Period 2 Regulates CYP2B10 Expression and Activity in Mouse Liver

Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1

(2021) Wenhao Ge et al.   Cell Death & Disease

Physicochemical Properties, Biotransformation, and Transport Pathways of Established and Newly Approved Medications: A Systematic Review of the Top 200 Most Prescribed Drugs vs. the FDA-Approved Drugs Between 2005 and 2016

(2019) Anitha Saravanakumar et al.   CLINICAL PHARMACOKINETICS

Cyp2b-null male mice are susceptible to diet-induced obesity and perturbations in lipid homeostasis

(2019) Melissa M Heintz et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of the CLOCK protein in liver detoxification

(2019) Mengjing Zhao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2

(2018) Mikyung Kim et al.   Biomolecules & Therapeutics

UDP-glucuronosyltransferases: Structure, Function and Drug Design Studies

(2018) Erica Candido Costa Mano et al.   CURRENT MEDICINAL CHEMISTRY

CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch

(2018) Rajesh Narasimamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacokinetics of Chinese medicines: strategies and perspectives

(2018) Ru Yan et al.   Chinese Medicine

The Clock Protein Bmal1 Regulates Circadian Expression and Activity of Sulfotransferase 1a1 in Mice

(2018) Lianxia Guo et al.   DRUG METABOLISM AND DISPOSITION

Cytochrome P450 Genetic Variations Can Predict mRNA Expression, Cyclophosphamide 4-Hydroxylation, and Treatment Outcomes in Chinese Patients With Non-Hodgkin's Lymphoma

(2017) Wenying Shu et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Period23′-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation

(2017) Seung-Hee Yoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis

(2016) Nicole M. Kettner et al.   CANCER CELL

Clock gene Per2 as a controller of liver carcinogenesis

(2016) Ali Mteyrek et al.   Oncotarget

The UDP-glucuronosyltransferases: Their role in drug metabolism and detoxification

(2013) Andrew Rowland et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

PER2 promotes glucose storage to liver glycogen during feeding and acute fasting by inducing Gys2 PTG and GL expression

(2013) Fabio Zani et al.   Molecular Metabolism

Role of the circadian clock gene Per2 in adaptation to cold temperature

(2013) Sylvie Chappuis et al.   Molecular Metabolism

Direct Regulation of CLOCK Expression by REV-ERB

(2011) Christine Crumbley et al.   PLoS One

Tissue Distribution and Gender-Divergent Expression of 78 Cytochrome P450 mRNAs in Mice

(2011) Helen J. Renaud et al.   TOXICOLOGICAL SCIENCES

TIME-DEPENDENT INHIBITORY EFFECT OF LIPOPOLYSACCHARIDE INJECTION ONPER1ANDPER2GENE EXPRESSION IN THE MOUSE HEART AND LIVER

(2010) Yusuke Yamamura et al.   CHRONOBIOLOGY INTERNATIONAL

Clock gene mPer2 functions in diurnal variation of acetaminophen induced hepatotoxicity in mice

(2010) Xiamusiya Kakan et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Substrate Specificity, Regulation, and Polymorphism of Human Cytochrome P450 2B6

(2009) Sui-Lin Mo et al.   CURRENT DRUG METABOLISM

Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK

(2008) Sonja Langmesser et al.   BMC MOLECULAR BIOLOGY

Molecular Characterization of CYP2B6 Substrates

(2008) Sean Ekins et al.   CURRENT DRUG METABOLISM

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

(2008) Andrew C. Liu et al.   PLoS Genetics