Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

Ventromedial hypothalamic nucleus neuronal subset regulates blood glucose independently of insulin

(2020) Jonathan N. Flak et al.   JOURNAL OF CLINICAL INVESTIGATION

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high fat diet

(2020) Joely A. Kellard et al.   Molecular Metabolism

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

(2019) Elisa Vergari et al.   Nature Communications

Glucose controls glucagon secretion by directly modulating cAMP in alpha cells

(2019) Qian Yu et al.   DIABETOLOGIA

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

(2018) Rayner Rodriguez-Diaz et al.   Cell Metabolism

Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+Mobilization From Acidic Stores in Pancreatic α-Cells

(2018) Alexander Hamilton et al.   DIABETES

α-cell glucokinase suppresses glucose-regulated glucagon secretion

(2018) Davide Basco et al.   Nature Communications

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets

(2018) Linford J.B. Briant et al.   Cell Reports

Somatostatin is Only Partly Required for the Glucagonostatic Effect of Glucose but is Necessary for the Glucagonostatic Effect of KATPChannel Blockers

(2018) Bao-Khanh Lai et al.   DIABETES

Insulin Secretion Depends on Intra-islet Glucagon Signaling

(2018) Berit Svendsen et al.   Cell Reports

Release and Decay Kinetics of Copeptin vs AVP in Response to Osmotic Alterations in Healthy Volunteers

(2017) Wiebke K Fenske et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

δ-cells and β-cells are electrically coupled and regulate α-cell activity via somatostatin

(2017) L. J. B. Briant et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Central Catecholaminergic Circuit Controls Blood Glucose Levels during Stress

(2017) Zhe Zhao et al.   NEURON

Bidirectional Anticipation of Future Osmotic Challenges by Vasopressin Neurons

(2017) Yael Mandelblat-Cerf et al.   NEURON

Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts

(2017) Nathan Lawlor et al.   Scientific Reports

Copeptin in the diagnosis of vasopressin-dependent disorders of fluid homeostasis

(2016) Mirjam Christ-Crain et al.   Nature Reviews Endocrinology

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

Functional identification of a neurocircuit regulating blood glucose

(2016) Thomas H. Meek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

(2016) Michael R. DiGruccio et al.   Molecular Metabolism

Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets

(2015) David M. Blodgett et al.   DIABETES

Evaluation of Efficacy and Safety of the Glucagon Receptor Antagonist LY2409021 in Patients With Type 2 Diabetes: 12- and 24-Week Phase 2 Studies

(2015) Christof M. Kazda et al.   DIABETES CARE

A Parabrachial-Hypothalamic Cholecystokinin Neurocircuit Controls Counterregulatory Responses to Hypoglycemia

(2014) Alastair S. Garfield et al.   Cell Metabolism

Hypoglycemia-Activated GLUT2 Neurons of the Nucleus Tractus Solitarius Stimulate Vagal Activity and Glucagon Secretion

(2014) Christophe M. Lamy et al.   Cell Metabolism

Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes

(2014) Mikkel Christensen et al.   DIABETES

Neural regulation of pancreatic islet cell mass and function

(2014) B. Thorens   DIABETES OBESITY & METABOLISM

ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion

(2014) Patrik Rorsman et al.   DIABETOLOGIA

Comparison Between Copeptin and Vasopressin in a Population From the Community and in People With Chronic Kidney Disease

(2014) Ronan Roussel et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Neural pathways that control the glucose counterregulatory response

(2014) Anthony J. M. Verberne et al.   Frontiers in Neuroscience

AVP neurons in the paraventricular nucleus of the hypothalamus regulate feeding

(2014) Hongjuan Pei et al.   Molecular Metabolism

C1 neurons: the body's EMTs

(2013) Patrice G. Guyenet et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Glucose Control of Glucagon Secretion: There Is More to It Than KATP Channels

(2013) E. Gylfe   DIABETES

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome

(2013) A. C. Nica et al.   GENOME RESEARCH

Cooperation between brain and islet in glucose homeostasis and diabetes

(2013) Michael W. Schwartz et al.   NATURE

Concentrations of the Stress Hormone Copeptin Increase upon Hypoglycaemia in Patients with Type 1 Diabetes Dependent of Hypoglycaemia Awareness

(2013) Eleonora Seelig et al.   PLoS One

Early Loss of the Glucagon Response to Hypoglycemia in Adolescents With Type 1 Diabetes

(2012) A. Siafarikas et al.   DIABETES CARE

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

(2012) Roger H. Unger et al.   JOURNAL OF CLINICAL INVESTIGATION

Glucose-Dependent Insulinotropic Polypeptide: A Bifunctional Glucose-Dependent Regulator of Glucagon and Insulin Secretion in Humans

(2011) M. Christensen et al.   DIABETES

Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?

(2011) J. N. Walker et al.   DIABETES OBESITY & METABOLISM

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

(2010) Yang Z. De Marinis et al.   Cell Metabolism

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

Central mechanisms of osmosensation and systemic osmoregulation

(2008) Charles W. Bourque   NATURE REVIEWS NEUROSCIENCE

Copeptin: clinical use of a new biomarker

(2008) Nils G. Morgenthaler et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM