Impaired Cognitive Function and Hippocampal Changes Following Chronic Diazepam Treatment in Middle-Aged Mice

Benzodiazepine exposure induces transcriptional down-regulation of GABAA receptor α1 subunit gene via L-type voltage-gated calcium channel activation in rat cerebrocortical neurons

(2020) María Florencia Foitzick et al.   NEUROSCIENCE LETTERS

The long-term but not short-term use of benzodiazepine impairs motoric function and upregulates amyloid β in part through the suppression of translocator protein

(2020) Marianna E. Jung et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Exercise adaptations: molecular mechanisms and potential targets for therapeutic benefit

(2020) Sean L. McGee et al.   Nature Reviews Endocrinology

Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain

(2020) Alana M. Horowitz et al.   SCIENCE

Dendritic Spines: Mediators of Cognitive Resilience in Aging and Alzheimer’s Disease

(2020) Courtney K. Walker et al.   NEUROSCIENTIST

Is the Long-Term Use of Benzodiazepines Associated With Worse Cognition Performance in Highly Educated Older Adults?

(2020) Linzi Liu et al.   Frontiers in Psychiatry

Exercise Prevents Memory Consolidation Defects Via Enhancing Prolactin Responsiveness of CA1 Neurons in Mice Under Chronic Stress

(2019) Yea-Hyun Leem et al.   MOLECULAR NEUROBIOLOGY

Repetitive transcranial magnetic stimulation ameliorates recognition memory impairment induced by hindlimb unloading in mice associated with BDNF/TrkB signaling

(2019) Baohui Zhai et al.   NEUROSCIENCE RESEARCH

Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking

(2019) Joshua M. Lorenz-Guertin et al.   Frontiers in Cellular Neuroscience

Long-Term Moderate Exercise Rescues Age-Related Decline in Hippocampal Neuronal Complexity and Memory

(2018) Sheng-Feng Tsai et al.   GERONTOLOGY

NMDA Receptor Subunits Change after Synaptic Plasticity Induction and Learning and Memory Acquisition

(2018) María Verónica Baez et al.   NEURAL PLASTICITY

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

Short-term treatment with flumazenil restores long-term object memory in a mouse model of Down syndrome

(2017) Damien Colas et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Aging Impairs Hippocampal- Dependent Recognition Memory and LTP and Prevents the Associated RyR Up-regulation

(2017) Alejandra Arias-Cavieres et al.   Frontiers in Aging Neuroscience

Drebrin A regulates hippocampal LTP and hippocampus-dependent fear learning in adult mice

(2016) N. Kojima et al.   NEUROSCIENCE

Chronic benzodiazepine treatment decreases spine density in cortical pyramidal neurons

(2016) Yasmina Curto et al.   NEUROSCIENCE LETTERS

Morphologic changes of dendritic spines of striatal neurons in the levodopa-induced dyskinesia model

(2014) Haruo Nishijima et al.   MOVEMENT DISORDERS

Benzodiazepines and risk of Alzheimer's disease

(2014) K. Yaffe et al.   BMJ-British Medical Journal

Diazepam treatment blocks the elevation of hippocampal activity and the accelerated proliferation of hippocampal neural stem cells after focal cerebral ischemia in mice

(2013) Rokuya Nochi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

(2013) William A. Toy et al.   NEUROBIOLOGY OF DISEASE

Age-dependent kinetics of dentate gyrus neurogenesis in the absence of cyclin D2

(2012) Anne Ansorg et al.   BMC NEUROSCIENCE

Impact of contextual cues in the expression of the memory associated with diazepam withdrawal: involvement of hippocampal PKMζin vivo, and Arc expression and LTPin vitro

(2012) Maria C. Monti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Benzodiazepine-induced spatial learning deficits in rats are regulated by the degree of modulation of α1 GABAA receptors

(2012) Srđan Joksimović et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities

(2012) Ana M M Oliveira et al.   NATURE NEUROSCIENCE

GABAA Receptor α Subunits Differentially Contribute to Diazepam Tolerance after Chronic Treatment

(2012) Christiaan H. Vinkers et al.   PLoS One

Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging

(2011) J. Eric Ahlskog et al.   MAYO CLINIC PROCEEDINGS

Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation

(2011) M. Mucha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

(2011) Kelley Bromley-Brits et al.   Jove-Journal of Visualized Experiments

Early exercise promotes positive hippocampal plasticity and improves spatial memory in the adult life of rats

(2010) Sérgio Gomes da Silva et al.   HIPPOCAMPUS

Co-Treatment with Diazepam Prevents the Effects of Fluoxetine on the Proliferation and Survival of Hippocampal Dentate Granule Cells

(2009) Xuefei Wu et al.   BIOLOGICAL PSYCHIATRY

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Neurod1 is essential for the survival and maturation of adult-born neurons

(2009) Zhengliang Gao et al.   NATURE NEUROSCIENCE

Diazepam neuroprotection in excitotoxic and oxidative stress involves a mitochondrial mechanism additional to the GABAAR and hypothermic effects

(2009) Anna Sarnowska et al.   NEUROCHEMISTRY INTERNATIONAL

Forced, moderate-intensity treadmill exercise suppresses apoptosis by increasing the level of NGF and stimulating phosphatidylinositol 3-kinase signaling in the hippocampus of induced aging rats

(2009) Chang-Hun Chae et al.   NEUROCHEMISTRY INTERNATIONAL

Changes in hippocampal arc protein expression and synaptic plasticity by the presentation of contextual cues linked to drug experience

(2009) María Carolina Monti et al.   SYNAPSE

Neurogenesis and Exercise: Past and Future Directions

(2008) Henriette van Praag   NEUROMOLECULAR MEDICINE

Chronic benzodiazepine treatment of cells expressing recombinant GABAA receptors uncouples allosteric binding: studies on possible mechanisms

(2003) Noore J. Ali et al.   JOURNAL OF NEUROCHEMISTRY