Antibiotic Treatment, Mechanisms for Failure, and Adjunctive Therapies for Infections by Group A Streptococcus

Patterns of Antibiotic Nonsusceptibility Among Invasive Group A Streptococcus Infections—United States, 2006–2017

(2021) Katherine Fay et al.   CLINICAL INFECTIOUS DISEASES

Playing With Fire: Proinflammatory Virulence Mechanisms of Group A Streptococcus

(2021) Shyra Wilde et al.   Frontiers in Cellular and Infection Microbiology

Risk Factors and Predictors of Mortality in Streptococcal Necrotizing Soft-tissue Infections: A Multicenter Prospective Study

(2020) Trond Bruun et al.   CLINICAL INFECTIOUS DISEASES

Antibiotic degradation by commensal microbes shields pathogens

(2020) Mergim Gjonbalaj et al.   INFECTION AND IMMUNITY

Reduced in vitro susceptibility of Streptococcus pyogenes to beta-lactam antibiotics associated with mutations in the pbp2x gene is geographically widespread

(2020) James M. Musser et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A Single Amino Acid Replacement in Penicillin Binding Protein 2X in Streptococcus pyogenes Significantly Increases Fitness upon Subtherapeutic Benzylpenicillin Treatment in a Mouse Model of Necrotizing Myositis

(2020) Randall J. Olsen et al.   AMERICAN JOURNAL OF PATHOLOGY

Restricted Sequence Variation in Streptococcus pyogenes Penicillin Binding Proteins

(2020) Andrew Hayes et al.   mSphere

A role of epithelial cells and virulence factors in biofilm formation by Streptococcus pyogenes in vitro

(2020) Feiruz Alamiri et al.   INFECTION AND IMMUNITY

Group A Streptococcus Infection of the Nasopharynx Requires Proinflammatory Signaling Through the Interleukin-1 Receptor

(2020) Doris L. LaRock et al.   INFECTION AND IMMUNITY

Opportunistic Invasive Infection by Group A Streptococcus During Anti–Interleukin-6 Immunotherapy

(2020) Shyra Wilde et al.   JOURNAL OF INFECTIOUS DISEASES

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells

(2019) Jennifer M. Dan et al.   Science Translational Medicine

S2k guidelines for skin and soft tissue infections Excerpts from the S2k guidelines for “calculated initial parenteral treatment of bacterial infections in adults – update 2018“

(2019) Cord Sunderkötter et al.   JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT

Antibiotic penetration into bone and joints: An updated review

(2019) Abrar K. Thabit et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study

(2019) Nicola N Lynskey et al.   LANCET INFECTIOUS DISEASES

Streptococcus pyogenes with reduced susceptibility to β-lactams: how big an alarm bell?

(2019) William P Hanage et al.   CLINICAL INFECTIOUS DISEASES

Streptococcus pyogenes pbp2x Mutation Confers Reduced Susceptibility to β-lactam antibiotics

(2019) Kirsten Vannice et al.   CLINICAL INFECTIOUS DISEASES

Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis

(2018) Tom Parks et al.   CLINICAL INFECTIOUS DISEASES

Human polyspecific immunoglobulin attenuates group A streptococcal virulence factor activity and reduces disease severity in a murine necrotizing fasciitis model

(2018) Andrea (A) Tarnutzer et al.   CLINICAL MICROBIOLOGY AND INFECTION

Streptococcal pharyngitis and rheumatic heart disease: the superantigen hypothesis revisited

(2018) Jacklyn R. Hurst et al.   INFECTION GENETICS AND EVOLUTION

Streptococcus pneumoniae: transmission, colonization and invasion

(2018) Jeffrey N. Weiser et al.   NATURE REVIEWS MICROBIOLOGY

The Eagle Effect and Antibiotic-Induced Persistence: Two Sides of the Same Coin?

(2018) Anggia Prasetyoputri et al.   TRENDS IN MICROBIOLOGY

2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections

(2018) Massimo Sartelli et al.   World Journal of Emergency Surgery

Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial

(2017) Martin B. Madsen et al.   INTENSIVE CARE MEDICINE

Toxic shock syndrome – the seven Rs of management and treatment

(2017) Amanda L. Wilkins et al.   JOURNAL OF INFECTION

Toxin production of Clostridium difficile in sub-MIC of vancomycin and clindamycin alone and in combination with ceftazidime

(2017) Ebrahim Rezazadeh Zarandi et al.   MICROBIAL PATHOGENESIS

Necrotizing Soft-Tissue Infections

(2017) Dennis L. Stevens et al.   NEW ENGLAND JOURNAL OF MEDICINE

Macrolide and Clindamycin Resistance in Group a Streptococci Isolated From Children With Pharyngitis

(2017) Gregory P. DeMuri et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Adjunctive clindamycin for cellulitis: a clinical trial comparing flucloxacillin with or without clindamycin for the treatment of limb cellulitis

