Kaempferol alleviates calcium oxalate crystal-induced renal injury and crystal deposition via regulation of the AR/NOX2 signaling pathway

Loss of the androgen receptor suppresses intrarenal calcium oxalate crystals deposition via altering macrophage recruitment/M2 polarization with change of the miR-185-5p/CSF-1 signals

(2019) Wei Zhu et al.   Cell Death & Disease

Structure and mechanisms of ROS generation by NADPH oxidases

(2019) Francesca Magnani et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice

(2018) Ming-Shiun Tsai et al.   TOXICOLOGY LETTERS

Kaempferol alleviates ox-LDL-induced apoptosis by up-regulation of miR-26a-5p via inhibiting TLR4/NF-κB pathway in human endothelial cells

(2018) Xiaoming Zhong et al.   BIOMEDICINE & PHARMACOTHERAPY

The molecular mechanisms of androgen receptor in nephrolithiasis

(2017) Ziyu Fang et al.   GENE

Enzymatic Synthesis of a Novel Kaempferol-3-O-β-d-glucopyranosyl-(1→4)-O-α-d-glucopyranoside Using Cyclodextrin Glucanotransferase and Its Inhibitory Effects on Aldose Reductase, Inflammation, and Oxidative Stress

(2017) Woo-Jae Choung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Renal Epithelial Cell Injury Induced by Calcium Oxalate Monohydrate Depends on Their Structural Features: Size, Surface, and Crystalline Structure

(2016) Xin-Yuan Sun et al.   Journal of Biomedical Nanotechnology

Genome-Wide Gene Expression Profiling of Randall’s Plaques in Calcium Oxalate Stone Formers

(2016) Kazumi Taguchi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Molecular modifiers reveal a mechanism of pathological crystal growth inhibition

(2016) Jihae Chung et al.   NATURE

Evaluation of protective effects of diosmin (a citrus flavonoid) in chemical-induced urolithiasis in experimental rats

(2016) V. Vinoth Prabhu et al.   PHARMACEUTICAL BIOLOGY

Systematic Review and Meta-analysis of the Clinical Effectiveness of Shock Wave Lithotripsy, Retrograde Intrarenal Surgery, and Percutaneous Nephrolithotomy for Lower-pole Renal Stones

(2015) James F. Donaldson et al.   EUROPEAN UROLOGY

Do kidney stone formers have a kidney disease?

(2015) Anna L. Zisman et al.   KIDNEY INTERNATIONAL

Nox family NADPH oxidases: Molecular mechanisms of activation

(2014) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Natural Promoters of Calcium Oxalate Monohydrate Crystallization

(2014) Sahar Farmanesh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Androgen Receptor Enhances Kidney Stone-CaOx Crystal Formation via Modulation of Oxalate Biosynthesis & Oxidative Stress

(2014) Liang Liang et al.   MOLECULAR ENDOCRINOLOGY

Androgens Involvement in the Pathogenesis of Renal Stones Formation

(2014) Mohammad Reza Naghii et al.   PLoS One

Specificity of Growth Inhibitors and their Cooperative Effects in Calcium Oxalate Monohydrate Crystallization

(2013) Sahar Farmanesh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NADPH Oxidases, Reactive Oxygen Species, and the Kidney: Friend and Foe

(2013) M. Sedeek et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Nephrolithiasis: Molecular Mechanism of Renal Stone Formation and the Critical Role Played by Modulators

(2013) Kanu Priya Aggarwal et al.   Biomed Research International

Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

(2012) Shrikant R. Mulay et al.   JOURNAL OF CLINICAL INVESTIGATION

Aluminum Citrate Prevents Renal Injury from Calcium Oxalate Crystal Deposition

(2012) L. M. Besenhofer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Testosterone and Androgen Receptor in Human Nephrolithiasis

(2010) Jin-Yi Li et al.   JOURNAL OF UROLOGY

Effect of Sex Hormones on Crystal Formation in a Stone-forming Rat Model

(2010) Iwao Yoshioka et al.   UROLOGY

Kaempferol is an estrogen-related receptor α and γ inverse agonist

(2009) Junjian Wang et al.   FEBS LETTERS