidiu Chioncel et al.   EUROPEAN JOURNAL OF HEART FAILURE

Inflammation in Heart Failure

(2020) Sean P. Murphy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Evaluation and management of heart failure with preserved ejection fraction

(2020) Barry A. Borlaug   Nature Reviews Cardiology

Colchicine for Secondary Cardiovascular Prevention: A Systematic Review

(2020) Carly A. Webb et al.   PHARMACOTHERAPY

Cardiogenic shock elicits acute inflammation, delayed eosinophilia, and depletion of immune cells in most severe cases

(2020) Justine Cuinet et al.   Scientific Reports

Effect of immunomodulation on cardiac remodelling and outcomes in heart failure: a quantitative synthesis of the literature

(2020) Navkaranbir S. Bajaj et al.   ESC Heart Failure

Early clinical experience with AZD4831, a novel myeloperoxidase inhibitor, developed for patients with heart failure with preserved ejection fraction

(2020) Karin Nelander et al.   CTS-Clinical and Translational Science

Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity

(2020) Bochra Tourki et al.   FASEB JOURNAL

Persistent congestion, renal dysfunction and inflammatory cytokines in acute heart failure: a prognosis study

(2020) Nicola R. Pugliese et al.   Journal of Cardiovascular Medicine

Circulating sST2 and catestatin levels in patients with acute worsening of heart failure: a report from the CATSTAT‐HF study

(2020) Josip A. Borovac et al.   ESC Heart Failure

Inflammatory Cytokines and Chemokines as Therapeutic Targets in Heart Failure

(2020) Anis Hanna et al.   CARDIOVASCULAR DRUGS AND THERAPY

Effect of Vericiguat vs Placebo on Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction

(2020) Paul W. Armstrong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

sST2 and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction

(2020) Rafael de la Espriella et al.   JOURNAL OF CARDIAC FAILURE

Myocarditis and inflammatory cardiomyopathy: current evidence and future directions

(2020) Carsten Tschöpe et al.   Nature Reviews Cardiology

What Is the Role of the Inflammation in the Pathogenesis of Heart Failure?

(2020) Elena C. Castillo et al.   Current Cardiology Reports

Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double‐blind, randomized, placebo‐controlled clinical trial

(2020) Mark R. Hazebroek et al.   EUROPEAN JOURNAL OF HEART FAILURE

Safety, tolerability, pharmacokinetics and effect on serum uric acid of the myeloperoxidase inhibitor AZD4831 in a randomized, placebo-controlled, phase 1 study in healthy volunteers

(2019) Li-Ming Gan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Anti-Inflammatory Therapy with Canakinumab for the Prevention of Hospitalization for Heart Failure

(2019) Brendan M. Everett et al.   CIRCULATION

Selective C‐reactive protein‐apheresis in patients

(2019) Wolfgang Ries et al.   THERAPEUTIC APHERESIS AND DIALYSIS

PentraSorb C‐Reactive Protein: Characterization of the Selective C‐Reactive Protein Adsorber Resin

(2019) Stephan Mattecka et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Myeloperoxidase – A bridge linking inflammation and oxidative stress with cardiovascular disease

(2019) Gjin Ndrepepa   CLINICA CHIMICA ACTA

Inducible nitric oxide synthase: Regulation, structure, and inhibition

(2019) Maris A. Cinelli et al.   MEDICINAL RESEARCH REVIEWS

The quest for anti‐inflammatory and immunomodulatory strategies in heart failure

(2019) Sophie Van Linthout et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Predicting Risk for Incident Heart Failure With Omega-3 Fatty Acids

(2019) Robert C. Block et al.   JACC-Heart Failure

Phase I trial of HuMax-IL8 (BMS-986253), an anti-IL-8 monoclonal antibody, in patients with metastatic or unresectable solid tumors

(2019) Marijo Bilusic et al.   Journal for ImmunoTherapy of Cancer

Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart Failure

(2019) Scott D. Solomon et al.   CIRCULATION

Various aspects of inflammation in heart failure

(2019) Mieczysław Dutka et al.   HEART FAILURE REVIEWS

The resolution of inflammation through omega-3 fatty acids in atherosclerosis, intimal hyperplasia, and vascular calcification

