Autonomic Nervous System Neuroanatomical Alterations Could Provoke and Maintain Gastrointestinal Dysbiosis in Autism Spectrum Disorder (ASD): A Novel Microbiome–Host Interaction Mechanistic Hypothesis

Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?

(2020) Nermin Eissa et al.   Frontiers in Pharmacology

Autism spectrum disorder and pupillometry: A systematic review and meta-analysis

(2020) Lyssa de Vries et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Distinct Fecal and Plasma Metabolites in Children with Autism Spectrum Disorders and Their Modulation after Microbiota Transfer Therapy

(2020) Dae-Wook Kang et al.   mSphere

Loss of intestinal sympathetic innervation elicits an innate immune driven colitis

(2019) Rose A. Willemze et al.   MOLECULAR MEDICINE

Autonomic nervous system and neuroimmune interactions

(2019) Eduardo E. Benarroch   NEUROLOGY

Characterizing the Interplay Between Autism Spectrum Disorder and Comorbid Medical Conditions: An Integrative Review

(2019) Charlotte Tye et al.   Frontiers in Psychiatry

Clostridium difficile Modulates the Gut Microbiota by Inducing the Production of Indole, an Interkingdom Signaling and Antimicrobial Molecule

(2019) Charles Darkoh et al.   mSystems

Current Understanding of Gut Microbiota in Mood Disorders: An Update of Human Studies

(2019) Ting-Ting Huang et al.   Frontiers in Genetics

Targeting the immune system in the treatment of bipolar disorder

(2019) Joshua D. Rosenblat   PSYCHOPHARMACOLOGY

Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota

(2019) Dae-Wook Kang et al.   Scientific Reports

Microbiota transplant therapy and autism: lessons for the clinic

(2019) James B. Adams et al.   Expert Review of Gastroenterology & Hepatology

Transient Osmotic Perturbation Causes Long-Term Alteration to the Gut Microbiota

(2018) Carolina Tropini et al.   CELL

The Hypothalamic-Pituitary-Adrenal Axis: A Brief History

(2018) Walter L. Miller   Hormone Research in Paediatrics

Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: a randomized clinical trial

(2018) Hidenori Yamasue et al.   MOLECULAR PSYCHIATRY

Impact of Intestinal Peptides on the Enteric Nervous System: Novel Approaches to Control Glucose Metabolism and Food Intake

(2018) Anne Abot et al.   Frontiers in Endocrinology

How scientific literature analysis yields innovative therapeutic hypothesis through integrative iterations

(2018) Francois Iris et al.   CURRENT OPINION IN PHARMACOLOGY

Neuro-immune regulation of mucosal physiology

(2018) Julie Chesné et al.   Mucosal Immunology

Colonic levels of vasoactive intestinal peptide decrease during infection and exogenous VIP protects epithelial mitochondria against the negative effects of IFNγ and TNFα induced during Citrobacter rodentium infection

(2018) Arpan K. Maiti et al.   PLoS One

Heart rate variability of typically developing and autistic children and adults before, during and after sleep

(2018) Marie-Pierre Tessier et al.   INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY

Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder

(2018) Martina Sgritta et al.   NEURON

Prosocial effects of an oxytocin metabolite, but not synthetic oxytocin receptor agonists, in a mouse model of autism

(2018) Sheryl S. Moy et al.   NEUROPHARMACOLOGY

Neural modulation of social reinforcement learning by intranasal oxytocin in male adults with high-functioning autism spectrum disorder: a randomized trial

(2018) Jana A. Kruppa et al.   NEUROPSYCHOPHARMACOLOGY

Supplement intervention associated with nutritional deficiencies in autism spectrum disorders: a systematic review

(2017) Yong-Jiang Li et al.   EUROPEAN JOURNAL OF NUTRITION

Variations in gut microbiota and fecal metabolic phenotype associated with depression by 16S rRNA gene sequencing and LC/MS-based metabolomics

(2017) Meng Yu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides

(2017) Gilliard Lach et al.   Neurotherapeutics

Nutritional and Dietary Interventions for Autism Spectrum Disorder: A Systematic Review

(2017) Nila Sathe et al.   PEDIATRICS

Intranasal oxytocin treatment for social deficits and biomarkers of response in children with autism

(2017) Karen J. Parker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes, DAMPs and miRNA: Features of Stress Physiology and Immune Homeostasis

