Differential Molecular Responses of Zebrafish Larvae to Fluoxetine and Norfluoxetine

Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study

(2021) Nicolas Hoertel et al.   MOLECULAR PSYCHIATRY

The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue

(2021) Melissa Zimniak et al.   Scientific Reports

Developmental Neurotoxicity of Environmentally Relevant Pharmaceuticals and Mixtures Thereof in a Zebrafish Embryo Behavioural Test

(2021) Alessandro Atzei et al.   International Journal of Environmental Research and Public Health

Combination Therapy with Fluoxetine and the Nucleoside Analog GS-441524 Exerts Synergistic Antiviral Effects against Different SARS-CoV-2 Variants In Vitro

(2021) Linda Brunotte et al.   Pharmaceutics

Transcriptional analyses reveal different mechanism of toxicity for a chronic exposure to fluoxetine and venlafaxine on the brain of the marine fish Dicentrarchrus labrax

(2021) Carolina Costa et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

(2021) Damian F Santomauro et al.   LANCET

Proximate causes and ultimate effects of common antidepressants, fluoxetine and venlafaxine, on fish behavior

(2021) Arash Salahinejad et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Norfluoxetine Is the Only Metabolite of Fluoxetine in Zebrafish (Danio rerio) Embryos That Accumulates at Environmentally Relevant Exposure Scenarios

(2020) Florian Zindler et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Comparative transcriptomics implicate mitochondrial and neurodevelopmental impairments in larval zebrafish (Danio rerio) exposed to two selective serotonin reuptake inhibitors (SSRIs)

(2020) Irvin J. Huang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Do environmentally relevant concentrations of fluoxetine and citalopram impair stress-related behavior in zebrafish (Danio rerio) embryos?

(2020) Florian Zindler et al.   CHEMOSPHERE

Assessment of multiclass pharmaceutical active compounds (PhACs) in hospital WWTP influent and effluent samples by UHPLC-Orbitrap MS: Temporal variation, removals and environmental risk assessment

(2020) Christina I. Kosma et al.   ENVIRONMENTAL RESEARCH

Norfluoxetine and venlafaxine in zebrafish larvae: Single and combined toxicity of two pharmaceutical products relevant for risk assessment

(2020) P. Rodrigues et al.   JOURNAL OF HAZARDOUS MATERIALS

New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio)

(2020) Tingting Chai et al.   ENVIRONMENTAL POLLUTION

Developmental fluoxetine exposure in zebrafish reduces offspring basal cortisol concentration via life stage-dependent maternal transmission

(2019) Rubén Martinez et al.   PLoS One

Varying the exposure period and duration of neuroactive pharmaceuticals and their metabolites modulates effects on the visual motor response in zebrafish (Danio rerio) larvae

(2019) Irvin J. Huang et al.   NEUROTOXICOLOGY AND TERATOLOGY

Comparison of the accumulation and metabolite of fluoxetine in zebrafish larva under different environmental conditions with or without carbon nanotubes

(2019) Zhenhua Yan et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Environmental concentration of fluoxetine disturbs larvae behavior and increases the defense response at molecular level in zebrafish (Danio rerio)

(2019) Marco Parolini et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Antibiotics and antidepressants occurrence in surface waters and sediments collected in the north of Portugal

(2019) Maria João Fernandes et al.   CHEMOSPHERE

Tissue bioconcentration and effects of fluoxetine in zebrafish ( Danio rerio ) and red crucian cap ( Carassius auratus ) after short-term and long-term exposure

(2018) Chenyuan Pan et al.   CHEMOSPHERE

Fluoxetine modulates the transcription of genes involved in serotonin, dopamine and adrenergic signalling in zebrafish embryos

(2018) V. Cunha et al.   CHEMOSPHERE

Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR

(2018) Christopher Manzella et al.   Scientific Reports

Transgenerational hypocortisolism and behavioral disruption are induced by the antidepressant fluoxetine in male zebrafish Danio rerio

(2018) Marilyn N. Vera-Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bioaccumulation Behavior of Pharmaceuticals and Personal Care Products in Adult Zebrafish (Danio rerio): Influence of Physical-Chemical Properties and Biotransformation

(2017) Fangfang Chen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Enantioselective transformation of fluoxetine in water and its ecotoxicological relevance

