PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
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Title
PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
Authors
Keywords
PARP1, PARylation, PARG, oligodendrocytes (OLs), oligodendrocyte progenitor cells (OPCs), myelination, remyelination, demyelination, multiple sclerosis, OPC differentiation
Journal
Cell Reports
Volume 37, Issue 1, Pages 109695
Publisher
Elsevier BV
Online
2021-10-06
DOI
10.1016/j.celrep.2021.109695
References
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Note: Only part of the references are listed.- The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling
- (2021) Sheng Zhang et al. JOURNAL OF NEUROSCIENCE
- Activated microglia drive demyelination via CSF1R signaling
- (2021) Dave E. Marzan et al. GLIA
- White Matter Alterations in Fmr1 Knockout Mice during Early Postnatal Brain Development
- (2020) Da Shi et al. DEVELOPMENTAL NEUROSCIENCE
- Conditional depletion of Fus in oligodendrocytes leads to motor hyperactivity and increased myelin deposition associated with Akt and cholesterol activation
- (2020) Kelly M. Guzman et al. GLIA
- Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα–mediated lipid metabolism
- (2020) Xin Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways
- (2020) Sheng Zhang et al. Nature Communications
- Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury
- (2020) Manideep Chavali et al. NEURON
- HIFα Regulates Developmental Myelination Independent of Autocrine Wnt Signaling
- (2020) Sheng Zhang et al. JOURNAL OF NEUROSCIENCE
- The role of nuclear receptors in the differentiation of oligodendrocyte precursor cells derived from fetal and adult neural stem cells
- (2019) Vito Antonio Baldassarro et al. Stem Cell Research
- Novel insights into PARPs in gene expression: regulation of RNA metabolism
- (2019) Yueshuang Ke et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination
- (2019) Huan Xu et al. NEURON
- The Enigmatic Function of PARP1: From PARylation Activity to PAR Readers
- (2019) Tatiana Kamaletdinova et al. Cells
- Proteomic Analysis of the Downstream Signaling Network of PARP1
- (2018) Yuanli Zhen et al. BIOCHEMISTRY
- Sox2 Is Essential for Oligodendroglial Proliferation and Differentiation during Postnatal Brain Myelination and CNS Remyelination
- (2018) Sheng Zhang et al. JOURNAL OF NEUROSCIENCE
- The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord
- (2018) Sheng Zhang et al. MOLECULAR NEUROBIOLOGY
- Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia
- (2018) Fei Wang et al. NEURON
- PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes
- (2017) Rebecca Gupte et al. GENES & DEVELOPMENT
- RNA-binding Protein Quaking StabilizesSirt2mRNA during Oligodendroglial Differentiation
- (2017) Merlin P. Thangaraj et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PARP-1 Controls the Adipogenic Transcriptional Program by PARylating C/EBPβ and Modulating Its Transcriptional Activity
- (2017) Xin Luo et al. MOLECULAR CELL
- lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1 /Suz12 Complex in the CNS
- (2017) Danyang He et al. NEURON
- PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: Effect on cell survival and differentiation
- (2017) Vito A. Baldassarro et al. Stem Cell Research
- First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib
- (2016) Dominic I. James et al. ACS Chemical Biology
- Thyroid Hormone Signaling in Oligodendrocytes: from Extracellular Transport to Intracellular Signal
- (2016) Jae Young Lee et al. MOLECULAR NEUROBIOLOGY
- Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system
- (2016) S. Marques et al. SCIENCE
- Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation
- (2016) Chuntao Zhao et al. Nature Communications
- Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage
- (2016) Sarah Moyon et al. Cell Reports
- Involvement of MeCP2 in Regulation of Myelin-Related Gene Expression in Cultured Rat Oligodendrocytes
- (2015) Kedarlal Sharma et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- The Wnt Effector Transcription Factor 7-Like 2 Positively Regulates Oligodendrocyte Differentiation in a Manner Independent of Wnt/ -Catenin Signaling
- (2015) E. Hammond et al. JOURNAL OF NEUROSCIENCE
- Protective actions of PJ34, a poly(ADP-ribose)polymerase inhibitor, on the blood–brain barrier after traumatic brain injury in mice
- (2015) X. Tao et al. NEUROSCIENCE
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Glutathione in multiple sclerosis: More than just an antioxidant?
