Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage

Modulating oxidant levels to promote healthy ageing

(2020) jose vina et al.   ANTIOXIDANTS & REDOX SIGNALING

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

(2020) Jonathan M. Ghergurovich et al.   Nature Chemical Biology

Plasma proteomic profile of frailty

(2020) Sanish Sathyan et al.   AGING CELL

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle : update 2019

(2019) Stephan Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

A Free Radical Theory of Frailty

(2018) Jose Viña et al.   FREE RADICAL BIOLOGY AND MEDICINE

Frailty Quantified by the “Valencia Score” as a Potential Predictor of Lifespan in Mice

(2018) Irene Martinez de Toda et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Starring or Supporting Role? Satellite Cells and Skeletal Muscle Fiber Size Regulation

(2018) Kevin A. Murach et al.   PHYSIOLOGY

Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator

(2018) Sunhee Hwang et al.   Nature Communications

Rapamycin improves healthspan but not inflammaging in nfκb1 −/− mice

(2018) Clara Correia-Melo et al.   AGING CELL

A New Frailty Score for Experimental Animals Based on the Clinical Phenotype: Inactivity as a Model of Frailty

(2017) Mari Carmen Gomez-Cabrera et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Short-term disuse promotes fatty acid infiltration into skeletal muscle

(2017) Allan F. Pagano et al.   Journal of Cachexia Sarcopenia and Muscle

A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse

(2017) Sathyaseelan S. Deepa et al.   GeroScience

A Multicomponent Exercise Intervention that Reverses Frailty and Improves Cognition, Emotion, and Social Networking in the Community-Dwelling Frail Elderly: A Randomized Clinical Trial

(2016) Francisco José Tarazona-Santabalbina et al.   Journal of the American Medical Directors Association

Biology of frailty: Modulation of ageing genes and its importance to prevent age-associated loss of function

(2016) Jose Viña et al.   MOLECULAR ASPECTS OF MEDICINE

Active paraplegics are protected against exercise-induced oxidative damage through the induction of antioxidant enzymes

(2016) M Inglés et al.   SPINAL CORD

G6PD protects from oxidative damage and improves healthspan in mice

(2016) Sandrina Nóbrega-Pereira et al.   Nature Communications

NADPH: new oxygen for the ROS theory of aging

(2016) Pablo J. Fernandez-Marcos et al.   Oncotarget

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan

(2015) Sebastian Brandhorst et al.   Cell Metabolism

Association between Oxidative Stress and Frailty in an Elderly German Population: Results from the ESTHER Cohort Study

(2015) Kai-Uwe Saum et al.   GERONTOLOGY

Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index

(2015) Alice E. Kane et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Reconsidering the Role of Mitochondria in Aging

(2015) Marta Gonzalez-Freire et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Oxidative Stress Is Related to Frailty, Not to Age or Sex, in a Geriatric Population: Lipid and Protein Oxidation as Biomarkers of Frailty

(2014) Marta Inglés et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

(2014) Diana Jurk et al.   Nature Communications

The slow-aging growth hormone receptor/binding protein gene-disrupted (GHR-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty

(2013) Oge Arum et al.   AGE

Growth Hormone Replacement Therapy Prevents Sarcopenia by a Dual Mechanism: Improvement of Protein Balance and of Antioxidant Defenses

(2013) T. Brioche et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Analysis of GSH and GSSG after derivatization with N-ethylmaleimide

(2013) Daniela Giustarini et al.   Nature Protocols

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

(2012) Anna-Maria Joseph et al.   AGING CELL

Age associated low mitochondrial biogenesis may be explained by lack of response of PGC-1α to exercise training

(2011) Frederic Derbré et al.   AGE

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

(2011) R. Sambasivan et al.   DEVELOPMENT

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

(2011) C. Lepper et al.   DEVELOPMENT

The Physical and Biological Characterization of a Frail Mouse Model

(2011) J. Walston et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The metabolic footprint of aging in mice

(2011) Riekelt H. Houtkooper et al.   Scientific Reports

Benfotiamine improves functional recovery of the infarcted heart via activation of pro-survival G6PD/Akt signaling pathway and modulation of neurohormonal response

(2010) Rajesh Katare et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets

(2009) Ilham Chelh et al.   BMC GENOMICS

Overexpression of Glucose-6-phosphate Dehydrogenase Extends the Life Span ofDrosophila melanogaster

(2008) Susan K. Legan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose-6-phosphate dehydrogenase deficiency

(2008) MD Cappellini et al.   LANCET