(2019) Miguel Carracedo et al.   Seminars in Immunopathology

Myeloperoxidase and the Risk of CKD Progression, Cardiovascular Disease, and Death in the Chronic Renal Insufficiency Cohort (CRIC) Study

(2019) Simon Correa et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Effect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure

(2019) Nikola Kozhuharov et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still’s disease

(2018) Cem Gabay et al.   ANNALS OF THE RHEUMATIC DISEASES

Conflicting vascular and metabolic impact of the IL-33/sST2 axis

(2018) Raffaele Altara et al.   CARDIOVASCULAR RESEARCH

Immune responsive resolvin D1 programs myocardial infarction–induced cardiorenal syndrome in heart failure

(2018) Ganesh V. Halade et al.   FASEB JOURNAL

Role of cytokines and inflammation in heart function during health and disease

(2018) Monika Bartekova et al.   HEART FAILURE REVIEWS

Effect of Interleukin-1 Blockade on Left Ventricular Systolic Performance and Work

(2018) Leo F. Buckley et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial

(2018) Paul M Ridker et al.   LANCET

Impact of tocilizumab on N-terminal pro-brain natriuretic peptide levels in patients with active rheumatoid arthritis without cardiac symptoms

(2018) I Yokoe et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Soluble ST2 in Heart Failure

(2018) Cian P. McCarthy et al.   Heart Failure Clinics

IL-1 Blockade in Patients With Heart Failure With Preserved Ejection Fraction

(2018) Benjamin W. Van Tassell et al.   Circulation-Heart Failure

Resolution of inflammation is altered in chronic heart failure and entails a dysfunctional responsiveness of T lymphocytes

(2018) Valerio Chiurchiù et al.   FASEB JOURNAL

IL-33 (Interleukin 33)/sST2 (Soluble Suppression of Tumorigenicity 2) Axis in Hypertension and Heart Failure

(2018) Rana Ghali et al.   HYPERTENSION

Chronic heart failure in adults: summary of updated NICE guidance

(2018) Jacqui Real et al.   BMJ-British Medical Journal

Levels of Proinflammatory Cytokines, Oxidative Stress, and Tissue Damage Markers in Patients with Acute Heart Failure with and without Cardiorenal Syndrome Type 1

(2018) Grazia Maria Virzì et al.   CardioRenal Medicine

Prolonged treatment with Tadekinig alfa in adult-onset Still’s disease

(2018) Uta Kiltz et al.   ANNALS OF THE RHEUMATIC DISEASES

Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction

(2018) Barry A. Borlaug et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

(2018) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

(2017) Veli-Pekka Harjola et al.   EUROPEAN JOURNAL OF HEART FAILURE

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-1 Receptor Blockade Rescues Myocarditis-Associated End-Stage Heart Failure

(2017) Giulio Cavalli et al.   Frontiers in Immunology

Heart Failure With Mid-Range (Borderline) Ejection Fraction

(2017) Jeffrey J. Hsu et al.   JACC-Heart Failure

Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing

(2017) Vasundhara Kain et al.   Scientific Reports

Effect of Omega-3 Acid Ethyl Esters on Left Ventricular Remodeling After Acute Myocardial InfarctionClinical Perspective

(2016) Bobak Heydari et al.   CIRCULATION

Resolving Inflammation in Heart Failure: Novel Protective Lipid Mediators

(2016) Marta Reina-Couto et al.   CURRENT DRUG TARGETS

Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial

(2016) Ola Kleveland et al.   EUROPEAN HEART JOURNAL

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

(2016) Piotr Ponikowski et al.   EUROPEAN JOURNAL OF HEART FAILURE

Interleukin-1 Blockade in Acute Decompensated Heart Failure

(2016) Benjamin W. Van Tassell et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus

(2016) Elizabeth A. McKie et al.   PLoS One

The emerging role of Toll-like receptor 4 in myocardial inflammation

(2016) Y Yang et al.   Cell Death & Disease

Estatinas e stresse oxidativo na insuficiência cardíaca crónica

(2016) Sónia Costa et al.   Revista Portuguesa de Cardiologia

Myeloperoxidase evokes substantial vasomotor responses in isolated skeletal muscle arterioles of the rat

(2015) V. Csató et al.   Acta Physiologica

Xanthine Oxidase Inhibitors in Heart Failure: Where Do We Go From Here?

