Curcumin is a Potential Adjuvant to Alleviates Diabetic Retinal Injury via Reducing Oxidative Stress and Maintaining Nrf2 Pathway Homeostasis

Curcumin analog A13 alleviates oxidative stress by activating Nrf2/ARE pathway and ameliorates fibrosis in the myocardium of high-fat-diet and streptozotocin-induced diabetic rats

(2020) Lanting Xiang et al.   Diabetology & Metabolic Syndrome

Curcumin, Alone or in Combination with Aminoguanidine, Increases Antioxidant Defenses and Glycation Product Detoxification in Streptozotocin-Diabetic Rats: A Therapeutic Strategy to Mitigate Glycoxidative Stress

(2020) Tayra Ferreira Oliveira Lima et al.   Oxidative Medicine and Cellular Longevity

Insulin: too much of a good thing is bad

(2020) Hubert Kolb et al.   BMC Medicine

Effects of Curcumin Supplementation on Blood Glucose, Insulin Resistance and Androgens in Patients with Polycystic Ovary Syndrome: A Randomized Double-Blind Placebo-Controlled Clinical Trial

(2020) Javad Heshmati et al.   PHYTOMEDICINE

Curcumin and/or omega-3 polyunsaturated fatty acids supplementation reduces insulin resistance and blood lipids in individuals with high risk of type 2 diabetes: a randomised controlled trial

(2019) Rohith N. Thota et al.   Lipids in Health and Disease

Curcumin, the golden spice in treating cardiovascular diseases

(2019) Hong Li et al.   BIOTECHNOLOGY ADVANCES

Ginsenoside Rb1 attenuates diabetic retinopathy in streptozotocin-induced diabetic rats

(2019) Changxia Dong et al.   Acta Cirurgica Brasileira

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

(2019) Natalia Robledinos-Antón et al.   Oxidative Medicine and Cellular Longevity

Curcumin Alleviates Diabetic Retinopathy in Experimental Diabetic Rats

(2018) Fang Yang et al.   OPHTHALMIC RESEARCH

Retinal Protection and Distribution of Curcumin in Vitro and in Vivo

(2018) Chiara B. M. Platania et al.   Frontiers in Pharmacology

Pathological Perturbations in Diabetic Retinopathy: Hyperglycemia, AGEs, Oxidative Stress and Inflammatory Pathways

(2018) Nikhil Shri Sahajpal et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Transcriptomics and single-cell RNA-sequencing

(2018) Daniel C. Chambers et al.   RESPIROLOGY

Investigating the Molecular Mechanism of Aqueous Extract of Cyclocarya paliurus on Ameliorating Diabetes by Transcriptome Profiling

(2018) Jing Li et al.   Frontiers in Pharmacology

Diabetic retinopathy: a complex pathophysiology requiring novel therapeutic strategies

(2018) Michael Whitehead et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Epigenetic regulation of redox signaling in diabetic retinopathy: Role of Nrf2

(2017) Renu A. Kowluru et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fenofibrate ameliorates diabetic retinopathy by modulating Nrf2 signaling and NLRP3 inflammasome activation

(2017) Qiuping Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The “Metabolic Memory” Theory and the Early Treatment of Hyperglycemia in Prevention of Diabetic Complications

(2017) Roberto Testa et al.   Nutrients

Nrf2 as molecular target for polyphenols: A novel therapeutic strategy in diabetic retinopathy

(2016) Seyed Fazel Nabavi et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Autophagy in Diabetic Retinopathy

(2016) Michelino Di Rosa et al.   Current Neuropharmacology

Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs

(2016) Varun Gulshan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Melanocortin receptor agonists MCR1-5protect photoreceptors from high-glucose damage and restore antioxidant enzymes in primary retinal cell culture

(2016) Rosa Maisto et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Diabetes mellitus statistics on prevalence and mortality: facts and fallacies

(2016) Paul Zimmet et al.   Nature Reviews Endocrinology

Resveratrol improves glycemic control in insulin-treated diabetic rats: participation of the hepatic territory

(2016) Caio Yogi Yonamine et al.   Nutrition & Metabolism

Implication of oxidative stress in progression of diabetic retinopathy

(2016) Tapan Behl et al.   SURVEY OF OPHTHALMOLOGY

Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

(2015) Betül Kocaadam et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Curcumin: A Natural Product for Diabetes and its Complications

(2015) Seyed Nabavi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Curcumin Attenuates Urinary Excretion of Albumin in Type II Diabetic Patients with Enhancing Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) System and Repressing Inflammatory Signaling Efficacies

(2015) H. Yang et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Update on Diabetes Classification

(2015) Celeste C. Thomas et al.   MEDICAL CLINICS OF NORTH AMERICA

Diabetic Retinopathy: Vascular and Inflammatory Disease

(2015) F. Semeraro et al.   Journal of Diabetes Research

Anthocyanins as a Potential Therapy for Diabetic Retinopathy

(2014) S.F. Nabavi et al.   CURRENT MEDICINAL CHEMISTRY

RNA sequencing identifies novel markers of non-small cell lung cancer

(2014) Seon-Sook Han et al.   LUNG CANCER

Mitochondria Damage in the Pathogenesis of Diabetic Retinopathy and in the Metabolic Memory Associated with its Continued Progression

(2013) Renu Kowluru   CURRENT MEDICINAL CHEMISTRY

NRF2 plays a protective role in diabetic retinopathy in mice

(2013) Zhenhua Xu et al.   DIABETOLOGIA

Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation

(2013) G. Vistoli et al.   FREE RADICAL RESEARCH

AGEs, rather than hyperglycemia, are responsible for microvascular complications in diabetes: A “glycoxidation-centric” point of view

(2013) N.C. Chilelli et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats

(2013) Susana González-Reyes et al.   Oxidative Medicine and Cellular Longevity

Diabetic retinopathy: pathogenesis, clinical grading, management and future developments

(2012) L. Z. Heng et al.   DIABETIC MEDICINE

Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis

(2012) Megan M. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS