IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay

lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCFβ-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer

(2020) Qingzhu Yang et al.   Molecular Therapy-Nucleic Acids

Toll-like Receptors and the Control of Immunity

(2020) Katherine A. Fitzgerald et al.   CELL

Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells

(2020) Chun-Jie Guo et al.   CELL

Proteomics Using Protease Alternatives to Trypsin Benefits from Sequential Digestion with Trypsin

(2020) Therese Dau et al.   ANALYTICAL CHEMISTRY

NF-κB activation is a turn on for vaccinia virus phosphoprotein A49 to turn off NF-κB activation

(2019) Sarah Neidel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response

(2019) Hiroki Tanaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The PSIPRED Protein Analysis Workbench: 20 years on

(2019) Daniel W A Buchan et al.   NUCLEIC ACIDS RESEARCH

Translation-dependent unwinding of stem–loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs

(2019) Takashi Mino et al.   NUCLEIC ACIDS RESEARCH

Large-scale Discovery of Substrates of the Human Kinome

(2019) Naoyuki Sugiyama et al.   Scientific Reports

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis

(2019) Nobuyuki Kakiuchi et al.   NATURE

Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy

(2019) Jun Wei et al.   NATURE

Somatic inflammatory gene mutations in human ulcerative colitis epithelium

(2019) Kosaku Nanki et al.   NATURE

RNA-binding proteins control gene expression and cell fate in the immune system

(2018) Martin Turner et al.   NATURE IMMUNOLOGY

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

(2018) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions

(2018) KL Pennington et al.   ONCOGENE

14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface

(2018) Tobias Karlberg et al.   Nature Communications

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions

(2016) Mariko Yokogawa et al.   Scientific Reports

Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms

(2015) Takashi Mino et al.   CELL

LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins

(2014) Darui Xu et al.   BIOINFORMATICS

EVM005: An Ectromelia-Encoded Protein with Dual Roles in NF-κB Inhibition and Virulence

(2014) Nicholas van Buuren et al.   PLoS Pathogens

Malt1-Induced Cleavage of Regnase-1 in CD4+ Helper T Cells Regulates Immune Activation

(2013) Takuya Uehata et al.   CELL

How cells get the message: dynamic assembly and function of mRNA–protein complexes

(2013) Michaela Müller-McNicoll et al.   NATURE REVIEWS GENETICS

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Human Interleukin-1 Receptor-associated Kinase-2 Is Essential for Toll-like Receptor-mediated Transcriptional and Post-transcriptional Regulation of Tumor Necrosis Factor α

(2011) Sinead M. Flannery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR–IL-1R by controlling degradation of regnase-1

(2011) Hidenori Iwasaki et al.   NATURE IMMUNOLOGY

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

(2011) Kristen L. Meerbrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

The Pioneer Round of Translation: Features and Functions

(2010) Lynne E. Maquat et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Large-Scale Comparative Phosphoproteomics Identifies Conserved Phosphorylation Sites in Plants

(2010) H. Nakagami et al.   PLANT PHYSIOLOGY

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Interleukin-1 Receptor-associated Kinase 2 Is Critical for Lipopolysaccharide-mediated Post-transcriptional Control

(2009) Youzhong Wan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

(2009) Kazufumi Matsushita et al.   NATURE

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

(2009) Shengli Hao et al.   NATURE IMMUNOLOGY

Interleukin 1α-induced NFκB Activation and Chemokine mRNA Stabilization Diverge at IRAK1

(2008) Justin Hartupee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IRAK1: A critical signaling mediator of innate immunity

(2007) Sridevi Gottipati et al.   CELLULAR SIGNALLING