New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio)

Norfluoxetine Is the Only Metabolite of Fluoxetine in Zebrafish (Danio rerio) Embryos That Accumulates at Environmentally Relevant Exposure Scenarios

(2020) Florian Zindler et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

GPR 30 reduces myocardial infarct area and fibrosis in female ovariectomized mice by activating the PI3K/AKT pathway

(2019) Xiaowu Wang et al.   LIFE SCIENCES

Exposure to low-level metalaxyl impacts the cardiac development and function of zebrafish embryos

(2019) Yuqiong Wu et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Global scanning of selective serotonin reuptake inhibitors: occurrence, wastewater treatment and hazards in aquatic systems

(2019) Rachel A. Mole et al.   ENVIRONMENTAL POLLUTION

Acute exposure of zebrafish (Danio rerio) larvae to environmental concentrations of selected antidepressants: Bioaccumulation, physiological and histological changes

(2019) Karolina Nowakowska et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Toxicity assessment of pyriproxyfen in vertebrate model zebrafish embryos ( Danio rerio ): A multi biomarker study

(2018) Kannan Maharajan et al.   AQUATIC TOXICOLOGY

Comparison of emerging contaminants in receiving waters downstream of a conventional wastewater treatment plant and a forest-water reuse system

(2018) Andrew D. McEachran et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity

(2018) Zain Z. Zakaria et al.   Biomed Research International

Macrolides induce severe cardiotoxicity and developmental toxicity in zebrafish embryos

(2018) Zhaoyang Yan et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The psychoactive pollutant fluoxetine compromises antipredator behaviour in fish

(2017) Jake M. Martin et al.   ENVIRONMENTAL POLLUTION

Chronic fluoxetine treatment enhances sympathetic activities associated with abnormality of baroreflex function in conscious normal rats

(2017) Ling-Zong Hong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Discovery of Small Molecules Targeting the Synergy of Cardiac Transcription Factors GATA4 and NKX2-5

(2017) Mika J. Välimäki et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of some pharmaceuticals in municipal wastewater of Almadinah Almunawarah

(2017) Amjad Shraim et al.   Arabian Journal of Chemistry

A Developmental Toxicology Assay Platform for Screening Teratogenic Liability of Pharmaceutical Compounds

(2016) Karen Augustine-Rauch et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

The Biological Basis for Cardiac Repair After Myocardial Infarction

(2016) Sumanth D. Prabhu et al.   CIRCULATION RESEARCH

Cardiac Fibrosis

(2016) Joshua G. Travers et al.   CIRCULATION RESEARCH

Inflammatory and fibrotic responses of cardiac fibroblasts to myocardial damage associated molecular patterns (DAMPs)

(2016) Neil A. Turner   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Regulation of Coronary Blood Flow During Exercise in Failing Heart

(2016) Xin Xu et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Characterization of pharmaceutically active compounds in Dongting Lake, China: Occurrence, chiral profiling and environmental risk

(2016) Ruixue Ma et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Physiological, pharmacological and toxicological considerations of drug-induced structural cardiac injury

(2015) M J Cross et al.   BRITISH JOURNAL OF PHARMACOLOGY

New insights into the acute actions from a high dosage of fluoxetine on neuronal and cardiac function: Drosophila, crayfish and rodent models

(2015) Zana R. Majeed et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Aquatic toxicology of fluoxetine: Understanding the knowns and the unknowns

(2014) Adam Michael Stewart et al.   AQUATIC TOXICOLOGY

Enantiomer-Specific In Vitro Biotransformation of Select Pharmaceuticals in Rainbow Trout (Oncorhynchus mykiss)

(2013) Kristin A. Connors et al.   CHIRALITY

Nkx genes are essential for maintenance of ventricular identity

(2013) K. L. Targoff et al.   DEVELOPMENT

Evaluation of acute and developmental effects of difenoconazole via multiple stage zebrafish assays

(2013) Xiyan Mu et al.   ENVIRONMENTAL POLLUTION

Simultaneous stereoselective detection of chiral fungicides in soil by LC-MS/MS with fast sample preparation

(2013) Tingting Chai et al.   JOURNAL OF SEPARATION SCIENCE

Antidepressants Cause Bradycardia and Heart Block in GD 13 Rat Embryos In Vitro

(2012) Deena Ababneh et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Trace analysis of fluoxetine and its metabolite norfluoxetine. Part II: Enantioselective quantification and studies of matrix effects in raw and treated wastewater by solid phase extraction and liquid chromatography–tandem mass spectrometry

(2012) Victoria K.H. Barclay et al.   JOURNAL OF CHROMATOGRAPHY A

Anti-depressants make amphipods see the light

(2010) Yasmin Guler et al.   AQUATIC TOXICOLOGY

Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish

(2010) Jared V Goldstone et al.   BMC GENOMICS

Pharmacologically active compounds in the environment and their chirality

(2010) Barbara Kasprzyk-Hordern   CHEMICAL SOCIETY REVIEWS

Analyzing habituation responses to novelty in zebrafish (Danio rerio)

(2009) Keith Wong et al.   BEHAVIOURAL BRAIN RESEARCH

Fish on prozac: Effect of serotonin reuptake inhibitors on cognition in goldfish.

(2008) Alfred Beulig et al.   BEHAVIORAL NEUROSCIENCE

Uptake and depuration of the anti-depressant fluoxetine by the Japanese medaka (Oryzias latipes)

(2008) Gordon Paterson et al.   CHEMOSPHERE

Use of toxicity assays for enantiomeric discrimination of pharmaceutical substances

(2008) Fernando De Andrés et al.   CHIRALITY

The effects of pH on fluoxetine in Japanese medaka (Oryzias latipes): Acute toxicity in fish larvae and bioaccumulation in juvenile fish

(2007) Yuki Nakamura et al.   CHEMOSPHERE