Developing a far-red fluorogenic beta-galactosidase probe for senescent cell imaging and photoablation

Chromo-fluorogenic probes for β-galactosidase detection

(2021) Beatriz Lozano-Torres et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Biological functions of therapy-induced senescence in cancer

(2021) Eleni Fitsiou et al.   SEMINARS IN CANCER BIOLOGY

Real time in vivo detection of cellular senescence through the controlled release of the NIR fluorescent dye Nile Blue

(2020) Beatriz Lozano-Torres et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-throughput and label-free isolation of senescent murine mesenchymal stem cells

(2020) Zhengkun Chen et al.   Biomicrofluidics

Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice

(2020) Yusheng Cai et al.   CELL RESEARCH

A Senescence-Centric View of Aging: Implications for Longevity and Disease

(2020) M. Borghesan et al.   TRENDS IN CELL BIOLOGY

A guide to assessing cellular senescence in vitro and in vivo

(2020) Estela González‐Gualda et al.   FEBS Journal

Cellular senescence in ageing: from mechanisms to therapeutic opportunities

(2020) Raffaella Di Micco et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Senolytic therapies for healthy longevity

(2019) Jan M. van Deursen   SCIENCE

Activatable Photosensitizer for Targeted Ablation of lacZ-Positive Cells with Single-Cell Resolution

(2019) Mayumi Chiba et al.   ACS Central Science

Development of highly sensitive fluorescent probes for the detection of β-galactosidase activity – application to the real-time monitoring of senescence in live cells

(2018) Mauro Safir Filho et al.   ANALYST

Real-Time Visualization of Lysosome Destruction Using a Photosensitive Toluidine Blue Nanogel

(2018) Weiqi Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ionizing radiation-induced cellular senescence promotes tissue fibrosis after radiotherapy. A review

(2018) Hoang Quy Nguyen et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

A versatile drug delivery system targeting senescent cells

(2018) Daniel Muñoz‐Espín et al.   EMBO Molecular Medicine

Microfluidic label-free selection of mesenchymal stem cell subpopulation during culture expansion extends the chondrogenic potential in vitro

(2018) Lu Yin et al.   LAB ON A CHIP

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

Red-shifted fluorogenic substrate for detecting lacZ-positive cells in living tissue with single-cell resolution

(2018) Hiroki Ito et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cellular senescence: Molecular mechanisms and pathogenicity

(2018) Wenqiang Wei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers

(2017) Smruthi Vijayaraghavan et al.   Nature Communications

Selective Ablation of β-Galactosidase-Expressing Cells with a Rationally Designed Activatable Photosensitizer

(2014) Yuki Ichikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The art of reporter proteins in science: past, present and future applications

(2011) Cheol-Min Ghim et al.   BMB Reports

Design and Development of Enzymatically Activatable Photosensitizer Based on Unique Characteristics of Thiazole Orange

(2009) Yuichiro Koide et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the Utility of β-Galactosidase Complementation: Piece by Piece

(2009) Ann-Marie Broome et al.   MOLECULAR PHARMACEUTICS