SARS-CoV-2 induces human plasmacytoid predendritic cell diversification via UNC93B and IRAK4

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

An Updated Systematic Review of the Therapeutic Role of Hydroxychloroquine in Coronavirus Disease-19 (COVID-19)

(2020) Saibal Das et al.   CLINICAL DRUG INVESTIGATION

The hallmarks of COVID-19 disease

(2020) Daolin Tang et al.   PLoS Pathogens

Presence of Genetic Variants Among Young Men With Severe COVID-19

(2020) Caspar I. van der Made et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells

(2020) Cesar A. Corzo et al.   Science Signaling

COVID-19: Emergence, Spread, Possible Treatments, and Global Burden

(2020) Raghuvir Keni et al.   Frontiers in Public Health

COVID-19: discovery, diagnostics and drug development

(2020) Tarik Asselah et al.   JOURNAL OF HEPATOLOGY

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

(2020) Qian Zhang et al.   SCIENCE

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

(2020) Paul Bastard et al.   SCIENCE

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Type I Interferon in Chronic Virus Infection and Cancer

(2017) Laura M. Snell et al.   TRENDS IN IMMUNOLOGY

High Secretion of Interferons by Human Plasmacytoid Dendritic Cells upon Recognition of Middle East Respiratory Syndrome Coronavirus

(2015) Vivian A. Scheuplein et al.   JOURNAL OF VIROLOGY

Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

(2015) M. J. Ciancanelli et al.   SCIENCE

Differential Responses of Plasmacytoid Dendritic Cells to Influenza Virus and Distinct Viral Pathogens

(2014) J. M. Thomas et al.   JOURNAL OF VIROLOGY

Trafficking of endosomal Toll-like receptors

(2014) Bettina L. Lee et al.   TRENDS IN CELL BIOLOGY

Toll-Like Receptors’ Pathway Disturbances are Associated with Increased Susceptibility to Infections in Humans

(2013) Josias Brito Frazão et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Adenosine Deaminase Acts as a Natural Antagonist for Dipeptidyl Peptidase 4-Mediated Entry of the Middle East Respiratory Syndrome Coronavirus

(2013) V. S. Raj et al.   JOURNAL OF VIROLOGY

Negative Regulation of Type I IFN Expression by OASL1 Permits Chronic Viral Infection and CD8+ T-Cell Exhaustion

(2013) Myeong Sup Lee et al.   PLoS Pathogens

HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells

(2012) J. Florentin et al.   BLOOD

HIV-1, interferon and the interferon regulatory factor system: An interplay between induction, antiviral responses and viral evasion

(2012) Giulia Marsili et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Plasmacytoid dendritic cells control T-cell response to chronic viral infection

(2012) L. Cervantes-Barragan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus

(2012) Karim Sacre et al.   ARTHRITIS RESEARCH & THERAPY

Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics

(2011) Jean-Laurent Casanova et al.   Annual Review of Immunology

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

(2011) Yiqi Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid predendritic cells (pDCs)

(2010) Y. Lepelletier et al.   BLOOD

Impaired Toll-like receptor 7 and 9 signaling: from chronic viral infections to cancer

(2010) Ivan Hirsch et al.   TRENDS IN IMMUNOLOGY

Irreversible Loss of pDCs by Apoptosis During Early HIV Infection May Be a Critical Determinant of Immune Dysfunction

(2010) Singh Meera et al.   VIRAL IMMUNOLOGY