m 6 A demethylase ALKBH5 drives denervation‐induced muscle atrophy by targeting HDAC4 to activate FoxO3 signalling

ALKBH5-mediated m6A demethylation of FOXM1 mRNA promotes progression of uveal melanoma

(2021) Lili Hao et al.   Aging-US

Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

(2021) Roberta Sartori et al.   Nature Communications

BMP2 Modified by the m6A Demethylation Enzyme ALKBH5 in the Ossification of the Ligamentum Flavum Through the AKT Signaling Pathway

(2020) Hai-Feng Wang et al.   CALCIFIED TISSUE INTERNATIONAL

RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

(2020) Chao Shen et al.   Cell Stem Cell

RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner

(2020) Xingya Guo et al.   Molecular Cancer

The potential role of RNA N6-methyladenosine in Cancer progression

(2020) Tianyi Wang et al.   Molecular Cancer

A single-cell transcriptomic landscape of primate arterial aging

(2020) Weiqi Zhang et al.   Nature Communications

The biological function of m6A demethylase ALKBH5 and its role in human disease

(2020) Jinyan Wang et al.   Cancer Cell International

Signaling Pathways That Control Muscle Mass

(2020) Anna Vainshtein et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ALKBH5 suppresses malignancy of hepatocellular carcinoma via m6A-guided epigenetic inhibition of LYPD1

(2020) Yunhao Chen et al.   Molecular Cancer

Roles of N6-Methyladenosine (m6A) in Stem Cell Fate Decisions and Early Embryonic Development in Mammals

(2020) Meng Zhang et al.   Frontiers in Cell and Developmental Biology

Cellular and molecular features of neurogenic skeletal muscle atrophy

(2020) Jeffrey T. Ehmsen et al.   EXPERIMENTAL NEUROLOGY

Skeletal Muscle Denervation Investigations: Selecting an Experimental Control Wisely

(2019) Haiming Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The N 6 -Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy

(2019) Lisa E. Dorn et al.   CIRCULATION

The Critical Role of RNA m6A Methylation in Cancer

(2019) Qing Lan et al.   CANCER RESEARCH

METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes

(2019) Huiwen Song et al.   Autophagy

Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

(2019) Hailing Shi et al.   MOLECULAR CELL

HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70

(2019) Liqing Luo et al.   Cell Reports

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle : update 2019

(2019) Stephan Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

HDAC4 regulates vascular inflammation via activation of autophagy

(2018) Di Yang et al.   CARDIOVASCULAR RESEARCH

Role of Forkhead Box O (FOXO) transcription factor in aging and diseases

(2018) Neelam Tia et al.   GENE

METTL3-mediated m6A modification is required for cerebellar development

(2018) Chen-Xin Wang et al.   PLOS BIOLOGY

Muscle Wasting Diseases: Novel Targets and Treatments

(2018) Regula Furrer et al.   Annual Review of Pharmacology and Toxicology

Refined RIP-seq protocol for epitranscriptome analysis with low input materials

(2018) Yong Zeng et al.   PLOS BIOLOGY

FoxO Transcription Factors are Critical Regulators of Diabetes-Related Muscle Atrophy

(2018) Brian T. O’Neill et al.   DIABETES

CARM1 contributes to skeletal muscle wasting by mediating FoxO3 activity and promoting myofiber autophagy

(2018) Yuantong Liu et al.   EXPERIMENTAL CELL RESEARCH

RNA-binding protein YTHDF3 suppresses interferon-dependent antiviral responses by promoting FOXO3 translation

(2018) Yuan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of myofiber-type-specific molecules using mass spectrometry imaging

(2018) Naoko Goto-Inoue et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells

(2017) Chong Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FTO is required for myogenesis by positively regulating mTOR-PGC-1α pathway-mediated mitochondria biogenesis

(2017) Xiaobo Wang et al.   Cell Death & Disease

The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation

(2017) Kensuke Kudou et al.   Open Biology

The role of E3 ubiquitin-ligases MuRF-1 and MAFbx in loss of skeletal muscle mass

(2016) Oren Rom et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA

(2016) Chuanzhao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy

(2015) Giulia Milan et al.   Nature Communications

SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia

(2014) Anne H.-H. Tseng et al.   BIOCHEMICAL JOURNAL

HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy

(2014) A. W. Beharry et al.   JOURNAL OF CELL SCIENCE

Posttranslational modifications control FoxO3 activity during denervation

(2011) Enrico Bertaggia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

(2010) Viviana Moresi et al.   CELL