(2015) L. Tamariz et al.   CIRCULATION

Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study

(2015) M. M. Givertz et al.   CIRCULATION

Innate Immunity and the Failing Heart

(2015) Douglas L. Mann   CIRCULATION RESEARCH

Acute heart failure and cardiogenic shock: a multidisciplinary practical guidance

(2015) A. Mebazaa et al.   INTENSIVE CARE MEDICINE

Hydralazine and nitrates alone or combined for the management of chronic heart failure: A systematic review

(2015) Mohamed Farag et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes

(2015) J. R. Thiele et al.   MEDIATORS OF INFLAMMATION

Pathophysiology and clinical evaluation of acute heart failure

(2015) Robert J. Mentz et al.   Nature Reviews Cardiology

Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction

(2015) Margaret M. Redfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

Myocardial pressure overload induces systemic inflammation through endothelial cell IL-33

(2015) Wei-Yu Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical implications of different biomarkers in elderly patients with heart failure

(2014) Irene Sanchez et al.   Biomarkers in Medicine

Pentoxifylline in Heart Failure: A Meta-Analysis of Clinical Trials

(2014) Sébastien Champion et al.   Cardiovascular Therapeutics

Wireless Pulmonary Artery Pressure Monitoring Guides Management to Reduce Decompensation in Heart Failure With Preserved Ejection Fraction

(2014) Philip B. Adamson et al.   Circulation-Heart Failure

Impaired resolution of inflammation in human chronic heart failure

(2014) Marta Reina-Couto et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Tocilizumab Treatment Increases Left Ventricular Ejection Fraction and Decreases Left Ventricular Mass Index in Patients with Rheumatoid Arthritis without Cardiac Symptoms: Assessed Using 3.0 Tesla Cardiac Magnetic Resonance Imaging

(2014) H. Kobayashi et al.   JOURNAL OF RHEUMATOLOGY

Inhibiting C-Reactive Protein for the Treatment of Cardiovascular Disease: Promising Evidence from Rodent Models

(2014) Alexander J. Szalai et al.   MEDIATORS OF INFLAMMATION

Unknown

(2014) Laura O’Brien et al.   MOLECULAR MEDICINE

Spironolactone for Heart Failure with Preserved Ejection Fraction

(2014) Bertram Pitt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting NOS as a therapeutic approach for heart failure

(2014) Lifei Tang et al.   PHARMACOLOGY & THERAPEUTICS

Circulating Levels of Tumor Necrosis Factor-Alpha Receptor 2 Are Increased in Heart Failure with Preserved Ejection Fraction Relative to Heart Failure with Reduced Ejection Fraction: Evidence for a Divergence in Pathophysiology

(2014) Brendan N. Putko et al.   PLoS One

Association of Interleukin 8 and Myocardial Recovery in Patients with ST-Elevation Myocardial Infarction Complicated by Acute Heart Failure

(2014) Trygve Husebye et al.   PLoS One

Anti-Inflammatory Treatment With Colchicine in Stable Chronic Heart Failure

(2014) Spyridon Deftereos et al.   JACC-Heart Failure

Effects of Interleukin-1 Blockade With Anakinra on Adverse Cardiac Remodeling and Heart Failure After Acute Myocardial Infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) Pilot Study]

(2013) Antonio Abbate et al.   AMERICAN JOURNAL OF CARDIOLOGY

Effects of Interleukin-1 Blockade With Anakinra on Aerobic Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction (from the D-HART Pilot Study)

(2013) Benjamin Wallace Van Tassell et al.   AMERICAN JOURNAL OF CARDIOLOGY

Serum biomarkers and clinical outcomes in heart failure patients treated de novo with carvedilol

(2013) Jadwiga Nessler et al.   Cardiology Journal

Is Tumor Necrosis Factor-α Friend or Foe for Chronic Heart Failure?

(2013) Masatsugu Hori et al.   CIRCULATION RESEARCH

Inflammatory cytokines in chronic heart failure: interleukin-8 is associated with adverse outcome. Results from CORONA

(2013) Ståle H. Nymo et al.   EUROPEAN JOURNAL OF HEART FAILURE

Role of inflammation in the pathogenesis of heart failure with preserved ejection fraction and its potential as a therapeutic target

(2013) N. Glezeva et al.   HEART FAILURE REVIEWS

Cardiac Outcome Prevention Effectiveness of Glucocorticoids in Acute Decompensated Heart Failure

(2013) Chao Liu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature

(2013) Svitlana Demyanets et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A Novel Paradigm for Heart Failure With Preserved Ejection Fraction

(2013) Walter J. Paulus et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Interleukin-18 and IL-18 Binding Protein

(2013) Charles A. Dinarello et al.   Frontiers in Immunology

Heart Failure

(2013) Eugene Braunwald   JACC-Heart Failure

Interleukin-33 Drives a Proinflammatory Endothelial Activation That Selectively Targets Nonquiescent Cells

(2012) Jürgen Pollheimer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inflammatory Cytokines in Heart Failure: Mediators and Markers

(2012) Lars Gullestad et al.   CARDIOLOGY

The pathophysiology of heart failure

(2012) Clinton D. Kemp et al.   CARDIOVASCULAR PATHOLOGY

Rehospitalization for Heart Failure

(2012) Akshay S. Desai et al.   CIRCULATION

Interleukin-10 Treatment Attenuates Pressure Overload–Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3–Dependent Inhibition of Nuclear Factor-κB

(2012) Suresh Kumar Verma et al.   CIRCULATION

Interleukin-6, -7, -8 and -10 predict outcome in acute myocardial infarction complicated by cardiogenic shock

(2012) Roland Prondzinsky et al.   Clinical Research in Cardiology

Intravenous immunoglobulin does not reduce left ventricular remodeling in patients with myocardial dysfunction during hospitalization after acute myocardial infarction

(2012) Lars Gullestad et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Changes in Uric Acid Levels and Allopurinol Use in Chronic Heart Failure: Association With Improved Survival

(2012) Israel Gotsman et al.   JOURNAL OF CARDIAC FAILURE

Altered serum levels of IL-33 in patients with advanced systolic chronic heart failure: correlation with oxidative stress

(2012) Hai-Feng Zhang et al.   Journal of Translational Medicine

Enhanced Interleukin-1 Activity Contributes to Exercise Intolerance in Patients with Systolic Heart Failure

(2012) Benjamin W. Van Tassell et al.   PLoS One

A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans

(2012) Nicholas R Jones et al.   Molecular Therapy-Nucleic Acids

Dose-dependent effects of omega-3-polyunsaturated fatty acids on systolic left ventricular function, endothelial function, and markers of inflammation in chronic heart failure of nonischemic origin

(2011) Deddo Moertl et al.   AMERICAN HEART JOURNAL

Usefulness of Soluble Concentrations of Interleukin Family Member ST2 as Predictor of Mortality in Patients With Acutely Decompensated Heart Failure Relative to Left Ventricular Ejection Fraction

(2011) Sergio Manzano-Fernández et al.   AMERICAN JOURNAL OF CARDIOLOGY

The glucocorticoid in acute decompensated heart failure: Dr Jekyll or Mr Hyde?

(2011) Francesco Massari et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Interleukin-33 Induces Expression of Adhesion Molecules and Inflammatory Activation in Human Endothelial Cells and in Human Atherosclerotic Plaques

(2011) Svitlana Demyanets et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IL-6/IL-6 receptor system and its role in physiological and pathological conditions

(2011) Masahiko Mihara et al.   CLINICAL SCIENCE

Systemic inflammation and cell activation reflects morbidity in chronic heart failure

(2011) Dani-Louise Dixon et al.   CYTOKINE

Interleukin 6 Underlies Angiotensin II–Induced Hypertension and Chronic Renal Damage

(2011) Weiru Zhang et al.   HYPERTENSION

Subacute Inflammatory Activation in Subjects with Acute Coronary Syndrome and Left Ventricular Dysfunction

(2011) Luisa De Gennaro et al.   INFLAMMATION

Akt Regulates IL-10 Mediated Suppression of TNFα-Induced Cardiomyocyte Apoptosis by Upregulating Stat3 Phosphorylation

