Targeting GATA1 and p2x7r Locus Binding in Spinal Astrocytes Suppresses Chronic Visceral Pain by Promoting DNA Demethylation

Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase

(2020) Sandra Catania et al.   CELL

MAFG-driven astrocytes promote CNS inflammation

(2020) Michael A. Wheeler et al.   NATURE

Estrogen modulation of pain perception with a novel 17β-estradiol pretreatment regime in ovariectomized rats

(2020) Wenxin Zhang et al.   Biology of Sex Differences

Approaches for designing and discovering purinergic drugs for gastrointestinal diseases

(2020) Diego Dal Ben et al.   Expert Opinion on Drug Discovery

SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury

(2020) Andrew D. Sauerbeck et al.   NEURON

Whole-genome sequencing of patients with rare diseases in a national health system

(2020) Ernest Turro et al.   NATURE

TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers

(2020) Jocelyn Charlton et al.   NATURE GENETICS

Sleep Deprivation Selectively Down-Regulates Astrocytic 5-HT2B Receptors and Triggers Depressive-Like Behaviors via Stimulating P2X7 Receptors in Mice

(2020) Maosheng Xia et al.   Neuroscience Bulletin

Purinergic Receptors in Basal Ganglia Diseases: Shared Molecular Mechanisms between Huntington’s and Parkinson’s Disease

(2020) Talita Glaser et al.   Neuroscience Bulletin

Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue

(2019) Jun Nagai et al.   CELL

A vitamin-C-derived DNA modification catalysed by an algal TET homologue

(2019) Jian-Huang Xue et al.   NATURE

Chromatin occupancy and epigenetic analysis reveal new insights into the function of GATA1 N-terminus in erythropoiesis

(2019) Te Ling et al.   BLOOD

Astrocytes in chronic pain and itch

(2019) Ru-Rong Ji et al.   NATURE REVIEWS NEUROSCIENCE

Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization

(2019) Alanna E. McCarthy et al.   CELL

Multi-omics profiling of mouse gastrulation at single-cell resolution

(2019) Ricard Argelaguet et al.   NATURE

Epigenetic upregulation of acid-sensing ion channel 1 contributes to gastric hypersensitivity in adult offspring rats with prenatal maternal stress

(2019) Hong-Jun Wang et al.   PAIN

Absence of Wdr13 Gene Predisposes Mice to Mild Social Isolation – Chronic Stress, Leading to Depression-Like Phenotype Associated With Differential Expression of Synaptic Proteins

(2018) Shiladitya Mitra et al.   Frontiers in Molecular Neuroscience

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells

(2018) Henrique Borges da Silva et al.   NATURE

A changing paradigm of transcriptional memory propagation through mitosis

(2018) Katherine C. Palozola et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Author Correction: Epigenetic regulation in psychiatric disorders

(2018) Nadia Tsankova et al.   NATURE REVIEWS NEUROSCIENCE

Neuronal P2X7 Receptors Revisited: Do They Really Exist?

(2017) Peter Illes et al.   JOURNAL OF NEUROSCIENCE

P2X7 receptor-sensitivity of astrocytes and neurons in the substantia gelatinosa of organotypic spinal cord slices of the mouse depends on the length of the culture period

(2017) Po Gao et al.   NEUROSCIENCE

The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain

(2017) Farraj Albalawi et al.   Frontiers in Cellular Neuroscience

Neonatal Colonic Inflammation Increases Spinal Transmission and Cystathionine β-Synthetase Expression in Spinal Dorsal Horn of Rats with Visceral Hypersensitivity

(2017) Liting Zhao et al.   Frontiers in Pharmacology

Purinergic Signalling: Therapeutic Developments

(2017) Geoffrey Burnstock   Frontiers in Pharmacology

Neonatal Maternal Deprivation Enhances Presynaptic P2X7 Receptor Transmission in Insular Cortex in an Adult Rat Model of Visceral Hypersensitivity

(2016) Ping-An Zhang et al.   CNS Neuroscience & Therapeutics

An introduction to the roles of purinergic signalling in neurodegeneration, neuroprotection and neuroregeneration

(2016) Geoffrey Burnstock   NEUROPHARMACOLOGY

Reversible Induction of Pain Hypersensitivity following Optogenetic Stimulation of Spinal Astrocytes

(2016) Youngpyo Nam et al.   Cell Reports

Glial contributions to visceral pain: implications for disease etiology and the female predominance of persistent pain

(2016) K N Dodds et al.   Translational Psychiatry

Promoted Interaction of Nuclear Factor-κB With Demethylated Purinergic P2X3 Receptor Gene Contributes to Neuropathic Pain in Rats With Diabetes

(2015) Hong-Hong Zhang et al.   DIABETES

Delayed Activation of Spinal Microglia Contributes to the Maintenance of Bone Cancer Pain in Female Wistar Rats via P2X7 Receptor and IL-18

(2015) Y. Yang et al.   JOURNAL OF NEUROSCIENCE

Enhanced binding capability of nuclear factor-κB with demethylated P2X3 receptor gene contributes to cancer pain in rats

(2015) You-Lang Zhou et al.   PAIN

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

(2012) Hyo Jung Kang et al.   NATURE MEDICINE

Primary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1

(2009) Ying Zhang et al.   NUCLEIC ACIDS RESEARCH

P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity

(2008) G-Y Xu et al.   GUT

Inside Information: The Unique Features of Visceral Sensation

(2008) D. R. Robinson et al.   MOLECULAR INTERVENTIONS