(2017) Monika Fleshner et al.   TRENDS IN IMMUNOLOGY

Gut Microbial Influences on the Mammalian Intestinal Stem Cell Niche

(2017) Bailey C. E. Peck et al.   Stem Cells International

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

(2017) Dae-Wook Kang et al.   Microbiome

Respiratory and autonomic dysfunction in children with autism spectrum disorders

(2016) Xue Ming et al.   BRAIN & DEVELOPMENT

Exosome in intestinal mucosal immunity

(2016) An Tao Xu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Anti-inflammatory properties of the vagus nerve: potential therapeutic implications of vagus nerve stimulation

(2016) Bruno Bonaz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

(2016) John R. Kelly et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Gut microbiota in autism and mood disorders

(2016) Francesca Mangiola   WORLD JOURNAL OF GASTROENTEROLOGY

Mosquito C-type lectins maintain gut microbiome homeostasis

(2016) Xiaojing Pang et al.   Nature Microbiology

Vagal nerve stimulation activates vagal afferent fibers that reduce cardiac efferent parasympathetic effects

(2015) Kentaro Yamakawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

(2015) Lieve Desbonnet et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered fecal microbiota composition in patients with major depressive disorder

(2015) Haiyin Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: Evidence, pathophysiology and treatment implications

(2015) Joshua D. Rosenblat et al.   JOURNAL OF AFFECTIVE DISORDERS

Recognition of Bacterial Signal Peptides by Mammalian Formyl Peptide Receptors

(2015) Bernd Bufe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gut/brain axis and the microbiota

(2015) Emeran A. Mayer et al.   JOURNAL OF CLINICAL INVESTIGATION

The gut microbiome restores intrinsic and extrinsic nerve function in germ-free mice accompanied by changes in calbindin

(2015) K. A. McVey Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo

(2015) Markus Nussbaumer et al.   NEUROPSYCHOPHARMACOLOGY

Fate, activity, and impact of ingested bacteria within the human gut microbiota

(2015) Muriel Derrien et al.   TRENDS IN MICROBIOLOGY

Microbiota and host determinants of behavioural phenotype in maternally separated mice

(2015) G. De Palma et al.   Nature Communications

The Enteric Nervous System Neuropeptide, Bombesin, Reverses Innate Immune Impairments During Parenteral Nutrition

(2014) Rebecca A. Busch et al.   ANNALS OF SURGERY

Glucagon-like peptide 1 and peptide YY are in separate storage organelles in enteroendocrine cells

(2014) Hyun-Jung Cho et al.   CELL AND TISSUE RESEARCH

Cooperativity among secretory IgA, the polymeric immunoglobulin receptor, and the gut microbiota promotes host–microbial mutualism

(2014) Charlotte S. Kaetzel   IMMUNOLOGY LETTERS

Nucleotide-Binding Oligomerization Domain–Containing Protein 2 Controls Host Response to Campylobacter jejuni in Il10−/− Mice

(2014) Xiaolun Sun et al.   JOURNAL OF INFECTIOUS DISEASES

Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system

(2014) Sabrina Coquenlorge et al.   Journal of Neuroinflammation

Correlation between the human fecal microbiota and depression

(2014) A. Naseribafrouei et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Neuro-Anatomical Evidence Indicating Indirect Modulation of Macrophages by Vagal Efferents in the Intestine but Not in the Spleen

(2014) Cathy Cailotto et al.   PLoS One

Long-Term Administration of Intranasal Oxytocin Is a Safe and Promising Therapy for Early Adolescent Boys with Autism Spectrum Disorders

(2013) Masaya Tachibana et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Parenteral Nutrition Decreases Paneth Cell Function and Intestinal Bactericidal Activity While Increasing Susceptibility to Bacterial Enteroinvasion

(2013) Aaron F. Heneghan et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Microbiota is essential for social development in the mouse

(2013) L Desbonnet et al.   MOLECULAR PSYCHIATRY

Impact of intestinal electrical stimulation on nutrient-induced GLP-1 secretionin vivo

(2013) D. Sandoval et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Intestinal microbiota influence the early postnatal development of the enteric nervous system

(2013) J. Collins et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

(2013) Dae-Wook Kang et al.   PLoS One

Lymphocyte-derived ACh regulates local innate but not adaptive immunity

(2013) Colin Reardon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteroides fragilis polysaccharide A is necessary and sufficient for acute activation of intestinal sensory neurons

(2013) Yu-Kang Mao et al.   Nature Communications

Increased abundance of Sutterella spp. and Ruminococcus torques in feces of children with autism spectrum disorder

(2013) Lv Wang et al.   Molecular Autism

Does the Human Gut Microbiota Contribute to the Etiology of Autism Spectrum Disorders?