(2017) Richard Brindle et al.   BMJ Open

Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones

(2017) Simon Döhrmann et al.   Scientific Reports

Clindamycin Affects Group AStreptococcusVirulence Factors and Improves Clinical Outcome

(2016) Federica Andreoni et al.   JOURNAL OF INFECTIOUS DISEASES

Inflammatory properties of antibiotic-treated bacteria

(2016) Andrea J. Wolf et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Collective Resistance in Microbial Communities by Intracellular Antibiotic Deactivation

(2016) Robin A. Sorg et al.   PLOS BIOLOGY

Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing

(2015) Christopher N. LaRock et al.   Cell Host & Microbe

Management of necrotizing soft tissue infections in the intensive care unit: results of an international survey

(2015) Nicolas de Prost et al.   INTENSIVE CARE MEDICINE

Transfer of scarlet fever-associated elements into the group A Streptococcus M1T1 clone

(2015) Nouri L. Ben Zakour et al.   Scientific Reports

Clinical Efficacy of Polyspecific Intravenous Immunoglobulin Therapy in Patients With Streptococcal Toxic Shock Syndrome: A Comparative Observational Study

(2014) A. Linner et al.   CLINICAL INFECTIOUS DISEASES

Effectiveness of Clindamycin and Intravenous Immunoglobulin, and Risk of Disease in Contacts, in Invasive Group A Streptococcal Infections

(2014) J. R. Carapetis et al.   CLINICAL INFECTIOUS DISEASES

Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America

(2014) Dennis L. Stevens et al.   CLINICAL INFECTIOUS DISEASES

Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus

(2014) M. J. Walker et al.   CLINICAL MICROBIOLOGY REVIEWS

A Comprehensive Review on the Pharmacokinetics of Antibiotics in Interstitial Fluid Spaces in Humans: Implications on Dosing and Clinical Pharmacokinetic Monitoring

(2014) Tony K. L. Kiang et al.   CLINICAL PHARMACOKINETICS

Penicillin and Beta-Lactam Allergy: Epidemiology and Diagnosis

(2014) Eric Macy   CURRENT ALLERGY AND ASTHMA REPORTS

Streptococcus pyogenes Biofilm Growth In Vitro and In Vivo and Its Role in Colonization, Virulence, and Genetic Exchange

(2014) Laura R. Marks et al.   JOURNAL OF INFECTIOUS DISEASES

Emergence of scarlet fever Streptococcus pyogenes emm12 clones in Hong Kong is associated with toxin acquisition and multidrug resistance

(2014) Mark R Davies et al.   NATURE GENETICS

Failure of Clindamycin To Eradicate Infection with Beta-Hemolytic Streptococci Inducibly Resistant to Clindamycin in an Animal Model and in Human Infections

(2013) James S. Lewis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication

(2013) Timothy C. Barnett et al.   Cell Host & Microbe

Toxic Shock Syndrome

(2013) Donald E. Low   CRITICAL CARE CLINICS

Safely Diagnosing Clinically Significant Penicillin Allergy Using Only Penicilloyl-Poly-Lysine, Penicillin, and Oral Amoxicillin

(2013) Eric Macy et al.   Journal of Allergy and Clinical Immunology-In Practice

Detection of group A Streptococcus in tonsils from pediatric patients reveals high rate of asymptomatic streptococcal carriage

(2012) Amity L Roberts et al.   BMC Pediatrics

Intracellular Streptococcus pyogenes in Human Macrophages Display an Altered Gene Expression Profile

(2012) Erika Hertzén et al.   PLoS One

In vitroandin vivoproperties differ among liquid intravenous immunoglobulin preparations

(2012) F. Dhainaut et al.   VOX SANGUINIS

Epidemiological characterization of Streptococcus pyogenes isolated from patients with multiple onsets of pharyngitis

(2011) Taiji Ogawa et al.   FEMS MICROBIOLOGY LETTERS

Prevalence of Streptococcal Pharyngitis and Streptococcal Carriage in Children: A Meta-analysis

(2010) N. Shaikh et al.   PEDIATRICS

Molecular Pathogenesis of Necrotizing Fasciitis

(2009) Randall J. Olsen et al.   Annual Review of Pathology-Mechanisms of Disease

The role of beta-lactamase-producing-bacteria in mixed infections

(2009) Itzhak Brook   BMC INFECTIOUS DISEASES

Relationship between Expression of the Family of M Proteins and Lipoteichoic Acid to Hydrophobicity and Biofilm Formation in Streptococcus pyogenes

(2009) Harry S. Courtney et al.   PLoS One

Epidemiology of Severe Streptococcus pyogenes Disease in Europe

(2008) T. L. Lamagni et al.   JOURNAL OF CLINICAL MICROBIOLOGY