(2011) Sanjiv Dhingra et al.   PLoS One

Resolvin E1 protects the rat heart against reperfusion injury

(2010) K. T. Keyes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Interleukin-6 stimulates epithelial sodium channels in mouse cortical collecting duct cells

(2010) Ke Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Higher C-Reactive Protein Predicts Worse Prognosis in Acute Heart Failure Only in Noninfected Patients

(2010) Patrícia Lourenço et al.   CLINICAL CARDIOLOGY

Use of Myeloperoxidase for Risk Stratification in Acute Heart Failure

(2010) T. Reichlin et al.   CLINICAL CHEMISTRY

Chronic Heart Failure: Contemporary Diagnosis and Management

(2010) Gautam V. Ramani et al.   MAYO CLINIC PROCEEDINGS

Interleukin-33, a Novel Member of the IL-1/IL-18 Cytokine Family, in Cardiology and Cardiac Surgery

(2010) P. Kunes et al.   THORACIC AND CARDIOVASCULAR SURGEON

TNF-α inhibition attenuates adverse myocardial remodeling in a rat model of volume overload

(2009) Lynetta J. Jobe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Myocardial inflammation and non-ischaemic heart failure: is there a role for C-reactive protein?

(2009) Oliver Zimmermann et al.   BASIC RESEARCH IN CARDIOLOGY

Interleukin-33 induces angiogenesis and vascular permeability through ST2/TRAF6-mediated endothelial nitric oxide production

(2009) Y.-S. Choi et al.   BLOOD

Interleukin 8 and cardiovascular disease

(2009) S. Apostolakis et al.   CARDIOVASCULAR RESEARCH

IL-10 attenuates TNF- -induced NF B pathway activation and cardiomyocyte apoptosis

(2009) S. Dhingra et al.   CARDIOVASCULAR RESEARCH

Divergent Tumor Necrosis Factor Receptor–Related Remodeling Responses in Heart Failure

(2009) Tariq Hamid et al.   CIRCULATION

Cytokines and acute heart failure

(2009) David Chen et al.   CRITICAL CARE MEDICINE

Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology

(2009) Stephane Heymans et al.   EUROPEAN JOURNAL OF HEART FAILURE

The Effects of METhotrexate Therapy on the Physical Capacity of Patients With ISchemic Heart Failure: A Randomized Double-Blind, Placebo-Controlled Trial (METIS Trial)

(2009) Daniel Medeiros Moreira et al.   JOURNAL OF CARDIAC FAILURE

Beta-Blockade With Nebivolol in Elderly Heart Failure Patients With Impaired and Preserved Left Ventricular Ejection Fraction

(2009) Dirk J. van Veldhuisen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Anti-Inflammatory Actions of Intravenous Immunoglobulin

(2008) Falk Nimmerjahn et al.   Annual Review of Immunology

IL-10 Inhibits Inflammation and Attenuates Left Ventricular Remodeling After Myocardial Infarction via Activation of STAT3 and Suppression of HuR

(2008) Prasanna Krishnamurthy et al.   CIRCULATION RESEARCH

Biology of TNFα and IL-10, and their imbalance in heart failure

(2008) Kuljeet Kaur et al.   HEART FAILURE REVIEWS

Prednisone Adding to Usual Care Treatment for Refractory Decompensated Congestive Heart Failure

(2008) Huimin Zhang et al.   International Heart Journal

Serial Sampling of ST2 Predicts 90-Day Mortality Following Destabilized Heart Failure

(2008) Saskia Boisot et al.   JOURNAL OF CARDIAC FAILURE

Activation of Inducible NOS in Peripheral Vessels and Outcomes in Heart Failure Patients

(2008) Yutaka Ishibashi et al.   JOURNAL OF CARDIAC FAILURE

Impact of Oxypurinol in Patients With Symptomatic Heart Failure

(2008) Joshua M. Hare et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

(2008) GISSI-HF investigators   LANCET

Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

(2008) GISSI-HF investigators   LANCET

The pathophysiology of acute heart failure—Is it all about fluid accumulation?

(2007) Gad Cotter et al.   AMERICAN HEART JOURNAL