(2012) Petra Louis   DIGESTIVE DISEASES AND SCIENCES

Gut microbiota disturbance during antibiotic therapy: a multi-omic approach

(2012) Ana Elena Pérez-Cobas et al.   GUT

The enteric nervous system and neurogastroenterology

(2012) John B. Furness   Nature Reviews Gastroenterology & Hepatology

The microbiome is essential for normal gut intrinsic primary afferent neuron excitability in the mouse

(2012) K. A. McVey Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Gastrointestinal Conditions in Children With Autism Spectrum Disorder: Developing a Research Agenda

(2012) Daniel L. Coury et al.   PEDIATRICS

Psychiatric Systems Medicine: Closer at Hand than Anticipated but not with the Expected Portrait

(2012) F. Iris   PHARMACOPSYCHIATRY

Application of Novel PCR-Based Methods for Detection, Quantitation, and Phylogenetic Characterization of Sutterella Species in Intestinal Biopsy Samples from Children with Autism and Gastrointestinal Disturbances

(2012) B. L. Williams et al.   mBio

The “cryptic” mechanism of action of glucagon-like peptide-2

(2011) Katherine J. Rowland et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

(2011) James B Adams et al.   BMC GASTROENTEROLOGY

Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome

(2011) P. B. Jeppesen et al.   GUT

Modélisation intégrative prédictive et biologie expérimentale

(2011) François Iris et al.   M S-MEDECINE SCIENCES

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut

(2011) N J Mantis et al.   Mucosal Immunology

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

(2011) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Repeated Restraint Stress Reduces the Number of IgA-Producing Cells in Peyer’s Patches

(2011) Beatriz Elina Martínez-Carrillo et al.   NEUROIMMUNOMODULATION

Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity

(2011) James B Adams et al.   Nutrition & Metabolism

Proteome-Based Pathway Modelling of Psychiatric Disorders

(2011) C. W. Turck et al.   PHARMACOPSYCHIATRY

Glucose sensing and signalling; regulation of intestinal glucose transport

(2011) S. P. Shirazi-Beechey et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

(2011) M. Rosas-Ballina et al.   SCIENCE

Pyrosequencing study of fecal microflora of autistic and control children

(2010) Sydney M. Finegold et al.   ANAEROBE

Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyntic mucosa

(2010) Andreas Stengel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation

(2010) Michael T. Bailey et al.   BRAIN BEHAVIOR AND IMMUNITY

Repeated restraint stress increases IgA concentration in rat small intestine

(2009) Humberto Reyna-Garfias et al.   BRAIN BEHAVIOR AND IMMUNITY

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Glucagon-Like Peptide-2 Increases Intestinal Lipid Absorption and Chylomicron Production via CD36

(2009) Joanne Hsieh et al.   GASTROENTEROLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohnʼs disease

(2009) Alan L. Buchman et al.   INFLAMMATORY BOWEL DISEASES

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

Nod2 is required for the regulation of commensal microbiota in the intestine

(2009) T. Petnicki-Ocwieja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Gut Feeling for Obesity: 7TM Sensors on Enteroendocrine Cells

(2008) Maja S. Engelstoft et al.   Cell Metabolism

Multi-layered regulation of intestinal antimicrobial defense

(2008) S. Mukherjee et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cholera Toxin Induces Sustained Hyperexcitability in Submucosal Secretomotor Neurons in Guinea Pig Jejunum

(2008) Rachel M. Gwynne et al.   GASTROENTEROLOGY

Secreted enteric antimicrobial activity localises to the mucus surface layer

(2008) U Meyer-Hoffert et al.   GUT

f-Met-Leu-Phe stimulates nitric oxide production in chick embryo neurons: the role of NF-kB

(2008) Antonia Cianciulli et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Expression and developmental regulation of oxytocin (OT) and oxytocin receptors (OTR) in the enteric nervous system (ENS) and intestinal epithelium

(2008) Martha G. Welch et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia

(2008) M. Rosas-Ballina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing

(2008) Les Dethlefsen et al.   PLOS BIOLOGY

Effect of restraint stress on the population of intestinal intraepithelial lymphocytes in mice

(2007) Adriana Jarillo-Luna et al.   BRAIN BEHAVIOR AND IMMUNITY