A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse

A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1−/ − mice is correlated to increased cellular senescence

(2017) Yiqiang Zhang et al.   Redox Biology

Frailty Syndrome is Associated with Altered Circulating Redox Balance and Increased Markers of Oxidative Stress

(2017) G. Serviddio et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Impaired mitochondrial degradation by autophagy in the skeletal muscle of the aged female interleukin 10 null mouse

(2016) Fred Ko et al.   EXPERIMENTAL GERONTOLOGY

Biomarkers of oxidative stress are associated with frailty: the Framingham Offspring Study

(2015) Christine K. Liu et al.   AGE

Sarcopenia as the Biological Substrate of Physical Frailty

(2015) Francesco Landi et al.   CLINICS IN GERIATRIC MEDICINE

Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index

(2015) Alice E. Kane et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype

(2015) Kavithalakshmi Sataranatarajan et al.   Redox Biology

The Frailty Syndrome: Clinical measurements and basic underpinnings in humans and animals

(2014) M. Jane Mohler et al.   EXPERIMENTAL GERONTOLOGY

Association of mitochondrial DNA levels with frailty and all-cause mortality

(2014) Foram N. Ashar et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Oxidative Stress Is Related to Frailty, Not to Age or Sex, in a Geriatric Population: Lipid and Protein Oxidation as Biomarkers of Frailty

(2014) Marta Inglés et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Skeletal muscle ATP kinetics are impaired in frail mice

(2013) Ashwin Akki et al.   AGE

CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice

(2013) Yiqiang Zhang et al.   FASEB JOURNAL

Dietary restriction attenuates the accelerated aging phenotype of Sod1−/− mice

(2013) Yiqiang Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinically Relevant Frailty Index for Mice

(2013) H. Liu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD

(2012) Young C. Jang et al.   AGING CELL

Low-grade chronic inflammation and superoxide anion production by NADPH oxidase are the main determinants of physical frailty in older adults

(2012) Gregory Baptista et al.   FREE RADICAL RESEARCH

Prevalence of Frailty in Community-Dwelling Older Persons: A Systematic Review

(2012) Rose M. Collard et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Oxidative Damage, Platelet Activation, and Inflammation to Predict Mobility Disability and Mortality in Older Persons: Results From the Health Aging and Body Composition Study

(2012) M. Cesari et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: Cross-sectional findings from the Newcastle 85+ Study

(2012) Joanna Collerton et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Inflammation and mortality in a frail mouse model

(2011) Fred Ko et al.   AGE

Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation

(2011) Lisa M. Larkin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

The Physical and Biological Characterization of a Frail Mouse Model

(2011) J. Walston et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase

(2010) Aphrodite Vasilaki et al.   AGING CELL

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

The Biology of Aging and Frailty

(2010) Neal S. Fedarko   CLINICS IN GERIATRIC MEDICINE

Spontaneous skin damage and delayed wound healing in SOD1-deficient mice

(2010) Yoshihito Iuchi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Is the oxidative stress theory of aging dead?

(2009) Viviana I. Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Upregulated monocytic expression of CXC chemokine ligand 10 (CXCL-10) and its relationship with serum interleukin-6 levels in the syndrome of frailty

(2009) Tao Qu et al.   CYTOKINE

Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration

(2009) Youngmok C. Jang et al.   FASEB JOURNAL

High Oxidative Stress Is Correlated with Frailty in Elderly Chinese

(2009) I-Chien Wu et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Molecular inflammation: Underpinnings of aging and age-related diseases

(2008) Hae Young Chung et al.   AGEING RESEARCH REVIEWS

Frailty in Older Mexican-American and European-American Adults: Is There an Ethnic Disparity?

(2008) Sara E. Espinoza et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY