Insights into the cytoprotective potential of Bergenia ligulata against oxalate-induced oxidative stress and epithelial–mesenchymal transition (EMT) via TGFβ1/p38MAPK pathway in human renal epithelial cells

Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway

(2021) Yujing Xia et al.   PPAR Research

Downregulation of inflammatory mediators by ethanolic extract of Bergenia ligulata (Wall.) in oxalate injured renal epithelial cells

(2021) Anubha Singh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Vitexin exerts protective effects against calcium oxalate crystal-induced kidney pyroptosis in vivo and in vitro

(2021) Tao Ding et al.   PHYTOMEDICINE

Kaempferol alleviates calcium oxalate crystal-induced renal injury and crystal deposition via regulation of the AR/NOX2 signaling pathway

(2021) Peng Yuan et al.   PHYTOMEDICINE

Inhibitors of Calcium Oxalate Crystallization for the Treatment of Oxalate Nephropathies

(2020) Anna Kletzmayr et al.   Advanced Science

Early Events in Actin Cytoskeleton Dynamics and E-Cadherin-Mediated Cell-Cell Adhesion during Epithelial-Mesenchymal Transition

(2020) Irina Y. Zhitnyak et al.   Cells

Hypoxia-induced epithelial to mesenchymal transition in cancer

(2020) Robert Y. Hapke et al.   CANCER LETTERS

Human kidney stone matrix proteins alleviate hyperoxaluria induced renal stress by targeting cell-crystal interactions

(2020) Shifa Narula et al.   LIFE SCIENCES

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

(2019) Loh et al.   Cells

Isolation of bioactive compounds from Bergenia ciliata (haw.) Sternb rhizome and their antioxidant and anticholinesterase activities

(2019) Roheena Zafar et al.   BMC Complementary and Alternative Medicine

Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment

(2018) Lin Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

The Role of Actin Dynamics and Actin-Binding Proteins Expression in Epithelial-to-Mesenchymal Transition and Its Association with Cancer Progression and Evaluation of Possible Therapeutic Targets

(2018) Magdalena Izdebska et al.   Biomed Research International

Peroxisome proliferator-activated receptor γ modulates renal crystal retention associated with high oxalate concentration by regulating tubular epithelial cellular transdifferentiation

(2018) Shujue Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Microvillar injury in renal tubular epithelial cells induced by calcium oxalate crystal and the protective role of epigallocatechin-3-gallate

(2017) Kedsarin Fong-ngern et al.   FASEB JOURNAL

NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells

(2017) Bruno R. B. Pires et al.   PLoS One

Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury

(2017) Marcia Bastos Convento et al.   Scientific Reports

Bergenin ameliorates diabetic nephropathy in rats via suppressing renal inflammation and TGF-β1-Smads pathway

(2016) Jing Yang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Genome-Wide Gene Expression Profiling of Randall’s Plaques in Calcium Oxalate Stone Formers

(2016) Kazumi Taguchi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Protective effect of epigallocatechin-3-gallate (EGCG) via Nrf2 pathway against oxalate-induced epithelial mesenchymal transition (EMT) of renal tubular cells

(2016) Rattiyaporn Kanlaya et al.   Scientific Reports

The most potent antilithiatic agent ameliorating renal dysfunction and oxidative stress from Bergenia ligulata rhizome

(2014) Deepika Aggarwal et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-nephrolithic potential of resveratrol via inhibition of ROS, MCP-1, hyaluronan and osteopontin in vitro and in vivo

(2014) Sang Hyuk Hong et al.   Pharmacological Reports

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

Association of Metabolic Syndrome Traits and Severity of Kidney Stones: Results From a Nationwide Survey on Urolithiasis in Japan

(2013) Yasuo Kohjimoto et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Aluminum Citrate Blocks Toxicity of Calcium Oxalate Crystals by Preventing Binding with Cell Membrane Phospholipids

(2013) Chungang Guo et al.   AMERICAN JOURNAL OF NEPHROLOGY

Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion

(2013) Hildegonda P.H. Naber et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exposure of Madin-Darby Canine Kidney (MDCK) Cells to Oxalate and Calcium Oxalate Crystals Activates Nicotinamide Adenine Dinucleotide Phosphate (NADPH)-Oxidase

(2013) Aslam Khan et al.   UROLOGY

Nephrolithiasis: Molecular Mechanism of Renal Stone Formation and the Critical Role Played by Modulators

(2013) Kanu Priya Aggarwal et al.   Biomed Research International

Anti-inflammatory effects of aromatic-turmerone through blocking of NF-κB, JNK, and p38 MAPK signaling pathways in amyloid β-stimulated microglia

(2012) Sun Young Park et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers

(2012) C Freudlsperger et al.   ONCOGENE

The epithelial–mesenchymal transition under control: Global programs to regulate epithelial plasticity

(2012) M. Angela Nieto et al.   SEMINARS IN CANCER BIOLOGY

The Role of the p38 MAPK Signaling Pathway in High Glucose-Induced Epithelial-Mesenchymal Transition of Cultured Human Renal Tubular Epithelial Cells

(2011) Zhi-Mei Lv et al.   PLoS One

Lefty antagonises TGF-β1 induced epithelial–mesenchymal transition in tubular epithelial cells

(2010) Mythily Mariasegaram et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NF- B-Dependent Plasticity of the Epithelial to Mesenchymal Transition Induced by Von Hippel-Lindau Inactivation in Renal Cell Carcinomas

(2010) A. J. Pantuck et al.   CANCER RESEARCH

First Prize (Tie): Oxidative Renal Cell Injury Induced by Calcium Oxalate Crystal and Renoprotection with Antioxidants: A Possible Role of Oxidative Stress in Nephrolithiasis

(2010) Mauricio Davalos et al.   JOURNAL OF ENDOUROLOGY

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

New Insights into Epithelial-Mesenchymal Transition in Kidney Fibrosis

(2009) Y. Liu   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The role of osteopontin in inflammatory processes

(2009) Susan Amanda Lund et al.   Journal of Cell Communication and Signaling

NF-κB activation in renal tubular epithelial cells by oxalate stimulation

(2008) Keiichi Tozawa et al.   INTERNATIONAL JOURNAL OF UROLOGY

The Acute and Long-Term Adverse Effects of Shock Wave Lithotripsy

(2008) James A. McAteer et al.   SEMINARS IN NEPHROLOGY

Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression

(2008) Laura Piccagli et al.   BMC STRUCTURAL BIOLOGY

Antioxidants and proteins in ethylene-treated kiwifruits

(2007) Yong-Seo Park et al.   FOOD CHEMISTRY