- (2014) Andreia N Carvalho et al. Multiple Sclerosis Journal
- Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer
- (2014) Stephen P J Fancy et al. NATURE NEUROSCIENCE
- Neurobiology of premature brain injury
- (2014) Natalina Salmaso et al. NATURE NEUROSCIENCE
- Another “String to the Bow” of PJ34, a Potent Poly(ADP-Ribose)Polymerase Inhibitor: An Antiplatelet Effect through P2Y12 Antagonism?
- (2014) Marie Lechaftois et al. PLoS One
- Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis
- (2013) Amit Kamboj et al. Journal of Neuroinflammation
- Oligodendrocyte Lineage Cells Contribute Unique Features to Rett Syndrome Neuropathology
- (2013) M. V. C. Nguyen et al. JOURNAL OF NEUROSCIENCE
- Adenomatous Polyposis Coli Regulates Oligodendroglial Development
- (2013) J. Lang et al. JOURNAL OF NEUROSCIENCE
- PARP-1 Inhibition Attenuates Neuronal Loss, Microglia Activation and Neurological Deficits after Traumatic Brain Injury
- (2013) Bogdan A. Stoica et al. JOURNAL OF NEUROTRAUMA
- FMRP and myelin protein expression in oligodendrocytes
- (2013) Anthony Giampetruzzi et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Site-specific characterization of the Asp- and Glu-ADP-ribosylated proteome
- (2013) Yajie Zhang et al. NATURE METHODS
- A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
- (2013) L. Lande-Diner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species
- (2013) Bridgette D. Semple et al. PROGRESS IN NEUROBIOLOGY
- Identification of Pim Kinases as Novel Targets for PJ34 with Confounding Effects in PARP Biology
- (2012) Albert A. Antolín et al. ACS Chemical Biology
- Translational control by 3'-UTR-binding proteins
- (2012) E. Szostak et al. Briefings in Functional Genomics
- On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
- (2012) X. Luo et al. GENES & DEVELOPMENT
- PARP-1 deletion promotes subventricular zone neural stem cells toward a glial fate
- (2012) Jennifer M. Plane et al. JOURNAL OF NEUROSCIENCE RESEARCH
- The T3-induced gene KLF9 regulates oligodendrocyte differentiation and myelin regeneration
- (2012) Jason C. Dugas et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
- (2012) Elisabet Wahlberg et al. NATURE BIOTECHNOLOGY
- Global Profiling of Alternative Splicing Events and Gene Expression Regulated by hnRNPH/F
- (2012) Erming Wang et al. PLoS One
- Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases
- (2012) William M. Johnson et al. Nutrients
- Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β
- (2011) Tiina M Kauppinen et al. Journal of Neuroinflammation
- PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity
- (2011) Leonardo Cavone et al. Multiple Sclerosis Journal
- Targeting poly(ADP-ribose) polymerase-1 as a promising approach for immunomodulation in multiple sclerosis?
- (2011) Leonardo Cavone et al. TRENDS IN MOLECULAR MEDICINE
- Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death
- (2010) S. Veto et al. BRAIN
- NAD+ Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death
- (2010) C. C. Alano et al. JOURNAL OF NEUROSCIENCE
- Phosphorylation-Dependent Regulation of PSF by GSK3 Controls CD45 Alternative Splicing
- (2010) Florian Heyd et al. MOLECULAR CELL
- TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation
- (2010) Kuo-Ming Lee et al. NUCLEIC ACIDS RESEARCH
- Inhibition of matrix metalloproteinase-2 by PARP inhibitors
- (2009) Adrian C. Nicolescu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The molecular "Jekyll and Hyde" duality of PARP1 in cell death and cell survival
- (2009) Paul et al. Frontiers in Bioscience-Landmark
- Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
- (2009) S. P.J. Fancy et al. GENES & DEVELOPMENT
- PARP-1 Deficiency Increases the Severity of Disease in a Mouse Model of Multiple Sclerosis
- (2009) Vimal Selvaraj et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
- (2009) Mauricio F Farez et al. NATURE IMMUNOLOGY
- Acquisition of Granule Neuron Precursor Identity Is a Critical Determinant of Progenitor Cell Competence to Form Shh-Induced Medulloblastoma
- (2008) Ulrich Schüller et al. CANCER CELL
- Trading translation with RNA-binding proteins
- (2008) I. Abaza et al. RNA
- Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes
- (2008) R. Krishnakumar et al. SCIENCE
- Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage
- (2007) F MORONI CURRENT OPINION IN PHARMACOLOGY
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