(2017) María Jesús Andrés-Costa et al.   Scientific Reports

Population-relevant endpoints in the evaluation of endocrine-active substances (EAS) for ecotoxicological hazard and risk assessment

(2017) Mary S Marty et al.   Integrated Environmental Assessment and Management

Danio rerio embryos on Prozac ⿿ Effects on the detoxification mechanism and embryo development

(2016) V. Cunha et al.   AQUATIC TOXICOLOGY

Development of a modified acetonitrile-based extraction procedure followed by ultra-high performance liquid chromatography–tandem mass spectrometry for the analysis of psychiatric drugs in sediments

(2016) Lúcia H.M.L.M. Santos et al.   JOURNAL OF CHROMATOGRAPHY A

Sertraline accumulation and effects in the estuarine decapod Carcinus maenas : Importance of the history of exposure to chemical stress

(2015) Aurélie P. Rodrigues et al.   JOURNAL OF HAZARDOUS MATERIALS

Zebrafish models of major depressive disorders

(2015) Trehani M. Fonseka et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Occurrence and removal of transformation products of PPCPs and illicit drugs in wastewaters: A review

(2015) Eleni N. Evgenidou et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Joint effects of salinity and the antidepressant sertraline on the estuarine decapod Carcinus maenas

(2014) Aurélie P. Rodrigues et al.   AQUATIC TOXICOLOGY

Growth inhibition and coordinated physiological regulation of zebrafish (Danio rerio) embryos upon sublethal exposure to antidepressant amitriptyline

(2014) Ming Yang et al.   AQUATIC TOXICOLOGY

Fluoxetine effects on sheepshead minnow (Cyprinodon variegatus) locomotor activity

(2014) Virginia L. Winder et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES

Similar anxiolytic effects of agonists targeting serotonin 5-HT1A or cannabinoid CB receptors on zebrafish behavior in novel environments

(2013) Kristin A. Connors et al.   AQUATIC TOXICOLOGY

Enantioselective quantification of fluoxetine and norfluoxetine by HPLC in wastewater effluents

(2013) Ana R. Ribeiro et al.   CHEMOSPHERE

Normalization strategies for gene expression studies by real-time PCR in a marine fish species, Scophthalmus maximus

(2013) R. Urbatzka et al.   Marine Genomics

Global gene expression in larval zebrafish (Danio rerio) exposed to selective serotonin reuptake inhibitors (fluoxetine and sertraline) reveals unique expression profiles and potential biomarkers of exposure

(2012) June-Woo Park et al.   ENVIRONMENTAL POLLUTION

α- and β-Adrenoceptors of zebrafish in melanosome movement: A comparative study between embryo and adult melanophores

(2011) Jian Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gene expression analysis of ABC efflux transporters, CYP1A and GSTα in Nile tilapia after exposure to benzo(a)pyrene

(2011) Joana Costa et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Multi-residue determination of the sorption of illicit drugs and pharmaceuticals to wastewater suspended particulate matter using pressurised liquid extraction, solid phase extraction and liquid chromatography coupled with tandem mass spectrometry

(2011) David R. Baker et al.   JOURNAL OF CHROMATOGRAPHY A

Pharmaceuticals as Neuroendocrine Disruptors: Lessons Learned from Fish on Prozac

(2011) Jan A. Mennigen et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Adverse effects of serotonin depletion in developing zebrafish

(2011) Mark J. Airhart et al.   NEUROTOXICOLOGY AND TERATOLOGY

PHARMACEUTICAL METABOLITES IN THE ENVIRONMENT: ANALYTICAL CHALLENGES AND ECOLOGICAL RISKS

(2009) Mary D. Celiz et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Genetic dissection of dopaminergic and noradrenergic contributions to catecholaminergic tracts in early larval zebrafish

(2009) Edda Kastenhuber et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Pharmacokinetics and pharmacodynamics of norfluoxetine in rats: Increasing extracellular serotonin level in the frontal cortex

(2009) Ying Qu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Norfluoxetine Induces Spawning and Parturition in Estuarine and Freshwater Bivalves

(2008) P. P. Fong et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Physiological Endpoints for Potential SSRI Interactions in Fish

(2008) N. Kreke et al.   CRITICAL REVIEWS IN TOXICOLOGY