SARS-CoV-2 variants of concern display enhanced intrinsic pathogenic properties and expanded organ tropism in mouse models

Prospective Longitudinal Serosurvey of Health Care Workers in the First Wave of the SARS-CoV-2 Pandemic in a Quaternary Care Hospital in Munich, Germany

(2021) Tobias Weinberger et al.   CLINICAL INFECTIOUS DISEASES

Evolution of antibody immunity to SARS-CoV-2

(2021) Christian Gaebler et al.   NATURE

K18-hACE2 mice develop respiratory disease resembling severe COVID-19

(2021) Claude Kwe Yinda et al.   PLoS Pathogens

Cytokines and Chemokines in SARS-CoV-2 Infections—Therapeutic Strategies Targeting Cytokine Storm

(2021) Alexandra Pum et al.   Biomolecules

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

(2021) Wilfredo F. Garcia-Beltran et al.   CELL

SARS-CoV-2 induces human plasmacytoid predendritic cell diversification via UNC93B and IRAK4

(2021) Fanny Onodi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SARS-CoV-2 spike D614G change enhances replication and transmission

(2021) Bin Zhou et al.   NATURE

SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO

(2021) Jing Wu et al.   Cell Reports

Increased sCD163 and sCD14 Plasmatic Levels and Depletion of Peripheral Blood Pro-Inflammatory Monocytes, Myeloid and Plasmacytoid Dendritic Cells in Patients With Severe COVID-19 Pneumonia

(2021) Maria Antonella Zingaropoli et al.   Frontiers in Immunology

SARS-CoV-2 Causes a Different Cytokine Response Compared to Other Cytokine Storm-Causing Respiratory Viruses in Severely Ill Patients

(2021) Marton Olbei et al.   Frontiers in Immunology

SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates

(2021) Nikolaos C. Kyriakidis et al.   npj Vaccines

Emerging SARS-CoV-2 Variants and Impact in Global Vaccination Programs against SARS-CoV-2/COVID-19

(2021) Carmen Elena Gómez et al.   Vaccines

The role of autophagy in controlling SARS‐CoV‐2 infection: An overview on virophagy‐mediated molecular drug targets

(2021) Saman Sargazi et al.   CELL BIOLOGY INTERNATIONAL

Novel SARS-CoV-2 variants: the pandemics within the pandemic

(2021) Erik Boehm et al.   CLINICAL MICROBIOLOGY AND INFECTION

Innate immune sensing of coronavirus and viral evasion strategies

(2021) Yusuke Kasuga et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

SARS-CoV-2 one year on: evidence for ongoing viral adaptation

(2021) Thomas P. Peacock et al.   JOURNAL OF GENERAL VIROLOGY

Functional landscape of SARS-CoV-2 cellular restriction

(2021) Laura Martin-Sancho et al.   MOLECULAR CELL

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

(2021) Benjamin Krämer et al.   IMMUNITY

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species

(2021) Ruoke Wang et al.   IMMUNITY

SARS-CoV-2 variants, spike mutations and immune escape

(2021) William T. Harvey et al.   NATURE REVIEWS MICROBIOLOGY

Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants

(2021) Yongfei Cai et al.   SCIENCE

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

(2020) Bette Korber et al.   CELL

Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020

(2020) Maximilian Muenchhoff et al.   Eurosurveillance

A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

(2020) Kenneth H. Dinnon et al.   NATURE

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function

(2020) Emma S. Winkler et al.   NATURE IMMUNOLOGY

ACE2 mouse models: a toolbox for cardiovascular and pulmonary research

(2020) Hongpeng Jia et al.   Nature Communications

Evasion of Type I Interferon by SARS-CoV-2

(2020) Hongjie Xia et al.   Cell Reports

Covid-19: Perspectives on Innate Immune Evasion

(2020) Nima Taefehshokr et al.   Frontiers in Immunology

Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

(2020) Joseph W. Golden et al.   JCI Insight

Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice

(2020) Fatai S. Oladunni et al.   Nature Communications

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

(2020) Steffen Klein et al.   Nature Communications

SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication

(2020) Soren Alexandersen et al.   Nature Communications

Sources of Type I Interferons in Infectious Immunity: Plasmacytoid Dendritic Cells Not Always in the Driver's Seat

(2019) Shafaqat Ali et al.   Frontiers in Immunology

Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4

(2015) Kun Li et al.   JOURNAL OF INFECTIOUS DISEASES

IFN-  Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1  and LFA-1

(2011) N. Hagberg et al.   JOURNAL OF IMMUNOLOGY

Severe and Persistent Depletion of Circulating Plasmacytoid Dendritic Cells in Patients with 2009 Pandemic H1N1 Infection

(2011) Miriam Lichtner et al.   PLoS One